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Volume 6, Issue 10

Expert Opinion on Drug Discovery

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Expert Opinion on Drug Discovery, Volume 6, Issue 10 (2011)

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Expert Opinion on Drug Discovery, Volume 6, Issue 10 (2011)

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Editorial

Computational approaches for drug target identification in pathogenic diseases

Nagasuma Chandra (Associate Professor)

Pages: 975-979

Published online: 22 Aug 2011

First Page PreviewforComputational approaches for drug target identification in pathogenic diseases | Full Text | References | PDF (305.5 KB)

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Technology Evaluation

Article

Monitoring Gq-coupled receptor response through inositol phosphate quantification with the IP-One assay

Eric Trinquet, Rochdi Bouhelal & Michel Dietz

Pages: 981-994

Published online: 08 Sep 2011

AbstractforMonitoring Gq-coupled receptor response through inositol phosphate quantification with the IP-One assay | Full Text | References | PDF (1.3 MB)

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Reviews

Article

Cannabinoid 1 G protein-coupled receptor (periphero-)neutral antagonists: emerging therapeutics for treating obesity-driven metabolic disease and reducing cardiovascular risk

David R Janero, Loren Lindsley, Venkata Kiran Vemuri & Alexandros Makriyannis

Pages: 995-1025

Published online: 02 Sep 2011

AbstractforCannabinoid 1 G protein-coupled receptor (periphero-)neutral antagonists: emerging therapeutics for treating obesity-driven metabolic disease and reducing cardiovascular risk | Full Text | References | PDF (597.9 KB)

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Article

Identifying and testing potential new anti-asthma agents

Cailong Fang, Chris J Corrigan & Sun Ying

Pages: 1027-1044

Published online: 06 Sep 2011

AbstractforIdentifying and testing potential new anti-asthma agents | Full Text | References | PDF (730.7 KB)

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Article

The design of semi-synthetic and synthetic glycoconjugate vaccines

Paolo Costantino, Rino Rappuoli & Francesco Berti

Pages: 1045-1066

Published online: 06 Sep 2011

AbstractforThe design of semi-synthetic and synthetic glycoconjugate vaccines | Full Text | References | PDF (1.8 MB)

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Article

The successes and failures of HIV drug discovery

Chie Hashimoto, Tomohiro Tanaka, Tetsuo Narumi, Wataru Nomura & Hirokazu Tamamura

Pages: 1067-1090

Published online: 02 Sep 2011

AbstractforThe successes and failures of HIV drug discovery | Full Text | References | PDF (993.5 KB)

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Article

Potential insight for drug discovery from high-fidelity receptor-mediated transduction mechanisms in insects

Robert B Raffa (Professor of Pharmacology) PhD & Kenneth F Raffa (Professor of Entomology) PhD

Pages: 1091-1101

Published online: 22 Aug 2011

AbstractforPotential insight for drug discovery from high-fidelity receptor-mediated transduction mechanisms in insects | Full Text | References | PDF (573.1 KB)

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Article

New approaches for pediatric rhabdomyosarcoma drug discovery: targeting combinatorial signaling

Venkatesh Rengaswamy, Udo Kontny & Jochen Rössler

Pages: 1103-1125

Published online: 06 Sep 2011

AbstractforNew approaches for pediatric rhabdomyosarcoma drug discovery: targeting combinatorial signaling | Full Text | References | PDF (613.1 KB)

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