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Recombinant approaches to IgG-like bispecific antibodies
Source:
Springer Science and Business Media LLC
Altered expression of angiopoietins and Tie2 endothelium receptor in psoriasis.
Source:
The Society for Investigative Dermatology, Inc.
Chemical generation of bispecific antibodies
Source:
Proceedings of the National Academy of Sciences
Angiopoietins have distinct modular domains essential for receptor binding, dimerization and superclustering
Source:
Springer Science and Business Media LLC
Transmembrane TNF-α: structure, function and interaction with anti-TNF agents
Source:
Oxford University Press (OUP)
TNF-α antagonists beyond approved indications: stories of success and prospects for the future.
Source:
Oxford University Press (OUP)
Excess circulating angiopoietin-2 levels in sepsis: harbinger of death in the intensive care unit?
Source:
Springer Science and Business Media LLC
Comparisons of affinities, avidities, and complement activation of adalimumab, infliximab, and etanercept in binding to soluble and membrane tumor necrosis factor.
Source:
Elsevier BV
Complementary Actions of Inhibitors of Angiopoietin-2 and VEGF on Tumor Angiogenesis and Growth
Source:
American Association for Cancer Research (AACR)
Stability engineering of scFvs for the development of bispecific and multivalent antibodies
Source:
Oxford University Press (OUP)
Tie2 Receptor Ligands, Angiopoietin-1 and Angiopoietin-2, Modulate VEGF-Induced Postnatal Neovascularization
Source:
Ovid Technologies (Wolters Kluwer Health)
Angiopoietin-2 at high concentration can enhance endothelial cell survival through the phosphatidylinositol 3-kinase/Akt signal transduction pathway.
Source:
Springer Science and Business Media LLC
Isolation of Angiopoietin-1, a Ligand for the TIE2 Receptor, by Secretion-Trap Expression Cloning
Source:
Elsevier BV
Role of angiogenesis in inflammatory bowel disease.
Source:
Oxford University Press (OUP)
Angiopoietin-2 sensitizes endothelial cells to TNF-alpha and has a crucial role in the induction of inflammation.
Source:
Springer Science and Business Media LLC
The making of bispecific antibodies
Source:
Taylor & Francis
Suppression of angiogenesis and tumor growth by selective inhibition of angiopoietin-2.
Source:
Cell Press.
The Tie-2 ligand angiopoietin-2 is stored in and rapidly released upon stimulation from endothelial cell Weibel-Palade bodies.
Source:
American Society of Hematology
Affibody molecules as engineered protein drugs
Source:
Uppsala universitet, Medicinsk strålningsvetenskap
Attenuation of inflammatory polyarthritis in TNF transgenic mice by diacerein: comparative analysis with dexamethasone, methotrexate and anti-TNF protocols
Source:
Springer Science and Business Media LLC
Prevention of LPS-induced acute lung injury in mice by mesenchymal stem cells overexpressing angiopoietin 1.
Source:
Public Library of Science (PLoS)
Engineering of a GLP-1 analogue peptide/anti-PCSK9 antibody fusion for type 2 diabetes treatment
Source:
Nature Publishing Group
Angiopoietin-2 and inflammation
Source:
Wiley
A stable IgG-like bispecific antibody targeting the epidermal growth factor receptor and the type I insulin-like growth factor receptor demonstrates superior anti-tumor activity
Source:
Informa UK Limited
Anti-inflammatory effects of Angiopoietin-1
Source:
Wiley
Mechanism of action of certolizumab pegol (CDP870): In vitro comparison with other anti-tumor necrosis factor α agents
Source:
Oxford University Press (OUP)
Angiopoietins: a link between angiogenesis and inflammation.
Source:
Elsevier BV
Anti-TNF-α antibody allows healing of joint damage in polyarthritic transgenic mice
Source:
Springer Science and Business Media LLC
Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritis.
Source:
Wiley
Single-chain antibodies as diagnostic tools and therapeutic agents
Source:
Georg Thieme Verlag KG
Double Anti-angiogenic and Anti-inflammatory Protein Valpha Targeting VEGF-A and TNF-α in Retinopathy and Psoriasis *
Source:
Elsevier BV
AMG 386: profile of a novel angiopoietin antagonist in patients with ovarian cancer.
Source:
Informa Healthcare
Proinflammatory activation pattern of human umbilical vein endothelial cells induced by IL-1β, TNF-α, and LPS.
Source:
Wiley
Angiopoietin-1 Is an Antipermeability and Anti-Inflammatory Agent In Vitro and Targets Cell Junctions
Source:
Ovid Technologies (Wolters Kluwer Health)
Bispecific Antibodies for Autoimmune and Inflammatory Diseases: Clinical Progress to Date.
Source:
Springer Science and Business Media LLC
Neutralization of Vascular Endothelial Growth Factor Prevents Collagen-Induced Arthritis and Ameliorates Established Disease in Mice☆
Source:
Elsevier BV
Treatment of rheumatoid arthritis: state of the art 2009.
Source:
Springer Science and Business Media LLC
Adalimumab Modulates Angiogenesis in Psoriatic Skin
Source:
SAGE Publishing
Requisite Role of Angiopoietin-1, a Ligand for the TIE2 Receptor, during Embryonic Angiogenesis
Source:
Elsevier BV
Angiopoietin-2 promotes myeloid cell infiltration in a β2-integrin–dependent manner
Source:
American Society of Hematology
Angiopoietin-2, a Natural Antagonist for Tie2 That Disrupts in vivo Angiogenesis
Source:
American Association for the Advancement of Science (AAAS)
Serum angiopoietin-2 in COPD
Source:
Wiley
Therapeutic targeting of the angiopoietin–TIE pathway
Source:
Springer Science and Business Media LLC
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