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Bioanalysis Volume 9, 2017 - Issue 19

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Research Article

2D-LC–MS/MS to Measure Cleaved High-Molecular-Weight Kininogen in Human Plasma as A Biomarker for C1-Inh-Hae

Guodong Zhang1 Bioanalytical & Biomarker Development, Research & Nonclinical Development, Shire, Lexington, MA02421, USACorrespondence[email protected]

Daniel J Sexton2 Pharmacology, Research & Nonclinical Development, Shire, Lexington, MA02421, USA

Ryan R Faucette1 Bioanalytical & Biomarker Development, Research & Nonclinical Development, Shire, Lexington, MA02421, USA;3 Scholar Rock, Cambridge, MA02139, USA

Yongchang Qiu1 Bioanalytical & Biomarker Development, Research & Nonclinical Development, Shire, Lexington, MA02421, USA

Jiang Wu1 Bioanalytical & Biomarker Development, Research & Nonclinical Development, Shire, Lexington, MA02421, USACorrespondence[email protected]

Pages 1477-1491 | Received 10 May 2017, Accepted 03 Aug 2017, Published online: 21 Oct 2017

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https://doi.org/10.4155/bio-2017-0105
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