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Volume 18, Issue 9

Expert Opinion on Investigational Drugs

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Expert Opinion on Investigational Drugs, Volume 18, Issue 9 (2009)

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Expert Opinion on Investigational Drugs, Volume 18, Issue 9 (2009)

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Discontinued Drugs Perspective

Article

Discontinued drugs in 2008: endocrine and metabolic

Jerry R Colca

Pages: 1243-1255

Published online: 14 Aug 2009

AbstractforDiscontinued drugs in 2008: endocrine and metabolic | Full Text | References | PDF (339.8 KB)

142 Views
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Reviews

Article

Is there a palliative benefit of gemcitabine plus fluoropyrimidines in patients with refractory colorectal cancer? A review of the literature

Previously presented: Poster at the 2008 Gastrointestinal Cancer Symposium (Abstract No. 512)

MY Merl, CJ Hoimes, T Pham & M Wasif Saif

Pages: 1257-1264

Published online: 11 Jul 2009

AbstractforIs there a palliative benefit of gemcitabine plus fluoropyrimidines in patients with refractory colorectal cancer? A review of the literature | Full Text | References | PDF (234.8 KB)

185 Views
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Article

Novel inhibitors of the PI3K family

Amancio Carnero

Pages: 1265-1277

Published online: 10 Jul 2009

AbstractforNovel inhibitors of the PI3K family | Full Text | References | PDF (350.7 KB)

508 Views
29 CrossRef citations
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Article

New generation azole antifungals in clinical investigation

Corrado Girmenia

Pages: 1279-1295

Published online: 14 Aug 2009

AbstractforNew generation azole antifungals in clinical investigation | Full Text | References | PDF (333.6 KB)

701 Views
78 CrossRef citations
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Article

Somatostatin and somatostatin receptors: implications for neoplastic growth and cancer biology

Pavlos Msaouel MD, Evanthia Galanis MD & Michael Koutsilieris MD PhD

Pages: 1297-1316

Published online: 14 Aug 2009

AbstractforSomatostatin and somatostatin receptors: implications for neoplastic growth and cancer biology | Full Text | References | PDF (558.3 KB)

282 Views
24 CrossRef citations
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Article

Platelet P2Y12 receptor inhibition by thienopyridines: status and future

Italo Porto MD PhD, Simona Giubilato, Giovanni Luigi De Maria, Luigi Marzio Biasucci & Filippo Crea

Pages: 1317-1332

Published online: 14 Aug 2009

AbstractforPlatelet P2Y12 receptor inhibition by thienopyridines: status and future | Full Text | References | PDF (410.8 KB)

325 Views
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Article

Targeting the PI3K/AKT/mTOR signaling network in acute myelogenous leukemia

Alberto M Martelli MD PhD, Camilla Evangelisti PhD, Francesca Chiarini BSc, Cecilia Grimaldi BSc, Lucia Manzoli MD PhD & James A McCubrey PhD

Pages: 1333-1349

Published online: 14 Aug 2009

AbstractforTargeting the PI3K/AKT/mTOR signaling network in acute myelogenous leukemia | Full Text | References | PDF (392.5 KB)

683 Views
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Article

Novel targets in esophageal and gastric cancer: beyond antiangiogenesis

Wooin Lee, Jignesh H Patel & A Craig Lockhart

Pages: 1351-1364

Published online: 30 Jul 2009

AbstractforNovel targets in esophageal and gastric cancer: beyond antiangiogenesis | Full Text | References | PDF (381 KB)

202 Views
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Drug Evaluations

Article

Rosiglitazone maleate + metformin hydrochloride extend: review of an emerging compound

Alice YY Cheng MD FRCPC & Robert G Josse BSc MBBS FRCP FRCPC FACP FACE

Pages: 1365-1373

Published online: 30 Jul 2009

AbstractforRosiglitazone maleate + metformin hydrochloride extend: review of an emerging compound | Full Text | References | PDF (275 KB)

71 Views
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Article

Retaspimycin hydrochloride (IPI-504): a novel heat shock protein inhibitor as an anticancer agent

Britt Erika Hanson DO & David H Vesole MD PhD

Pages: 1375-1383

Published online: 30 Jul 2009

AbstractforRetaspimycin hydrochloride (IPI-504): a novel heat shock protein inhibitor as an anticancer agent | Full Text | References | PDF (299.4 KB)

301 Views
39 CrossRef citations
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Article

A fixed dose combination of ibuprofen and famotidine

John W Birk & Matthew Myers

Pages: 1385-1391

Published online: 06 Aug 2009

AbstractforA fixed dose combination of ibuprofen and famotidine | Full Text | References | PDF (228.4 KB)

161 Views
4 CrossRef citations
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Article

Anidulafungin and voriconazole in invasive fungal disease: pharmacological data and their use in combination

Susanne Perkhofer & Cornelia Lass-Flörl

Pages: 1393-1404

Published online: 05 Aug 2009

AbstractforAnidulafungin and voriconazole in invasive fungal disease: pharmacological data and their use in combination | Full Text | References | PDF (342.3 KB)

252 Views
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Article

Taspoglutide: a long acting human glucagon-like polypeptide-1 analogue

Kjetil Retterstøl

Pages: 1405-1411

Published online: 14 Aug 2009

AbstractforTaspoglutide: a long acting human glucagon-like polypeptide-1 analogue | Full Text | References | PDF (247.5 KB)

258 Views
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Article

Corticorelin acetate injections for the treatment of peritumoral brain edema

Jennifer A Moliterno MD, Euphael Henry MD & Susan C Pannullo MD

Pages: 1413-1419

Published online: 14 Aug 2009

AbstractforCorticorelin acetate injections for the treatment of peritumoral brain edema | Full Text | References | PDF (220.6 KB)

119 Views
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Key Paper Evaluation

Article

Golimumab for severe asthma

Evaluation: Wenzel SE, Barnes PJ, Bleecker ER et al. A randomized, double-blind, placebo-controlled study of tumor necrosis factor-alpha blockade in severe persistent asthma. Am J Respir Crit Care Med 2009;179(7):549-58

Sabina A Antoniu MD PhD

Pages: 1421-1423

Published online: 14 Aug 2009

AbstractforGolimumab for severe asthma | Full Text | References | PDF (178.1 KB)

128 Views
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