Itch as a New Therapeutic Frontier

Created 14 Jun 2024 | 2 articles
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The field of itch biology is currently undergoing a transformative translational revolution, where fundamental discoveries at the molecular and neuronal levels are rapidly translating into innovative clinical applications. Previously relegated to the side-lines of sensory research, itch has gained significant recognition as a distinct sensory modality with its own intricate pathways and mechanisms. The elucidation of pruritus-associated receptors, neural circuits, and immune interactions has paved the way for targeted therapeutic interventions, offering relief to individuals burdened by chronic itch conditions. This translational momentum holds the promise of not only alleviating disease burden with novel therapeutics, but also deepening our comprehension of broader neurobiological processes. As itch biology enters this exciting phase, collaborations between basic scientists, clinicians, and industry partners are fostering a dynamic landscape where bench-to-bedside advancements are poised to revolutionize how we understand and manage itch.

This Collection aims to shine a spotlight on itch, highlighting emerging mechanisms underlying itch pathologies, clinical management of pruritic conditions, and the novel therapeutics in development. This collection welcomes original research articles, reviews, and clinical studies that contribute to the growing body of knowledge surrounding itch.

Potential topics for submission include, but are not limited to: Neurobiological basis of itch; sensation; Neuroimmune interactions contributing to itch; Itch in diseases such as urticaria, atopic dermatitis, prurigo nodularis, notalgia paresthetica, and chronic pruritus of unknown origin; Management of itch in dermatological and non-dermatological disorders; Novel therapeutic strategies for chronic itch

This Collection is currently open for submissions until 31st December 2024. Upon submission, please use the promo code IJDT-2024-C22630 for 10% off the advertised article processing charge and indicate that your manuscript will be considered for the “Itch as a New Therapeutic Frontier” Collection.