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International Journal of Pharmacokinetics Volume 2, 2017 - Issue 4
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Research Article

Population Pharmacokinetics of Exogenous Biotin and the Relationship Between Biotin Serum Levels and In Vitro Immunoassay Interference

Paul Grimsey1 Roche Pharmaceuticals, Roche Innovation Center Welwyn, Welywn Garden City, UKView further author information
,
Nicolas Frey2 Roche Pharmaceuticals, Basel, SwitzerlandView further author information
,
Garnet Bendig3 Roche Diagnostics GmbH, Penzberg, GermanyView further author information
,
Juergen Zitzler3 Roche Diagnostics GmbH, Penzberg, GermanyView further author information
,
Oliver Lorenz3 Roche Diagnostics GmbH, Penzberg, GermanyView further author information
,
Dusanka Kasapic4 Roche Diagnostics International Ltd, Forrenstrasse 2, CH-6343Rotkreuz, SwitzerlandView further author information
&
Christian E Zaugg4 Roche Diagnostics International Ltd, Forrenstrasse 2, CH-6343Rotkreuz, SwitzerlandCorrespondence[email protected]
View further author information
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Pages 247-256 | Received 11 Jul 2017, Accepted 31 Aug 2017, Published online: 14 Sep 2017
Supplemental material

Supplementary Table 1. Time taken for biotin concentrations to reach of thresholds of 10-100 ng/ml*.

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