Hypoxia, Volume 5, Issue (2017)

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Hypoxia, Volume 5, Issue (2017)

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Original Research

Article
Induction of erythropoiesis by hypoxia-inducible factor prolyl hydroxylase inhibitors without promotion of tumor initiation, progression, or metastasis in a VEGF-sensitive model of spontaneous breast cancer
Todd W Seeley, Mark D Sternlicht, Stephen J Klaus, Thomas B Neff & David Y Liu
Pages: 1-9
Published online: 10 Mar 2017
AbstractforInduction of erythropoiesis by hypoxia-inducible factor prolyl hydroxylase inhibitors without promotion of tumor initiation, progression, or metastasis in a VEGF-sensitive model of spontaneous breast cancer | Full Text | References | PDF (595.8 KB)
  • 91 Views
  • 3 CrossRef citations
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Open Access

Review

Review Article
Update on hypoxia-inducible factors and hydroxylases in oxygen regulatory pathways: from physiology to therapeutics
Peter Ratcliffe, Peppi Koivunen, Johanna Myllyharju, Jiannis Ragoussis, Judith VMG Bovée, Ines Batinic-Haberle, Claire Vinatier, Valérie Trichet, Florence Robriquet, Lisa Oliver & Betty Gardie
Pages: 11-20
Published online: 15 Mar 2017
AbstractforUpdate on hypoxia-inducible factors and hydroxylases in oxygen regulatory pathways: from physiology to therapeutics | Full Text | References | PDF (935.8 KB)
  • 79 Views
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Open Access
Review Article
A review of the development of tumor vasculature and its effects on the tumor microenvironment
Jake C Forster, Wendy M Harriss-Phillips, Michael JJ Douglass & Eva Bezak
Pages: 21-32
Published online: 11 Apr 2017
AbstractforA review of the development of tumor vasculature and its effects on the tumor microenvironment | Full Text | References | PDF (1.3 MB)
  • 510 Views
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Open Access

Original Research

Article
Neuroprotection via RNA-binding protein RBM3 expression is regulated by hypothermia but not by hypoxia in human SK-N-SH neurons
Lisa-Maria Rosenthal, Giang Tong, Christoph Walker, Sylvia J Wowro, Jana Krech, Constanze Pfitzer, Georgia Justus, Felix Berger & Katharina Rose Luise Schmitt
Pages: 33-43
Published online: 23 May 2017
AbstractforNeuroprotection via RNA-binding protein RBM3 expression is regulated by hypothermia but not by hypoxia in human SK-N-SH neurons | Full Text | References | PDF (869.4 KB)
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Open Access
Article
KEMTUB012-NI2, a novel potent tubulysin analog that selectively targets hypoxic cancer cells and is potentiated by cytochrome p450 reductase downregulation
Paolo Lazzari, Marco Spiga, Monica Sani, Matteo Zanda & Ian N Fleming
Pages: 45-59
Published online: 23 May 2017
AbstractforKEMTUB012-NI2, a novel potent tubulysin analog that selectively targets hypoxic cancer cells and is potentiated by cytochrome p450 reductase downregulation | Full Text | References | PDF (1.5 MB)
  • 65 Views
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Open Access
Article
Targeted metabolomics in colorectal cancer: a strategic approach using standardized laboratory tests of the blood and urine
Katarzyna J Jerzak, Marissa Laureano, Radwa Elsharawi, Peter Kavsak, Kelvin KW Chan, Sukhbinder K Dhesy-Thind & Kevin Zbuk
Pages: 61-66
Published online: 24 May 2017
AbstractforTargeted metabolomics in colorectal cancer: a strategic approach using standardized laboratory tests of the blood and urine | Full Text | References | PDF (222.7 KB)
  • 66 Views
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Open Access
Article
SNPs, linkage disequilibrium, and chronic mountain sickness in Tibetan Chinese
Norman E Buroker, Xue-Han Ning, Zhao-Nian Zhou, Kui Li, Wei-Jun Cen, Xiu-Feng Wu, Wei-Zhong Zhu, C Ronald Scott & Shi-Han Chen
Pages: 67-74
Published online: 14 Jul 2017
AbstractforSNPs, linkage disequilibrium, and chronic mountain sickness in Tibetan Chinese | Full Text | References | PDF (697.3 KB)
  • 75 Views
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Review

Review Article
Respiratory muscle dysfunction in animal models of hypoxic disease: antioxidant therapy goes from strength to strength
Ken D O’Halloran & Philip Lewis
Pages: 75-84
Published online: 14 Jul 2017
AbstractforRespiratory muscle dysfunction in animal models of hypoxic disease: antioxidant therapy goes from strength to strength | Full Text | References | PDF (326.7 KB)
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Open Access

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Markers of Hypoxia Correlate with Histologic and Endoscopic Severity of Colitis in Inflammatory Bowel Disease
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Article | Published online: 10 Feb 2020
Open Access
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Open Access
Hypoxia Induces Pro-Fibrotic and Fibrosis Marker Genes in Hepatocellular Carcinoma Cells Independently of Inflammatory Stimulation and the NF-κΒ Pathway
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Open Access
Hypoxia Suppresses High Fat Diet-Induced Steatosis And Development Of Hepatic Adenomas
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Article | Published online: 21 Oct 2019
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