Drug Metabolism Reviews, Volume 31, Issue 1 (1999)

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Drug Metabolism Reviews, Volume 31, Issue 1 (1999)

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Research Article

Article
THE VANDERBILT UNIVERSITY CENTER IN MOLECULAR TOXICOLOGY: THE FIRST 30 YEARS
F. PETER GUENGERICH
Pages: 1-11
Published online: 02 Aug 1999
First Page PreviewforTHE VANDERBILT UNIVERSITY CENTER IN MOLECULAR TOXICOLOGY: THE FIRST 30 YEARS | Full Text | References | PDF (781 KB)
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Article
PREDICTING DRUG INTERACTIONS AND PHARMACOKINETIC VARIABILITY WITH IN VITRO METHODS: THE OLANZAPINE EXPERIENCE*
STEVEN A. WRIGHTON & BARBARA J. RING
Pages: 15-28
Published online: 02 Aug 1999
First Page PreviewforPREDICTING DRUG INTERACTIONS AND PHARMACOKINETIC VARIABILITY WITH IN VITRO METHODS: THE OLANZAPINE EXPERIENCE* | Full Text | References | PDF (82.2 KB)
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Article
MODULATION OF DRUG METABOLISM IN INFECTIOUS AND INFLAMMATORY DISEASES*
HEINRICH IBER, MARION B. SEWER, THOMAS B. BARCLAY, STEPHANIE R. MITCHELL, TONG LI & EDWARD T. MORGAN
Pages: 29-41
Published online: 02 Aug 1999
First Page PreviewforMODULATION OF DRUG METABOLISM IN INFECTIOUS AND INFLAMMATORY DISEASES* | Full Text | References | PDF (90.3 KB)
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Article
MODELING THE CHEMOPROTECTIVE FUNCTIONS OF GLUTATHIONE S-TRANSFERASES IN CULTURED CELL LINES BY HETEROLOGOUS EXPRESSION*
ALAN J. TOWNSEND, WANDA R. FIELDS, AMANDA J. DOSS, MARGIE L. CLAPPER, JOHANNES DOEHMER & CHARLES S. MORROW
Pages: 43-69
Published online: 02 Aug 1999
First Page PreviewforMODELING THE CHEMOPROTECTIVE FUNCTIONS OF GLUTATHIONE S-TRANSFERASES IN CULTURED CELL LINES BY HETEROLOGOUS EXPRESSION* | Full Text | References | PDF (210.2 KB)
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Article
KINETIC AND CHEMICAL MECHANISM OF EPOXIDE HYDROLASE*
RICHARD N. ARMSTRONG
Pages: 71-86
Published online: 02 Aug 1999
First Page PreviewforKINETIC AND CHEMICAL MECHANISM OF EPOXIDE HYDROLASE* | Full Text | References | PDF (103.8 KB)
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Article
ROLE OF KUPFFER CELLS IN PEROXISOME PROLIFERATOR-INDUCED HEPATOCYTE PROLIFERATION*
MICHELLE L. ROSE, IVAN RUSYN, HEIDI K. BOJES, DORI R. GERMOLEC, MICHAEL LUSTER & RONALD G. THURMAN
Pages: 87-116
Published online: 02 Aug 1999
First Page PreviewforROLE OF KUPFFER CELLS IN PEROXISOME PROLIFERATOR-INDUCED HEPATOCYTE PROLIFERATION* | Full Text | References | PDF (234.9 KB)
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Article
THE ISOPROSTANES: UNIQUE PROSTAGLANDIN-LIKE PRODUCTS OF FREE-RADICAL-INITIATED LIPID PEROXIDATION*
JASON D. MORROW, YAN CHEN, CYNTHIA J. BRAME, JAMES YANG, STEPHANIE C. SANCHEZ, JEFFREY XU, WILLIAM E. ZACKERT, JOSEPH A. AWAD & L. JACKSON ROBERTS
Pages: 117-139
Published online: 02 Aug 1999
First Page PreviewforTHE ISOPROSTANES: UNIQUE PROSTAGLANDIN-LIKE PRODUCTS OF FREE-RADICAL-INITIATED LIPID PEROXIDATION* | Full Text | References | PDF (127.3 KB)
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Article
KINETICS OF HYDROLYSIS AND REACTION OF AFLATOXIN B1EXO-8,9-EPOXIDE AND RELEVANCE TO TOXICITY AND DETOXICATION*,†
F. PETER GUENGERICH & WILLIAM W. JOHNSON
Pages: 141-158
Published online: 02 Aug 1999
First Page PreviewforKINETICS OF HYDROLYSIS AND REACTION OF AFLATOXIN B1EXO-8,9-EPOXIDE AND RELEVANCE TO TOXICITY AND DETOXICATION*,† | Full Text | References | PDF (144 KB)
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Article
STRATEGIES TO ENHANCE THE COEXPRESSION OF CYTOCHROME P450 2E1 AND REDUCTASE IN BACTERIA*
TODD D. PORTER & SHINYU CHANG
Pages: 159-174
Published online: 02 Aug 1999
First Page PreviewforSTRATEGIES TO ENHANCE THE COEXPRESSION OF CYTOCHROME P450 2E1 AND REDUCTASE IN BACTERIA* | Full Text | References | PDF (345.5 KB)
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Article
THE MECHANISM OF BIOACTIVATION OF N-NITROSODIETHANOLAMINE*
RICHARD N. LOEPPKY
Pages: 175-193
Published online: 02 Aug 1999
First Page PreviewforTHE MECHANISM OF BIOACTIVATION OF N-NITROSODIETHANOLAMINE* | Full Text | References | PDF (155.5 KB)
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Article
FLAVODOXIN AS A MODEL FOR THE P450-INTERACTING DOMAIN OF NADPH CYTOCHROME P450 REDUCTASE*
CHRISTOPHER M. JENKINS & MICHAEL R. WATERMAN
Pages: 195-203
Published online: 02 Aug 1999
First Page PreviewforFLAVODOXIN AS A MODEL FOR THE P450-INTERACTING DOMAIN OF NADPH CYTOCHROME P450 REDUCTASE* | Full Text | References | PDF (73.3 KB)
  • 97 Views
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Article
P450 SUBFAMILY CYP2J AND THEIR ROLE IN THE BIOACTIVATION OF ARACHIDONIC ACID IN EXTRAHEPATIC TISSUES*
PAULA E. SCARBOROUGH, JIXIANG MA, WEI QU & DARRYL C. ZELDIN
Pages: 205-234
Published online: 02 Aug 1999
AbstractforP450 SUBFAMILY CYP2J AND THEIR ROLE IN THE BIOACTIVATION OF ARACHIDONIC ACID IN EXTRAHEPATIC TISSUES* | Full Text | References | PDF (225.5 KB)
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Article
BENZYLAMINE ANALOG BINDING STUDIES AS PROBES OF THE SUBSTRATE SITES OF MONOAMINE OXIDASES A AND B*
DALE E. EDMONDSON
Pages: 235-245
Published online: 02 Aug 1999
First Page PreviewforBENZYLAMINE ANALOG BINDING STUDIES AS PROBES OF THE SUBSTRATE SITES OF MONOAMINE OXIDASES A AND B* | Full Text | References | PDF (68.5 KB)
  • 57 Views
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Article
ROLE OF CANONICAL GLUCOCORTICOID RESPONSIVE ELEMENTS IN MODULATING EXPRESSION OF GENES REGULATED BY THE ARYLHYDROCARBON RECEPTOR*
M. W. LINDER, K. C. FALKNER, G. SRINIVASAN, R. N. HINES & R. A. PROUGH
Pages: 247-271
Published online: 02 Aug 1999
First Page PreviewforROLE OF CANONICAL GLUCOCORTICOID RESPONSIVE ELEMENTS IN MODULATING EXPRESSION OF GENES REGULATED BY THE ARYLHYDROCARBON RECEPTOR* | Full Text | References | PDF (756.6 KB)
  • 67 Views
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Article
REACTIONS OF PROSTAGLANDIN ENDOPEROXIDE SYNTHASE WITH NITRIC OXIDE AND PEROXYNITRITE*
DOUGLAS C. GOODWIN, LISA M. LANDINO & LAWRENCE J. MARNETT
Pages: 273-294
Published online: 02 Aug 1999
First Page PreviewforREACTIONS OF PROSTAGLANDIN ENDOPEROXIDE SYNTHASE WITH NITRIC OXIDE AND PEROXYNITRITE* | Full Text | References | PDF (1.1 MB)
  • 41 Views
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