International Journal of High Throughput Screening, Volume 1, Issue (2010)

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International Journal of High Throughput Screening, Volume 1, Issue (2010)

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Original Research

Article
Open access liquid chromatography/tandem mass spectrometry: implementation of a fully quantitative system in a drug discovery laboratory
John G Swales, Gary Wilkinson, Richard Gallagher, Clare Hammond, Charles O’Donnell & Raimund Peter
Pages: 1-14
Published online: 23 Feb 2010
AbstractforOpen access liquid chromatography/tandem mass spectrometry: implementation of a fully quantitative system in a drug discovery laboratory | References | PDF (7.2 MB)
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Open Access

Methodology

Computational characterization of SAR microenvironments in high-throughput screening data
Mathias Wawer, Su Sun & Jürgen Bajorath
Pages: 15-27
Published online: 01 Apr 2010
AbstractforComputational characterization of SAR microenvironments in high-throughput screening data | References | PDF (1.5 MB)
  • 14 Views
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Open Access

Review

Review Article
High-throughput approaches to investigate neutral lipid biosynthesis
Rodrigo MP Siloto & Randall J Weselake
Pages: 29-38
Published online: 01 Apr 2010
AbstractforHigh-throughput approaches to investigate neutral lipid biosynthesis | References | PDF (350.7 KB)
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Open Access

Original Research

Article
Development of a functional HTS assay for the APJ receptor
Angela Giddings, Scott Runyon, James Thomas, Julianne Tajuba, Katherine Bortoff & Rangan Maitra
Pages: 39-47
Published online: 19 Apr 2010
AbstractforDevelopment of a functional HTS assay for the APJ receptor | References | PDF (292.8 KB)
  • 24 Views
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Open Access
Article
Cell line and drug-dependent effect of ERBB3 on cancer cell proliferation, chemosensitivity, and multidrug actions
Bo Chen, Rui Mao, Hongjie Wang & Jin-Xiong She
Pages: 49-55
Published online: 19 Feb 2023
AbstractforCell line and drug-dependent effect of ERBB3 on cancer cell proliferation, chemosensitivity, and multidrug actions | References | PDF (898.9 KB)
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Open Access

Other

A novel cell-based 384-well, label-free assay for discovery of inhibitors of influenza A virus
Fuli Jia, Clinton Maddox, Alice Gao, Louie Tran, William Severson, E Lucile White, Lynn Rasmussen, Anju Dang & Colleen B Jonsson
Pages: 57-67
Published online: 19 Feb 2023
AbstractforA novel cell-based 384-well, label-free assay for discovery of inhibitors of influenza A virus | References | PDF (597.7 KB)
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Open Access

Original Research

Article
Development of a high throughput screening assay for inhibitors of hedgehog-heparin interactions
Laura R Daye, Willietta Gibson & Kevin P Williams
Pages: 69-80
Published online: 19 Feb 2023
AbstractforDevelopment of a high throughput screening assay for inhibitors of hedgehog-heparin interactions | References | PDF (439.2 KB)
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Open Access
Article
Comparison of the efficiencies of two TR-FRET methods to detect in vitro natural and synthesized inhibitors of the Raf/MEK/ERK signaling pathway
Fabienne Saab, Sylvain Routier, Jean-Yves Mérour, Valérie Bénéteau & Françoise Schoentgen
Pages: 81-98
Published online: 19 Feb 2023
AbstractforComparison of the efficiencies of two TR-FRET methods to detect in vitro natural and synthesized inhibitors of the Raf/MEK/ERK signaling pathway | References | PDF (557.6 KB)
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Open Access

Methodology

Quantitative analysis of aggregation-solubility relationship by in-silico solubility prediction
Tadaaki Mashimo, Yoshifumi Fukunishi, Masaya Orita, Naoko Katayama, Shigeo Fujita & Haruki Nakamura
Pages: 99-107
Published online: 19 Feb 2023
AbstractforQuantitative analysis of aggregation-solubility relationship by in-silico solubility prediction | References | PDF (260.8 KB)
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Open Access

Original Research

Article
In vitro screening and structural characterization of inhibitors of the S100B-p53 interaction
Paul T Wilder, Thomas H Charpentier, Melissa A Liriano, Kira Gianni, Kristen M Varney, Edwin Pozharski, Andrew Coop, Eric A Toth, Alex D MacKerell & David J Weber
Pages: 109-126
Published online: 07 Jul 2010
AbstractforIn vitro screening and structural characterization of inhibitors of the S100B-p53 interaction | References | PDF (4.4 MB)
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Open Access
Article
High content screening for nonclassical peroxisome proliferators
Jonathan Z Sexton, Qingping He, Lawrence J Forsberg & Jay E Brenman
Pages: 127-140
Published online: 19 Feb 2023
AbstractforHigh content screening for nonclassical peroxisome proliferators | References | PDF (3.9 MB)
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Open Access

Review

Review Article
New developments and emerging trends in high-throughput screening methods for lead compound identification
James W Noah
Pages: 141-149
Published online: 04 Aug 2010
AbstractforNew developments and emerging trends in high-throughput screening methods for lead compound identification | References | PDF (151.6 KB)
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Open Access

Original Research

Article
Fission yeast as a HTS platform for molecular probes of HIV-1 Vpr-induced cell death
Zsigmond Benko, Robert T Elder, Dong Liang & Richard Y Zhao
Pages: 151-162
Published online: 19 Feb 2023
AbstractforFission yeast as a HTS platform for molecular probes of HIV-1 Vpr-induced cell death | References | PDF (2.4 MB)
  • 23 Views
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Open Access
Article
Development and validation of an RNAi screen for ABT-737 sensitizers
Kenneth W Yip, Inki Kim, Jason Garrison, Apple Cortez, Nancy Cheung, Pedro Aza-Blanc, Marina Konopleva, Michael Andreeff & John C Reed
Pages: 163-170
Published online: 19 Feb 2023
AbstractforDevelopment and validation of an RNAi screen for ABT-737 sensitizers | References | PDF (1.5 MB)
  • 11 Views
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Open Access

Review

Review Article
Endothelial vascular smooth muscle cell coculture assay for high throughput screening assays to identify antiangiogenic and other therapeutic molecules
George A Truskey
Pages: 171-181
Published online: 19 Feb 2023
AbstractforEndothelial vascular smooth muscle cell coculture assay for high throughput screening assays to identify antiangiogenic and other therapeutic molecules | References | PDF (1.1 MB)
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Open Access
Review Article
An overview of urinary proteomics applications in human diseases
Gayathri Gopalan, Veena S Rao & Vijay V Kakkar
Pages: 183-192
Published online: 19 Feb 2023
AbstractforAn overview of urinary proteomics applications in human diseases | References | PDF (193.5 KB)
  • 31 Views
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Open Access

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