Expert Opinion on Drug Discovery, Volume 14, Issue 6 (2019)

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Expert Opinion on Drug Discovery, Volume 14, Issue 6 (2019)

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Editorial

Editorial
Are animal models a necessity for acute radiation syndrome drug discovery?
Dörthe Schaue & William H. McBride
Pages: 511-515
Published online: 14 Mar 2019
First Page PreviewforAre animal models a necessity for acute radiation syndrome drug discovery? | Full Text | References | PDF (485 KB) | EPUB
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Editorial
Duality of activity cliffs in drug discovery
Jürgen Bajorath
Pages: 517-520
Published online: 18 Mar 2019
First Page PreviewforDuality of activity cliffs in drug discovery | Full Text | References | PDF (514.4 KB) | EPUB
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Perspective

Article
The impact of decreasing biodiversity on novel drug discovery: is there a serious cause for concern?
David J. Newman
Pages: 521-525
Published online: 22 Mar 2019
AbstractforThe impact of decreasing biodiversity on novel drug discovery: is there a serious cause for concern? | Full Text | References | PDF (458.9 KB) | EPUB
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Review

Review
The problem of racemization in drug discovery and tools to predict it
Andrew Ballard, Stefania Narduolo, Hiwa O. Ahmad, David A. Cosgrove, Andrew G. Leach & Niklaas J. Buurma
Pages: 527-539
Published online: 18 Mar 2019
AbstractforThe problem of racemization in drug discovery and tools to predict it | Full Text | References | PDF (2.7 MB) | EPUB
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Review
Drugs that target aging: how do we discover them?
A Myers & GJ Lithgow
Pages: 541-548
Published online: 11 Apr 2019
AbstractforDrugs that target aging: how do we discover them? | Full Text | References | PDF (825.9 KB) | EPUB
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Review
How can we develop better antispasmodics for irritable bowel syndrome?
Sheyda Ranjbar, Seyed Afshin Seyednejad, Shekoufeh Nikfar, Roja Rahimi & Mohammad Abdollahi
Pages: 549-562
Published online: 28 Mar 2019
AbstractforHow can we develop better antispasmodics for irritable bowel syndrome? | Full Text | References | PDF (1.7 MB) | EPUB
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Review
Discovery of natural products with metal-binding properties as promising antibacterial agents
Prasad Dandawate, Subhash Padhye, Rainer Schobert & Bernhard Biersack
Pages: 563-576
Published online: 25 Mar 2019
AbstractforDiscovery of natural products with metal-binding properties as promising antibacterial agents | Full Text | References | PDF (1.9 MB) | EPUB
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Review
Developing animal models of Zika virus infection for novel drug discovery
Cristine Marie Yde Ohki, Cecilia Benazzato, Fabiele Baldino Russo & Patricia Cristina Baleeiro Beltrão-Braga
Pages: 577-589
Published online: 16 Apr 2019
AbstractforDeveloping animal models of Zika virus infection for novel drug discovery | Full Text | References | PDF (1.2 MB) | EPUB
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Review
The discovery and development of inhaled therapeutics for migraine
Nicolas Vandenbussche & Peter J Goadsby
Pages: 591-599
Published online: 29 Mar 2019
AbstractforThe discovery and development of inhaled therapeutics for migraine | Full Text | References | PDF (711.9 KB) | EPUB
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