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Volume 9, Issue 11

Expert Opinion on Drug Discovery

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Expert Opinion on Drug Discovery, Volume 9, Issue 11 (2014)

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Expert Opinion on Drug Discovery, Volume 9, Issue 11 (2014)

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Foreword

Article

Foreword

David Grech (Commissioning Editor)

Page: 1253

Published online: 22 Oct 2014

CitationforForeword | Full Text | PDF (82.3 KB)

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Editorials

Editorial

Where do we stand in the field of anti-abuse drug discovery?

Thomas M Tzschentke PhD

Pages: 1255-1258

Published online: 27 Aug 2014

AbstractforWhere do we stand in the field of anti-abuse drug discovery? | Full Text | References | PDF (137.2 KB)

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Editorial

Improving efficiency of initial tests for efficacy in smoking cessation drug discovery

Kenneth A Perkins (Professor of Psychiatry) PhD

Pages: 1259-1264

Published online: 20 Aug 2014

AbstractforImproving efficiency of initial tests for efficacy in smoking cessation drug discovery | Full Text | References | PDF (160.7 KB)

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Reviews

Review Article

Medications development for substance-use disorders: contextual influences (dis)incentivizing pharmaceutical-industry positioning

David R Janero (Professor (Adjunct Faculty), Deputy Director, Member) PhD

Pages: 1265-1279

Published online: 27 Aug 2014

AbstractforMedications development for substance-use disorders: contextual influences (dis)incentivizing pharmaceutical-industry positioning | Full Text | References | PDF (429.1 KB)

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Review Article

Appropriate experimental approaches for predicting abuse potential and addictive qualities in preclinical drug discovery

Andy N Mead DPhil

Pages: 1281-1291

Published online: 01 Sep 2014

AbstractforAppropriate experimental approaches for predicting abuse potential and addictive qualities in preclinical drug discovery | Full Text | References | PDF (248.5 KB)

277 Views
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Review Article

Designing modulators of 5-hydroxytryptamine signaling to treat abuse disorders

Sandra MW van de Wiel, Michel M Verheij & Judith R Homberg PhD

Pages: 1293-1306

Published online: 12 Sep 2014

AbstractforDesigning modulators of 5-hydroxytryptamine signaling to treat abuse disorders | Full Text | References | PDF (577.7 KB)

142 Views
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Review Article

Targeting GABA_B receptors for anti-abuse drug discovery

Tamara J Phillips (Senior Research Career Scientist, Professor and Vice Chair) PhD & Cheryl Reed (Senior Research Associate) PhD

Pages: 1307-1317

Published online: 08 Sep 2014

AbstractforTargeting GABA_B receptors for anti-abuse drug discovery | Full Text | References | PDF (357.4 KB)

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Review Article

Current approaches for the discovery of drugs that deter substance and drug abuse

Adam Yasgar & Anton Simeonov

Pages: 1319-1331

Published online: 24 Sep 2014

AbstractforCurrent approaches for the discovery of drugs that deter substance and drug abuse | Full Text | References | PDF (1.1 MB)

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Review Article

Novel approaches for the treatment of psychostimulant and opioid abuse – focus on opioid receptor-based therapies

Chris P Bailey & Stephen M Husbands

Pages: 1333-1344

Published online: 25 Sep 2014

AbstractforNovel approaches for the treatment of psychostimulant and opioid abuse – focus on opioid receptor-based therapies | Full Text | References | PDF (285.8 KB)

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Review Article

Animal models for opioid addiction drug discovery

Shaness A Grenald, Tally M Largent-Milnes & Todd W Vanderah

Pages: 1345-1354

Published online: 13 Oct 2014

AbstractforAnimal models for opioid addiction drug discovery | Full Text | References | PDF (254.4 KB)

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Drug Discovery Case Histories

Article

The development of acamprosate as a treatment against alcohol relapse

Peter R Kufahl (Research Scientist) PhD, Lucas R Watterson (Graduate Student) MS & M Foster Olive (Associate Professor) PhD

Pages: 1355-1369

Published online: 26 Sep 2014

AbstractforThe development of acamprosate as a treatment against alcohol relapse | Full Text | References | PDF (680.3 KB)

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Article

The preclinical discovery of lofexidine for the treatment of opiate addiction

Ashish P Vartak (Research Associate) BPharm PhD

Pages: 1371-1377

Published online: 26 Sep 2014

AbstractforThe preclinical discovery of lofexidine for the treatment of opiate addiction | Full Text | References | PDF (303.9 KB)

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Interview

Article

Perspectives on substance abuse drug discovery

David R Janero (Professor) PhD & David Grech

Pages: 1379-1381

Published online: 22 Oct 2014

First Page PreviewforPerspectives on substance abuse drug discovery | Full Text | PDF (114.8 KB)

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Research Articles

Article

Page: i

Published online: 22 Oct 2014

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