Expert Opinion on Drug Discovery, Volume 4, Issue 8 (2009)

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Expert Opinion on Drug Discovery, Volume 4, Issue 8 (2009)

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Reviews

Article
Implications of endoplasmic reticulum stress, the unfolded protein response and apoptosis for molecular cancer therapy. Part I: targeting p53, Mdm2, GADD153/CHOP, GRP78/BiP and heat shock proteins
Donavon C Hiss MSc (Med) PhD (Med) & Gary A Gabriels MSc (Med)
Pages: 799-821
Published online: 10 Jun 2009
AbstractforImplications of endoplasmic reticulum stress, the unfolded protein response and apoptosis for molecular cancer therapy. Part I: targeting p53, Mdm2, GADD153/CHOP, GRP78/BiP and heat shock proteins | Full Text | References | PDF (705 KB)
  • 365 Views
  • 25 CrossRef citations
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Article
Design of small molecules targeting transcriptional activation by NF-κB: overview of recent advances
Daniel S Straus
Pages: 823-836
Published online: 22 Jul 2009
AbstractforDesign of small molecules targeting transcriptional activation by NF-κB: overview of recent advances | Full Text | References | PDF (746 KB)
  • 124 Views
  • 12 CrossRef citations
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Article
Model-based approaches to increase efficiency of drug development in schizophrenia: a can't miss opportunity
Gianluca Nucci, Roberto Gomeni & Italo Poggesi
Pages: 837-856
Published online: 24 Jun 2009
AbstractforModel-based approaches to increase efficiency of drug development in schizophrenia: a can't miss opportunity | Full Text | References | PDF (1 MB)
  • 218 Views
  • 24 CrossRef citations
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Article
Drug target central
Lee Harland & Anna Gaulton
Pages: 857-872
Published online: 22 Jul 2009
AbstractforDrug target central | Full Text | References | PDF (1.8 MB)
  • 237 Views
  • 12 CrossRef citations
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Article
The impact of hardware improvement for molecular modeling in a grid environment
Dandan Li, Ming Sun, Mingxiao Li, Zhibin Li & Zhenran Jiang
Pages: 873-877
Published online: 23 Jun 2009
AbstractforThe impact of hardware improvement for molecular modeling in a grid environment | Full Text | References | PDF (634.3 KB)
  • 29 Views
  • 1 CrossRef citations
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Article
The role of murine models of prostate cancer in drug target discovery and validation
Imran Ahmad, Owen J Sansom & Hing Y Leung
Pages: 879-888
Published online: 22 Jul 2009
AbstractforThe role of murine models of prostate cancer in drug target discovery and validation | Full Text | References | PDF (1.2 MB)
  • 102 Views
  • 6 CrossRef citations
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Article
Applications of fiber-optics-based nanosensors to drug discovery
Tuan Vo-Dinh, Jonathan Scaffidi, Molly Gregas, Yan Zhang & Victoria Seewaldt
Pages: 889-900
Published online: 22 Jul 2009
AbstractforApplications of fiber-optics-based nanosensors to drug discovery | Full Text | References | PDF (2.7 MB)
  • 112 Views
  • 13 CrossRef citations
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