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Xenobiotica
the fate of foreign compounds in biological systems
Volume 46, 2016 - Issue 10
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Animal Pharmacokinetics and Metabolism

In vivo drug metabolite identification in preclinical ADME studies by means of UPLC/TWIMS/high resolution-QTOF MSE and control comparison: cost and benefit of vehicle-dosed control samples

Lukas FiebigDepartment of Drug Metabolism & Pharmacokinetics, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach (Riß), GermanyCorrespondence[email protected]
,
Ralf LauxDepartment of Drug Metabolism & Pharmacokinetics, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach (Riß), Germany
,
Rudolf BinderDepartment of Drug Metabolism & Pharmacokinetics, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach (Riß), Germany
&
Thomas EbnerDepartment of Drug Metabolism & Pharmacokinetics, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach (Riß), Germany
Pages 922-930 | Received 28 Oct 2015, Accepted 13 Jan 2016, Published online: 19 Feb 2016

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