Expert Opinion on Drug Discovery, Volume 8, Issue 6 (2013)

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Expert Opinion on Drug Discovery, Volume 8, Issue 6 (2013)

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Reviews

Review Article
X-ray structural information of GPCRs in drug design: what are the limitations and where do we go?
Sid Topiol
Pages: 607-620
Published online: 29 Mar 2013
AbstractforX-ray structural information of GPCRs in drug design: what are the limitations and where do we go? | Full Text | References | PDF (542 KB)
  • 578 Views
  • 15 CrossRef citations
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Review Article
Structure-based design, discovery and development of checkpoint kinase inhibitors as potential anticancer therapies
Thomas P Matthews, Alan M Jones & Ian Collins
Pages: 621-640
Published online: 18 Apr 2013
AbstractforStructure-based design, discovery and development of checkpoint kinase inhibitors as potential anticancer therapies | Full Text | References | PDF (1.4 MB)
  • 483 Views
  • 51 CrossRef citations
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Review Article
Aldehyde oxidase and its importance in novel drug discovery: present and future challenges
Enrico Garattini & Mineko Terao
Pages: 641-654
Published online: 09 Apr 2013
AbstractforAldehyde oxidase and its importance in novel drug discovery: present and future challenges | Full Text | References | PDF (873.8 KB)
  • 691 Views
  • 59 CrossRef citations
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Review Article
New advances in models and strategies for developing anti-obesity drugs
Gilbert W Kim, Jieru E Lin PharmD PhD, Erik S Blomain & Scott A Waldman MD PhD
Pages: 655-671
Published online: 29 Apr 2013
AbstractforNew advances in models and strategies for developing anti-obesity drugs | Full Text | References | PDF (375.7 KB)
  • 556 Views
  • 21 CrossRef citations
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Review Article
Recent progress on the discovery of non-peptidic direct renin inhibitors for the clinical management of hypertension
Fumiaki Yokokawa
Pages: 673-690
Published online: 18 Apr 2013
AbstractforRecent progress on the discovery of non-peptidic direct renin inhibitors for the clinical management of hypertension | Full Text | References | PDF (1.3 MB)
  • 342 Views
  • 19 CrossRef citations
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Review Article
Repairing mutated proteins – development of small molecules targeting defects in the cystic fibrosis transmembrane conductance regulator
Daniel Merk & Manfred Schubert-Zsilavecz
Pages: 691-708
Published online: 11 Apr 2013
AbstractforRepairing mutated proteins – development of small molecules targeting defects in the cystic fibrosis transmembrane conductance regulator | Full Text | References | PDF (677.2 KB)
  • 637 Views
  • 15 CrossRef citations
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Review Article
Advances in the identification of β-secretase inhibitors
Yoshio Hamada & Yoshiaki Kiso
Pages: 709-731
Published online: 09 Apr 2013
AbstractforAdvances in the identification of β-secretase inhibitors | Full Text | References | PDF (1.2 MB)
  • 432 Views
  • 26 CrossRef citations
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Review Article
New methods for the discovery and synthesis of PDE7 inhibitors as new drugs for neurological and inflammatory disorders
Maliheh Safavi, Maryam Baeeri & Mohammad Abdollahi
Pages: 733-751
Published online: 09 Apr 2013
AbstractforNew methods for the discovery and synthesis of PDE7 inhibitors as new drugs for neurological and inflammatory disorders | Full Text | References | PDF (1.3 MB)
  • 652 Views
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Research Article

Article
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Page: i
Published online: 20 May 2013
CitationforRelated articles | Full Text | PDF (209.5 KB)
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