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Bioanalysis Volume 9, 2017 - Issue 5
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Methodology

LC–MS/MS Determination of Alectinib and its Major Human Metabolite M4 in Human Urine: Prevention of Nonspecific Binding

Katja Heinig1 Roche Pharmaceutical Research & Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Grenzacherstrasse 124, 4070Basel, SwitzerlandCorrespondence[email protected]
,
Denis Herzog1 Roche Pharmaceutical Research & Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Grenzacherstrasse 124, 4070Basel, Switzerland
,
Luca Ferrari1 Roche Pharmaceutical Research & Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Grenzacherstrasse 124, 4070Basel, Switzerland
,
Daniela Fraier1 Roche Pharmaceutical Research & Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Grenzacherstrasse 124, 4070Basel, Switzerland
,
Kazuhiro Miya2 Kamakura Research Laboratories, Chugai Pharmaceutical Co., Ltd., 200 Kajiwara, Kamakura, Kanagawa, 247-8530, Japan
&
Peter N Morcos3 Roche Pharmaceutical Research & Early Development, Clinical Pharmacology, Roche Innovation Center, New York, NY, USA
Pages 459-468 | Received 09 Nov 2016, Accepted 05 Jan 2017, Published online: 08 Feb 2017

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