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Volume 3, Issue 7

Expert Opinion on Drug Discovery

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Expert Opinion on Drug Discovery, Volume 3, Issue 7 (2008)

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Expert Opinion on Drug Discovery, Volume 3, Issue 7 (2008)

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Editorial

Article

Designing safe drugs: what to consider?

Jeffrey A Kramer

Pages: 707-713

Published online: 23 Jun 2008

AbstractforDesigning safe drugs: what to consider? | Full Text | References | PDF (250.2 KB)

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Perspectives

Article

The industrialisation of cellular screening

Stephen Rees & Alan Wise

Pages: 715-723

Published online: 23 Jun 2008

AbstractforThe industrialisation of cellular screening | Full Text | References | PDF (583.8 KB)

99 Views
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Article

Clinical relevance of predictive physiologically based pharmacokinetic methods

Simon Thomas PhD

Pages: 725-732

Published online: 23 Jun 2008

AbstractforClinical relevance of predictive physiologically based pharmacokinetic methods | Full Text | References | PDF (367.8 KB)

99 Views
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Reviews

Article

Lead generation: reality check on commonly held views

Nader Fotouhi PhD, Paul Gillespie PhD & Robert Goodnow, Jr. PhD

Pages: 733-744

Published online: 23 Jun 2008

AbstractforLead generation: reality check on commonly held views | Full Text | References | PDF (455.6 KB)

124 Views
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Article

Non-cholinergic drug development for Alzheimer's disease

Roy Yaari MD, Shubha Kumar MD & Pierre N Tariot MD

Pages: 745-760

Published online: 23 Jun 2008

AbstractforNon-cholinergic drug development for Alzheimer's disease | Full Text | References | PDF (332.2 KB)

61 Views
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Article

Non-ATP-competitive kinase inhibitors – enhancing selectivity through new inhibition strategies

Stephen Harrison PhD, Kanad Das PhD, Felix Karim PhD, Derek Maclean PhD & Dirk Mendel PhD

Pages: 761-774

Published online: 23 Jun 2008

AbstractforNon-ATP-competitive kinase inhibitors – enhancing selectivity through new inhibition strategies | Full Text | References | PDF (1,006.3 KB)

273 Views
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Article

Second generation HIV protease inhibitors against resistant virus

Zhijian Lu PhD

Pages: 775-786

Published online: 23 Jun 2008

AbstractforSecond generation HIV protease inhibitors against resistant virus | Full Text | References | PDF (1.1 MB)

181 Views
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Article

CRAC inhibitors: identification and potential

Isabella Derler, Reinhard Fritsch, Rainer Schindl & Christoph Romanin PhD

Pages: 787-800

Published online: 23 Jun 2008

AbstractforCRAC inhibitors: identification and potential | Full Text | References | PDF (4.8 MB)

313 Views
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Article

New small-molecule inhibitors of mitogen-activated protein kinase kinase

Julie A Spicer

Pages: 801-817

Published online: 23 Jun 2008

AbstractforNew small-molecule inhibitors of mitogen-activated protein kinase kinase | Full Text | References | PDF (387.5 KB)

95 Views
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Technology Evaluation

Article

Alternative assay formats to identify diverse inhibitors of protein kinases

Pirthipal Singh & Walter HJ Ward

Pages: 819-831

Published online: 23 Jun 2008

AbstractforAlternative assay formats to identify diverse inhibitors of protein kinases | Full Text | References | PDF (672.4 KB)

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Expert Opinion on Drug Discovery (Vol.3, Iss.7, 2008)

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