Expert Opinion on Drug Discovery, Volume 5, Issue 4 (2010)

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Expert Opinion on Drug Discovery, Volume 5, Issue 4 (2010)

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Perspective

Article
The dynamics of drug-target interactions: drug-target residence time and its impact on efficacy and safety
Robert A Copeland
Pages: 305-310
Published online: 29 Mar 2010
AbstractforThe dynamics of drug-target interactions: drug-target residence time and its impact on efficacy and safety | Full Text | References | PDF (358.2 KB)
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Reviews

Article
The current role of model-based drug development
Satyendra Suryawanshi PhD, Liping Zhang PhD, Marc Pfister MD & Bernd Meibohm PhD FCP
Pages: 311-321
Published online: 29 Mar 2010
AbstractforThe current role of model-based drug development | Full Text | References | PDF (373.1 KB)
  • 358 Views
  • 26 CrossRef citations
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Article
Mining protein lists from proteomics studies: applications for drug discovery
Alexey V Antonov (Senior Scientist) PhD
Pages: 323-331
Published online: 29 Mar 2010
AbstractforMining protein lists from proteomics studies: applications for drug discovery | Full Text | References | PDF (196.7 KB)
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Article
The GRID/CPCA approach in drug discovery
Josmar R Rocha, Renato F Freitas & Carlos A Montanari
Pages: 333-346
Published online: 29 Mar 2010
AbstractforThe GRID/CPCA approach in drug discovery | Full Text | References | PDF (524.3 KB)
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Article
Tackling the challenges posed by target flexibility in drug design
Christian Beier & Martin Zacharias
Pages: 347-359
Published online: 29 Mar 2010
AbstractforTackling the challenges posed by target flexibility in drug design | Full Text | References | PDF (493.9 KB)
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Article
Use of phage display technology for the determination of the targets for small-molecule therapeutics
Yoichi Takakusagi, Kaori Takakusagi, Fumio Sugawara & Kengo Sakaguchi
Pages: 361-389
Published online: 29 Mar 2010
AbstractforUse of phage display technology for the determination of the targets for small-molecule therapeutics | Full Text | References | PDF (1.1 MB)
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Article
Platforms for the identification of GPCR targets, and of orthosteric and allosteric modulators
Rafael Franco, Enric I Canela, Vicent Casado & Sergi Ferre
Pages: 391-403
Published online: 29 Mar 2010
AbstractforPlatforms for the identification of GPCR targets, and of orthosteric and allosteric modulators | Full Text | References | PDF (380.6 KB)
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