Key tumor suppressor genes inactivated by “greater promoter” methylation and somatic mutations in head and neck cancer

Rafael Guerrero-Preston Department of Otolaryngology and Head and Neck Surgery; Johns Hopkins University; School of Medicine; Baltimore, MD USA; Department of Obstetrics and Gynecology; University of Puerto Rico School of Medicine; Río Piedras, Puerto RicoCorrespondence[email protected] [email protected]

Christina Michailidi Department of Otolaryngology and Head and Neck Surgery; Johns Hopkins University; School of Medicine; Baltimore, MD USA

Luigi Marchionni Department of Oncology Biostatistics; Johns Hopkins University; School of Medicine; Baltimore, MD USA

Curtis R Pickering Department of Head and Neck Surgery; University of Texas M.D. Anderson Cancer Center; Houston, TX USA

Mitchell J Frederick Department of Head and Neck Surgery; University of Texas M.D. Anderson Cancer Center; Houston, TX USA

Jeffrey N Myers Department of Head and Neck Surgery; University of Texas M.D. Anderson Cancer Center; Houston, TX USA

Srinivasan Yegnasubramanian Sidney Kimmel Comprehensive Cancer Center; Johns Hopkins University; Baltimore, MD USA

Tal Hadar Department of Otolaryngology and Head and Neck Surgery; Johns Hopkins University; School of Medicine; Baltimore, MD USA

Maartje G Noordhuis Department of Otolaryngology and Head and Neck Surgery; Johns Hopkins University; School of Medicine; Baltimore, MD USA; Department of Otorhinolaryngology-Head and Neck Surgery; University of Groningen; University Medical Center; Groningen, The Netherlands

Veronika Zizkova Department of Otolaryngology and Head and Neck Surgery; Johns Hopkins University; School of Medicine; Baltimore, MD USA; Laboratory of Molecular Pathology and Institute of Molecular and Translational Medicine; Faculty of Medicine and Dentistry; Palacky University; Olomouc, Czech Republic

Elana Fertig Division of Biostatistics and Bioinformatics; Department of Oncology; Sidney Kimmel Comprehensive Cancer Center; Baltimore, MD USA

Nishant Agrawal Department of Otolaryngology and Head and Neck Surgery; Johns Hopkins University; School of Medicine; Baltimore, MD USA; Sidney Kimmel Comprehensive Cancer Center; Johns Hopkins University; Baltimore, MD USA

William Westra Department of Otolaryngology and Head and Neck Surgery; Johns Hopkins University; School of Medicine; Baltimore, MD USA

Wayne Koch Department of Otolaryngology and Head and Neck Surgery; Johns Hopkins University; School of Medicine; Baltimore, MD USA

Joseph Califano Department of Otolaryngology and Head and Neck Surgery; Johns Hopkins University; School of Medicine; Baltimore, MD USA; Milton J. Dance Head and Neck Center; Greater Baltimore Medical Center; Baltimore, MD USA

Victor E Velculescu Sidney Kimmel Comprehensive Cancer Center; Johns Hopkins University; Baltimore, MD USA

David Sidransky Department of Otolaryngology and Head and Neck Surgery; Johns Hopkins University; School of Medicine; Baltimore, MD USACorrespondence[email protected] [email protected]

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Key tumor suppressor genes inactivated by “greater promoter” methylation and somatic mutations in head and neck cancer

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Key tumor suppressor genes inactivated by “greater promoter” methylation and somatic mutations in head and neck cancer

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