Bioanalysis, Volume 10, Issue 9 (2018)

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Bioanalysis, Volume 10, Issue 9 (2018)

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Foreword

Introduction
Novel LC–MS Assays Impacting CYP and Transporter Drug–Drug Interaction Evaluations
Ragu Ramanathan
Pages: 609-613
Published online: 29 May 2018
First Page PreviewforNovel LC–MS Assays Impacting CYP and Transporter Drug–Drug Interaction Evaluations | Full Text | References | PDF (177.2 KB)
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Commentary

Editorial
Endogenous Probes for Human Liver Organic Anion-Transporting Polypeptides: The Intersection of Bioanalytical and ADME Science
A David Rodrigues
Pages: 615-618
Published online: 16 May 2018
First Page PreviewforEndogenous Probes for Human Liver Organic Anion-Transporting Polypeptides: The Intersection of Bioanalytical and ADME Science | Full Text | References | PDF (184 KB)
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Editorial
Application of in vitro CYP and Transporter Assays to Predict Clinical Drug–Drug Interactions
Donna A Volpe & Praveen V Balimane
Pages: 619-623
Published online: 16 May 2018
First Page PreviewforApplication of in vitro CYP and Transporter Assays to Predict Clinical Drug–Drug Interactions | Full Text | References | PDF (197.2 KB)
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Editorial
A Pharmaceutical Industry Perspective on Transporter and CYP-Mediated Drug–Drug Interactions: Kidney Transporter Biomarkers
Hong Shen
Pages: 625-631
Published online: 16 May 2018
First Page PreviewforA Pharmaceutical Industry Perspective on Transporter and CYP-Mediated Drug–Drug Interactions: Kidney Transporter Biomarkers | Full Text | References | PDF (222.4 KB)
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Methodology

Article
UHPLC–MS/MS Bioanalysis of Human Plasma Coproporphyrins as Potential Biomarkers for Organic Anion-Transporting Polypeptide-Mediated Drug Interactions
Hamza Kandoussi, Jianing Zeng, Kumar Shah, Patricia Paterson, Rasa Santockyte, Pathanjali Kadiyala, Hong Shen, Petia Shipkova, Robert Langish, Richard Burrrell, John Easter, Thomas Mariannino, Punit Marathe, Yurong Lai, Yan Zhang & Renuka Pillutla
Pages: 633-644
Published online: 11 May 2018
AbstractforUHPLC–MS/MS Bioanalysis of Human Plasma Coproporphyrins as Potential Biomarkers for Organic Anion-Transporting Polypeptide-Mediated Drug Interactions | Full Text | References | PDF (1 MB) | Supplemental
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Preliminary Communication

Brief Report
A Multiplex HRMS Assay for Quantifying Selected Human Plasma Bile Acids as Candidate OATP Biomarkers
Brian Rago, Brendan Tierney, A David Rodrigues, Christopher L Holliman & Ragu Ramanathan
Pages: 645-657
Published online: 11 May 2018
AbstractforA Multiplex HRMS Assay for Quantifying Selected Human Plasma Bile Acids as Candidate OATP Biomarkers | Full Text | References | PDF (959.9 KB) | Supplemental
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Brief Report
HPLC–high-Resolution Mass Spectrometry with Polarity Switching for Increasing Throughput of Human in vitro Cocktail Drug–Drug Interaction Assay
Ragu Ramanathan, Anima Ghosal, Lakshmi Ramanathan, Kate Comstock, Helen Shen & Dil Ramanathan
Pages: 659-672
Published online: 11 May 2018
AbstractforHPLC–high-Resolution Mass Spectrometry with Polarity Switching for Increasing Throughput of Human in vitro Cocktail Drug–Drug Interaction Assay | Full Text | References | PDF (1.9 MB)
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Research Article

Article
LC–MS/MS Assay for N1-Methylnicotinamide in Humans, an Endogenous Probe for Renal Transporters
Lina Luo, Jared Kay, Jenny Zhang, Christopher L Holliman, A David Rodrigues, Martin Dowty, Christopher Banfield & Ragu Ramanathan
Pages: 673-689
Published online: 11 May 2018
AbstractforLC–MS/MS Assay for N1-Methylnicotinamide in Humans, an Endogenous Probe for Renal Transporters | Full Text | References | PDF (984.5 KB) | Supplemental
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Article
A Fully Automated and Validated Human Plasma LC–MS/MS Assay for Endogenous OATP Biomarkers Coproporphyrin-I and Coproporphyrin-III
Amanda King-Ahmad, Sara Clemens, Ragu Ramanathan, Yanhua Zhang, Nancy Raha, Yizhong Zhang, Christopher Holliman, A David Rodrigues & Fumin Li
Pages: 691-701
Published online: 11 May 2018
AbstractforA Fully Automated and Validated Human Plasma LC–MS/MS Assay for Endogenous OATP Biomarkers Coproporphyrin-I and Coproporphyrin-III | Full Text | References | PDF (652.9 KB)
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