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Volume 16, Issue 10

Expert Opinion on Investigational Drugs

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Expert Opinion on Investigational Drugs, Volume 16, Issue 10 (2007)

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Expert Opinion on Investigational Drugs, Volume 16, Issue 10 (2007)

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Vol 33, 2024 Vol 32, 2023 Vol 31, 2022 Vol 30, 2021 Vol 29, 2020 Vol 28, 2019 Vol 27, 2018 Vol 26, 2017 Vol 25, 2016 Vol 24, 2015 Vol 23, 2014 Vol 22, 2013 Vol 21, 2012 Vol 20, 2011 Vol 19, 2010 Vol 18, 2009 Vol 17, 2008 Volume 16, 2007 Vol 15, 2006 Vol 14, 2005 Vol 13, 2004 Vol 12, 2003 Vol 11, 2002 Vol 10, 2001 Vol 9, 2000 Vol 8, 1999 Vol 7, 1998 Vol 6, 1997 Vol 5, 1996 Vol 4, 1995 Vol 3, 1994

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Editorial

Article

The withdrawal of torcetrapib from drug development: implications for the future of drugs that alter HDL metabolism

Laurence G Howes & Karam Kostner

Pages: 1509-1516

Published online: 09 Oct 2007

AbstractforThe withdrawal of torcetrapib from drug development: implications for the future of drugs that alter HDL metabolism | Full Text | References | PDF (140 KB)

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Perspective

Article

Discontinued drugs in 2006: renal, endocrine and metabolic drugs

Jerry R Colca

Pages: 1517-1523

Published online: 09 Oct 2007

AbstractforDiscontinued drugs in 2006: renal, endocrine and metabolic drugs | Full Text | References | PDF (125.2 KB)

74 Views
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Review

Article

Next-generation calcineurin inhibitors for ophthalmic indications

Eddy Anglade MD, Randall Yatscoff PhD, Robert Foster PhD & Ulrich Grau PhD

Pages: 1525-1540

Published online: 09 Oct 2007

AbstractforNext-generation calcineurin inhibitors for ophthalmic indications | Full Text | References | PDF (681.8 KB)

315 Views
27 CrossRef citations
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Article

Novel cardiac myosin activators for acute heart failure

Thanjavur KM Bragadeesh MD, Gaurav Mathur MD, Andrew L Clark MD & John GF Cleland MD

Pages: 1541-1548

Published online: 09 Oct 2007

AbstractforNovel cardiac myosin activators for acute heart failure | Full Text | References | PDF (201.9 KB)

110 Views
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Article

Future options for imatinib mesilate-resistant tumors

Kamalesh K Sankhala & Kyriakos P Papadopoulos MD

Pages: 1549-1560

Published online: 09 Oct 2007

AbstractforFuture options for imatinib mesilate-resistant tumors | Full Text | References | PDF (169.6 KB)

90 Views
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Article

Peroxisome proliferator-activated receptor-γ ligands as investigational modulators of angiogenesis

Costas Giaginis, Alexandra Margeli & Stamatios Theocharis MD

Pages: 1561-1572

Published online: 09 Oct 2007

AbstractforPeroxisome proliferator-activated receptor-γ ligands as investigational modulators of angiogenesis | Full Text | References | PDF (153.3 KB)

112 Views
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Article

The therapeutic potential of O⁶-alkylguanine DNA alkyltransferase inhibitors

Omar Khan MD BSc (Hons) MBBS MRCP (UK) & Mark R Middleton MD BA BM BCh MRCP (UK) PhD

Pages: 1573-1584

Published online: 09 Oct 2007

AbstractforThe therapeutic potential of O⁶-alkylguanine DNA alkyltransferase inhibitors | Full Text | References | PDF (207.8 KB)

111 Views
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Article

Small-molecule inhibitors of PDE-IV and -VII in the treatment of respiratory diseases and chronic inflammation

Lalitha Vijayakrishnan, Sonali Rudra, Mathew S Eapen, Sunanda Dastidar & Abhijit Ray

Pages: 1585-1599

Published online: 09 Oct 2007

AbstractforSmall-molecule inhibitors of PDE-IV and -VII in the treatment of respiratory diseases and chronic inflammation | Full Text | References | PDF (312 KB)

165 Views
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Article

The anti-inflammatory effect of A₃ adenosine receptor agonists: a novel targeted therapy for rheumatoid arthritis

Sara Bar-Yehuda PhD of Biology, Head Research Laboratories, Michael H Silverman MD Medical Director, William D Kerns MDV, VP of Drug Development, Avivit Ochaion, Shira Cohen & Pnina Fishman

Pages: 1601-1613

Published online: 09 Oct 2007

AbstractforThe anti-inflammatory effect of A₃ adenosine receptor agonists: a novel targeted therapy for rheumatoid arthritis | Full Text | References | PDF (611.9 KB)

347 Views
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Drug Evaluation

Article

Oxcarbazepine in neuropathic pain

Wassim Nasreddine MD & Ahmad Beydoun MD

Pages: 1615-1625

Published online: 09 Oct 2007

AbstractforOxcarbazepine in neuropathic pain | Full Text | References | PDF (188.1 KB)

278 Views
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Article

Omega-3 fatty acid eicosapentaenoic acid. A new treatment for psychiatric and neurodegenerative diseases: a review of clinical investigations

Cai Song MD PhD & Shannon Zhao

Pages: 1627-1638

Published online: 09 Oct 2007

AbstractforOmega-3 fatty acid eicosapentaenoic acid. A new treatment for psychiatric and neurodegenerative diseases: a review of clinical investigations | Full Text | References | PDF (162.6 KB)

282 Views
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Article

V₂ receptor antagonism with tolvaptan in heart failure

Lisa C Costello-Boerrigter MD PhD, Guido Boerrigter MD & John C Burnett Jr MD

Pages: 1639-1647

Published online: 09 Oct 2007

AbstractforV₂ receptor antagonism with tolvaptan in heart failure | Full Text | References | PDF (186.1 KB)

116 Views
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Article

C.E.R.A.: pharmacodynamics, pharmacokinetics and efficacy in patients with chronic kidney disease

Francesco Locatelli & Bruno Reigner

Pages: 1649-1661

Published online: 09 Oct 2007

AbstractforC.E.R.A.: pharmacodynamics, pharmacokinetics and efficacy in patients with chronic kidney disease | Full Text | References | PDF (203.5 KB)

493 Views
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Article

Bazedoxifene and bazedoxifene combined with conjugated estrogens for the management of postmenopausal osteoporosis

E Michael Lewiecki

Pages: 1663-1672

Published online: 09 Oct 2007

AbstractforBazedoxifene and bazedoxifene combined with conjugated estrogens for the management of postmenopausal osteoporosis | Full Text | References | PDF (146.8 KB)

256 Views
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Article

Inhaled insulin using AERx^® insulin Diabetes Management System (AERx^® iDMS)

Sunder Mudaliar MD

Pages: 1673-1681

Published online: 09 Oct 2007

AbstractforInhaled insulin using AERx^® insulin Diabetes Management System (AERx^® iDMS) | Full Text | References | PDF (157.4 KB)

121 Views
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Article

Pixantrone: a novel aza-anthracenedione in the treatment of non-Hodgkin's lymphomas

Loaie M El-Helw MD & Barry W Hancock MD

Pages: 1683-1691

Published online: 09 Oct 2007

AbstractforPixantrone: a novel aza-anthracenedione in the treatment of non-Hodgkin's lymphomas | Full Text | References | PDF (158.6 KB)

137 Views
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Article

The therapeutic role of targeting protein kinase C in solid and hematologic malignancies

Klaus Podar MD PhD, Marc S Raab MD, Dharminder Chauhan PhD & Kenneth C Anderson MD

Pages: 1693-1707

Published online: 09 Oct 2007

AbstractforThe therapeutic role of targeting protein kinase C in solid and hematologic malignancies | Full Text | References | PDF (205.3 KB)

219 Views
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Article

Oral beclomethasone dipropionate: a topically active corticosteroid for the treatment of gastrointestinal graft-versus-host disease following allogeneic hematopoietic cell transplantation

George B McDonald MD

Pages: 1709-1724

Published online: 09 Oct 2007

AbstractforOral beclomethasone dipropionate: a topically active corticosteroid for the treatment of gastrointestinal graft-versus-host disease following allogeneic hematopoietic cell transplantation | Full Text | References | PDF (344.6 KB)

339 Views
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Meeting Highlights

Article

14th Annual Meeting of the Psychoneuroimmunology Research Society

28 – 29 May 2007, Bordeaux, France

Martin Braddock

Pages: 1725-1734

Published online: 09 Oct 2007

Abstractfor14th Annual Meeting of the Psychoneuroimmunology Research Society | Full Text | References | PDF (137.1 KB)

38 Views
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Article

67th Annual Meeting of the American Diabetes Association

Jerry R Colca

Pages: 1735-1739

Published online: 09 Oct 2007

Abstractfor67th Annual Meeting of the American Diabetes Association | Full Text | References | PDF (105.6 KB)

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