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Volume 2, Issue 3

Bioanalysis

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Bioanalysis, Volume 2, Issue 3 (2010)

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Bioanalysis, Volume 2, Issue 3 (2010)

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Vol 16, 2024 Vol 15, 2023 Vol 14, 2022 Vol 13, 2021 Vol 12, 2020 Vol 11, 2019 Vol 10, 2018 Vol 9, 2017 Vol 8, 2016 Vol 7, 2015 Vol 6, 2014 Vol 5, 2013 Vol 4, 2012 Vol 3, 2011 Volume 2, 2010 Vol 1, 2009

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Foreword

Introduction

Welcome to ‘Microdosing‘

RMJ Ings

Pages: 371-372

Published online: 16 Mar 2010

CitationforWelcome to ‘Microdosing‘ | Full Text | References | PDF (694 KB)

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Editorial

Human Microdosing for The Prediction of Patient Response

Paul T Henderson & Chong-xian Pan

Pages: 373-376

Published online: 16 Mar 2010

First Page PreviewforHuman Microdosing for The Prediction of Patient Response | Full Text | References | PDF (775.6 KB)

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Editorial

Trends in Microdosing and Other Exploratory Human Pharmacokinetic Studies for Early Drug Development

Berend Oosterhuis

Pages: 377-379

Published online: 16 Mar 2010

First Page PreviewforTrends in Microdosing and Other Exploratory Human Pharmacokinetic Studies for Early Drug Development | Full Text | References | PDF (832.1 KB)

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News & Analysis

News

News & Analysis

Pages: 381-384

Published online: 16 Mar 2010

First Page PreviewforNews & Analysis | Full Text | PDF (539 KB)

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Interview: News & Analysis

News

Interview with Professor Malcolm Rowland

Malcolm Rowland

Pages: 385-391

Published online: 16 Mar 2010

AbstractforInterview with Professor Malcolm Rowland | Full Text | References | PDF (549.3 KB)

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News & Analysis

News

Opinion: Microdosing: Safer Clinical Trials and Fewer Animal Tests

Gill Langley & Sebastien Farnaud

Pages: 393-395

Published online: 16 Mar 2010

First Page PreviewforOpinion: Microdosing: Safer Clinical Trials and Fewer Animal Tests | Full Text | References | PDF (1 MB)

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Methodology

Article

Development of 2D Chiral Chromatography with Accelerator Mass Spectrometry for Quantification of ¹⁴C-Labeled R- and S-Verapamil in Plasma

M Simpson, G Lappin & BJ Keely

Pages: 397-405

Published online: 16 Mar 2010

AbstractforDevelopment of 2D Chiral Chromatography with Accelerator Mass Spectrometry for Quantification of ¹⁴C-Labeled R- and S-Verapamil in Plasma | Full Text | References | PDF (874.1 KB)

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Research article

Article

Sensitivity and Proportionality Assessment of Metabolites from Microdose to High Dose in Rats Using LC–MS/MS

Jinsong Ni, Hui Ouyang, Carmai Seto, Takeo Sakuma, Robert Ellis, Josh Rowe, Andrew Acheampong, Devin Welty & Gabriella Szekely-Klepser

Pages: 407-419

Published online: 16 Mar 2010

AbstractforSensitivity and Proportionality Assessment of Metabolites from Microdose to High Dose in Rats Using LC–MS/MS | Full Text | References | PDF (1 MB)

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Review

Review Article

Microdosing in Early Lead Discovery

AP Jekunen, EKJ Pauwels & KJA Kairemo

Pages: 421-428

Published online: 16 Mar 2010

AbstractforMicrodosing in Early Lead Discovery | Full Text | References | PDF (695.3 KB)

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Review Article

Practical Experience of Using Human Microdosing with AMS Analysis to Obtain Early Human Drug Metabolism and PK Data

R Colin Garner

Pages: 429-440

Published online: 16 Mar 2010

AbstractforPractical Experience of Using Human Microdosing with AMS Analysis to Obtain Early Human Drug Metabolism and PK Data | Full Text | References | PDF (1.1 MB)

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Review Article

Early Human ADME Using Microdoses and Microtracers: Bioanalytical Considerations

Stephen R Dueker, Peter N Lohstroh, Jason A Giacomo, Le T Vuong, Bradly D Keck & John S Vogel

Pages: 441-454

Published online: 16 Mar 2010

AbstractforEarly Human ADME Using Microdoses and Microtracers: Bioanalytical Considerations | Full Text | References | PDF (2.5 MB)

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Review Article

Accelerator Mass Spectrometry Best Practices for Accuracy and Precision in Bioanalytical ¹⁴C Measurements

John S Vogel, Jason A Giacomo, Tim Schulze-König, Bradly D Keck, Peter Lohstroh & Stephen Dueker

Pages: 455-468

Published online: 16 Mar 2010

AbstractforAccelerator Mass Spectrometry Best Practices for Accuracy and Precision in Bioanalytical ¹⁴C Measurements | Full Text | References | PDF (2.5 MB)

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Review Article

Analytical Validation of Accelerator Mass Spectrometry for Pharmaceutical Development

Bradly D Keck, Ted Ognibene & John S Vogel

Pages: 469-485

Published online: 16 Mar 2010

AbstractforAnalytical Validation of Accelerator Mass Spectrometry for Pharmaceutical Development | Full Text | References | PDF (2.4 MB)

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Review Article

Ocular Microdialysis: A Continuous Sampling Technique to Study Pharmacokinetics and Pharmacodynamics in The Eye

Sai HS Boddu, Sriram Gunda, Ravinder Earla & Ashim K Mitra

Pages: 487-507

Published online: 16 Mar 2010

AbstractforOcular Microdialysis: A Continuous Sampling Technique to Study Pharmacokinetics and Pharmacodynamics in The Eye | Full Text | References | PDF (1.3 MB)

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Perspective

Review Article

Microdosing: Current and The Future

Graham Lappin

Pages: 509-517

Published online: 16 Mar 2010

AbstractforMicrodosing: Current and The Future | Full Text | References | PDF (940.1 KB)

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Review Article

Accelerator Mass Spectrometry-Enabled Studies: Current Status and Future Prospects

Ali Arjomand

Pages: 519-541

Published online: 16 Mar 2010

AbstractforAccelerator Mass Spectrometry-Enabled Studies: Current Status and Future Prospects | Full Text | References | PDF (2.7 MB)

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Obituary

Obituary: Dr Michael Stephen Moss

Phil Teale

Page: 543

Published online: 16 Mar 2010

CitationforObituary: Dr Michael Stephen Moss | Full Text | PDF (429.3 KB)

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Acknowledgements

Page: 551

Published online: 16 Mar 2010

CitationforAcknowledgements | Full Text | PDF (145.3 KB)

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