Expert Opinion on Drug Discovery, Volume 18, Issue 8 (2023)

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Expert Opinion on Drug Discovery, Volume 18, Issue 8 (2023)

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Editorial

Editorial
What are the current trends in G protein-coupled receptor targeted drug discovery?
Vicent Casadó & Verònica Casadó-Anguera
Pages: 815-820
Published online: 19 May 2023
First Page PreviewforWhat are the current trends in G protein-coupled receptor targeted drug discovery? | Full Text | References | PDF (1.5 MB) | EPUB
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Technology Evaluation

Report
MEDIATE - Molecular DockIng at homE: Turning collaborative simulations into therapeutic solutions
Giulio Vistoli, Candida Manelfi, Carmine Talarico, Anna Fava, Arieh Warshel, Igor V. Tetko, Rossen Apostolov, Yang Ye, Chiara Latini, Federico Ficarelli, Gianluca Palermo, Davide Gadioli, Emanuele Vitali, Gaetano Varriale, Vincenzo Pisapia, Marco Scaturro, Silvano Coletti, Daniele Gregori, Daniel Gruffat, Edgardo Leija, Sam Hessenauer, Alberto Delbianco, Marcello Allegretti & Andrea R. Beccari
Pages: 821-833
Published online: 10 Jul 2023
AbstractforMEDIATE - Molecular DockIng at homE: Turning collaborative simulations into therapeutic solutions | Full Text | References | PDF (3.1 MB) | EPUB
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Open Access

Review

Review Article
New directions in psychiatric drug development: promising therapeutics in the pipeline
Linda S. Brady, Sarah H. Lisanby & Joshua A. Gordon
Pages: 835-850
Published online: 23 Jun 2023
AbstractforNew directions in psychiatric drug development: promising therapeutics in the pipeline | Full Text | References | PDF (403.4 KB) | EPUB
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Review Article
Nature as a source and inspiration for human monoamine oxidase B (hMAO-B) inhibition: A review of the recent advances in chemical modification of natural compounds
Francesco Melfi, Simone Carradori, Andrea Angeli & Ilaria D’Agostino
Pages: 851-879
Published online: 23 Jun 2023
AbstractforNature as a source and inspiration for human monoamine oxidase B (hMAO-B) inhibition: A review of the recent advances in chemical modification of natural compounds | Full Text | References | PDF (7.4 MB) | EPUB
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Review Article
Thermodynamic and kinetic approaches for drug discovery to target protein misfolding and aggregation
Michele Vendruscolo
Pages: 881-891
Published online: 05 Jun 2023
AbstractforThermodynamic and kinetic approaches for drug discovery to target protein misfolding and aggregation | Full Text | References | PDF (3.4 MB) | EPUB
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Open Access
Review Article
Understanding circadian dynamics: current progress and future directions for chronobiology in drug discovery
Meltem Weger, Benjamin D. Weger & Frédéric Gachon
Pages: 893-901
Published online: 13 Jun 2023
AbstractforUnderstanding circadian dynamics: current progress and future directions for chronobiology in drug discovery | Full Text | References | PDF (1.4 MB) | EPUB
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Article
Virtual screening and zebrafish models in tandem, for drug discovery and development
David Hernández-Silva, Francisca Alcaraz-Pérez, Horacio Pérez-Sánchez & Maria Luisa Cayuela
Pages: 903-915
Published online: 30 Nov 2022
AbstractforVirtual screening and zebrafish models in tandem, for drug discovery and development | Full Text | References | PDF (2 MB) | EPUB
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Review Article
Novel targets and inhibitors of the Mycobacterium tuberculosis cytochrome bd oxidase to foster anti-tuberculosis drug discovery
Amaravadhi Harikishore, Vikneswaran Mathiyazakan, Kevin Pethe & Gerhard Grüber
Pages: 917-927
Published online: 18 Jun 2023
AbstractforNovel targets and inhibitors of the Mycobacterium tuberculosis cytochrome bd oxidase to foster anti-tuberculosis drug discovery | Full Text | References | PDF (5.4 MB) | EPUB | Supplemental
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Review Article
Targeted Degradation of Structured RNAs via Ribonuclease-Targeting Chimeras (RiboTacs)
Salma Haj-Yahia, Arijit Nandi & Raphael I. Benhamou
Pages: 929-942
Published online: 20 Jun 2023
AbstractforTargeted Degradation of Structured RNAs via Ribonuclease-Targeting Chimeras (RiboTacs) | Full Text | References | PDF (6.5 MB) | EPUB
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