Drug Metabolism Reviews, Volume 15, Issue 1-2 (1984)

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Drug Metabolism Reviews, Volume 15, Issue 1-2 (1984)

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Research Article

Article
Frontiers in Pharmacokinetic Data Analysis: Introduction
R. L. Galeazzi, R. Brandt, H. Eckert, P. H. Hinderling, W. Reiss Ciba-Geigy & S. Vozeh
Page: 1
Published online: 22 Sep 2008
CitationforFrontiers in Pharmacokinetic Data Analysis: Introduction | PDF (39.7 KB)
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Article
Advantages and Limitations of Different Kinetic Models
Page: 3
Published online: 22 Sep 2008
CitationforAdvantages and Limitations of Different Kinetic Models | PDF (6.6 KB)
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Article
Advantages and Limitations of Different Kinetic Models: Introduction
Page: 5
Published online: 22 Sep 2008
CitationforAdvantages and Limitations of Different Kinetic Models: Introduction | PDF (31.4 KB)
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Article
Relevance, Experiences, and Trends in the Use of Compartmental Models
Giorgio Segre
Pages: 7-53
Published online: 22 Sep 2008
First Page PreviewforRelevance, Experiences, and Trends in the Use of Compartmental Models | References | PDF (1.4 MB)
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Article
Physiologic Pharmacokinetic Models: Relevance, Experience, and Future Trends
Malcolm Rowland
Pages: 55-74
Published online: 22 Sep 2008
First Page PreviewforPhysiologic Pharmacokinetic Models: Relevance, Experience, and Future Trends | References | PDF (799.9 KB)
  • 42 Views
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Article
Applicability of Different Types of Models in Health and Disease
Luc Balant
Pages: 75-102
Published online: 22 Sep 2008
First Page PreviewforApplicability of Different Types of Models in Health and Disease | References | PDF (978.5 KB)
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Article
Noncompartmental Approach in Pharmacokinetics Using Moments
Erich A. Nüesch
Pages: 103-131
Published online: 22 Sep 2008
First Page PreviewforNoncompartmental Approach in Pharmacokinetics Using Moments | References | PDF (871.5 KB)
  • 38 Views
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Article
The Problem of Choosing Weights in Nonlinear Regression Analysis of Pharmacokinetic Data
Carl C. Peck, Lewis B. Sheiner & Alice I. Nichols
Pages: 133-148
Published online: 22 Sep 2008
First Page PreviewforThe Problem of Choosing Weights in Nonlinear Regression Analysis of Pharmacokinetic Data | References | PDF (681.9 KB)
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Article
Population Pharmacokinetics: Introduction
Page: 151
Published online: 22 Sep 2008
CitationforPopulation Pharmacokinetics: Introduction | PDF (55 KB)
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Free Access
Article
The Population Approach to Pharmacokinetic Data Analysis: Rationale and Standard Data Analysis Methods
Lewis B. Sheiner
Pages: 153-171
Published online: 22 Sep 2008
AbstractforThe Population Approach to Pharmacokinetic Data Analysis: Rationale and Standard Data Analysis Methods | References | PDF (882.7 KB)
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Article
1. Population Pharmacokinetic Data and Parameter Estimation Based on Their First Two Statistical Moments
Stuart L. Beal
Pages: 173-193
Published online: 22 Sep 2008
Abstractfor1. Population Pharmacokinetic Data and Parameter Estimation Based on Their First Two Statistical Moments | References | PDF (981.8 KB)
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Article
Estimation of Population Pharmacokinetic Parameters Using Destructively Obtained Experimental Data: A Simulation Study of the One-Compartment Open Model
F. Tom Lindstrom & David S. Birkes
Pages: 195-264
Published online: 22 Sep 2008
AbstractforEstimation of Population Pharmacokinetic Parameters Using Destructively Obtained Experimental Data: A Simulation Study of the One-Compartment Open Model | References | PDF (2.3 MB)
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Article
Alternative Approaches to Estimation of Population Pharmacokinetic Parameters: Comparison with the Nonlinear Mixed-Effect Model
Jean-Louis Steimer, Alain Mallet, Jean-Louis Golmard & Jean-François Boisvieux
Pages: 265-292
Published online: 22 Sep 2008
AbstractforAlternative Approaches to Estimation of Population Pharmacokinetic Parameters: Comparison with the Nonlinear Mixed-Effect Model | References | PDF (1.3 MB)
  • 405 Views
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Article
Experience with Nonmem: Analysis of Routine Phenytoin Clinical Pharmacokinetic Data
Lewis B. Sheiner & Thaddeus H. Grasela
Pages: 293-303
Published online: 22 Sep 2008
AbstractforExperience with Nonmem: Analysis of Routine Phenytoin Clinical Pharmacokinetic Data | References | PDF (460.6 KB)
  • 61 Views
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Article
2. Experience with Nonmem: Analysis of Serum Concentration Data in Patients Treated with Mexiletine and Lidocaine
S. Vozeh, M. Wenk & F. Follath
Pages: 305-315
Published online: 22 Sep 2008
Abstractfor2. Experience with Nonmem: Analysis of Serum Concentration Data in Patients Treated with Mexiletine and Lidocaine | References | PDF (394.9 KB)
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Article
Experiences in the Application of NONMEM to Pharmacokinetic Data Analysis
H. Flühler, H. Huber, E. Widmer & S. Brechbühler
Pages: 317-339
Published online: 22 Sep 2008
AbstractforExperiences in the Application of NONMEM to Pharmacokinetic Data Analysis | References | PDF (665.4 KB)
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Article
Pharmacokinetics and Pharmacodynamics: Introduction
Pages: 343-344
Published online: 22 Sep 2008
CitationforPharmacokinetics and Pharmacodynamics: Introduction | PDF (69 KB)
  • 21 Views
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Article
Receptor Theories and Quantitative Effect Versus Dose-Concentration Relationship
R. J. Tallarida
Pages: 345-363
Published online: 22 Sep 2008
AbstractforReceptor Theories and Quantitative Effect Versus Dose-Concentration Relationship | References | PDF (741 KB)
  • 21 Views
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Article
Quantitative Relationships between Dynamics and Kinetics of Drugs: A Systems Dynamics Approach
J. M. Van Rossum & J. P. T. Burgers
Pages: 365-382
Published online: 22 Sep 2008
AbstractforQuantitative Relationships between Dynamics and Kinetics of Drugs: A Systems Dynamics Approach | References | PDF (710.4 KB)
  • 24 Views
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Article
Integrated Pharmacokinetic-Dynamic Modeling of Drugs Acting on the CNS
Lennart K. Paalzow
Pages: 383-400
Published online: 22 Sep 2008
AbstractforIntegrated Pharmacokinetic-Dynamic Modeling of Drugs Acting on the CNS | References | PDF (597.7 KB)
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