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Volume 3, Issue 12

Expert Opinion on Drug Discovery

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Expert Opinion on Drug Discovery, Volume 3, Issue 12 (2008)

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Expert Opinion on Drug Discovery, Volume 3, Issue 12 (2008)

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Perspectives

Article

Computational approaches in chemogenomics and chemical biology: current and future impact on drug discovery

Jürgen Bajorath

Pages: 1371-1376

Published online: 01 Dec 2008

AbstractforComputational approaches in chemogenomics and chemical biology: current and future impact on drug discovery | Full Text | References | PDF (274.8 KB)

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20 CrossRef citations
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Article

Can in vitro assessment provide relevant end points for cognitive drug programs?

Benedict C Albensi (Assistant Professor, Department of Pharmacology & Therapeutics, Associate Professor, Application Pending, Principal Investigator – St. Boniface Research Centre) PhD

Pages: 1377-1382

Published online: 01 Dec 2008

AbstractforCan in vitro assessment provide relevant end points for cognitive drug programs? | Full Text | References | PDF (283.8 KB)

49 Views
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Reviews

Article

Invertebrate and fungal model organisms: emerging platforms for drug discovery

Geoff E Stilwell & Bethany Westlund

Pages: 1383-1395

Published online: 01 Dec 2008

AbstractforInvertebrate and fungal model organisms: emerging platforms for drug discovery | Full Text | References | PDF (345.5 KB)

60 Views
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Article

An update on hybrid drugs in cardiovascular drug research

Vincenzo Calderone

Pages: 1397-1408

Published online: 01 Dec 2008

AbstractforAn update on hybrid drugs in cardiovascular drug research | Full Text | References | PDF (342 KB)

53 Views
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Article

Small-molecule inhibitors binding to protein kinases. Part I: exceptions from the traditional pharmacophore approach of type I inhibition

AC Backes PhD, B Zech PhD, B Felber PhD, B Klebl PhD & G Müller PhD

Pages: 1409-1425

Published online: 01 Dec 2008

AbstractforSmall-molecule inhibitors binding to protein kinases. Part I: exceptions from the traditional pharmacophore approach of type I inhibition | Full Text | References | PDF (2.8 MB)

607 Views
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Article

Small-molecule inhibitors binding to protein kinase. Part II: the novel pharmacophore approach of type II and type III inhibition

AC Backes PhD, B Zech PhD, B Felber PhD, B Klebl PhD & G Müller PhD

Pages: 1427-1449

Published online: 01 Dec 2008

AbstractforSmall-molecule inhibitors binding to protein kinase. Part II: the novel pharmacophore approach of type II and type III inhibition | Full Text | References | PDF (2.4 MB)

677 Views
90 CrossRef citations
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Article

Potential of zebrafish for anticancer drug screening

Leonard I Zon MD & Xiuning Le

Pages: 1451-1460

Published online: 01 Dec 2008

AbstractforPotential of zebrafish for anticancer drug screening | Full Text | References | PDF (3.3 MB)

156 Views
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Article

Current status of HTRF^® technology in kinase assays

Yong Jia PhD

Pages: 1461-1474

Published online: 01 Dec 2008

AbstractforCurrent status of HTRF^® technology in kinase assays | Full Text | References | PDF (459.8 KB)

444 Views
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