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Volume 19, Issue 10

Expert Opinion on Investigational Drugs

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Expert Opinion on Investigational Drugs, Volume 19, Issue 10 (2010)

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Expert Opinion on Investigational Drugs, Volume 19, Issue 10 (2010)

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Original Research

Article

No clinically relevant drug–drug interactions when dalcetrapib is co-administered with atorvastatin

Michael Derks, Markus Abt, Graeme Parr, Georgina Meneses-Lorente, Anne-Marie Young & Mary Phelan

Pages: 1135-1145

Published online: 26 Aug 2010

AbstractforNo clinically relevant drug–drug interactions when dalcetrapib is co-administered with atorvastatin | Full Text | References | PDF (329.2 KB) | Supplemental

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Reviews

Article

Investigational agents for Crohn's disease

Mario Cottone, Ambrogio Orlando & Sara Renna

Pages: 1147-1159

Published online: 12 Aug 2010

AbstractforInvestigational agents for Crohn's disease | Full Text | References | PDF (337.5 KB)

330 Views
10 CrossRef citations
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Article

Investigational agents for the irritable bowel syndrome

Ola Ghaith MD, Mustapha El-Halabi MD, Jana G Hashash MD & Ala I Sharara MD FACG AGAF

Pages: 1161-1178

Published online: 13 Sep 2010

AbstractforInvestigational agents for the irritable bowel syndrome | Full Text | References | PDF (321.1 KB)

238 Views
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Article

Erythropoietin molecules to treat acute ischemic stroke: a translational dilemma!

Paul A Lapchak PhD FAHA

Pages: 1179-1186

Published online: 09 Sep 2010

AbstractforErythropoietin molecules to treat acute ischemic stroke: a translational dilemma! | Full Text | References | PDF (202.3 KB)

125 Views
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Article

Quetiapine: novel uses in the treatment of depressive and anxiety disorders

Arun V Ravindran, Abdullah Al-Subaie & Gebrehiwot Abraham

Pages: 1187-1204

Published online: 27 Aug 2010

AbstractforQuetiapine: novel uses in the treatment of depressive and anxiety disorders | Full Text | References | PDF (259.7 KB)

636 Views
16 CrossRef citations
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Article

Molecular targeted therapy for patients with melanoma: the promise of MAPK pathway inhibition and beyond

Ryan J Sullivan & Michael B Atkins

Pages: 1205-1216

Published online: 05 Aug 2010

AbstractforMolecular targeted therapy for patients with melanoma: the promise of MAPK pathway inhibition and beyond | Full Text | References | PDF (278.4 KB)

150 Views
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Article

The inhibitory GABA system as a therapeutic target for cognitive symptoms in schizophrenia: investigational agents in the pipeline

Christiaan H Vinkers, Naheed R Mirza, Berend Olivier & René S Kahn

Pages: 1217-1233

Published online: 03 Sep 2010

AbstractforThe inhibitory GABA system as a therapeutic target for cognitive symptoms in schizophrenia: investigational agents in the pipeline | Full Text | References | PDF (472.8 KB)

590 Views
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Drug Evaluations

Article

The long and winding road for the development of tasquinimod as an oral second-generation quinoline-3-carboxamide antiangiogenic drug for the treatment of prostate cancer

John T Isaacs

Pages: 1235-1243

Published online: 13 Sep 2010

AbstractforThe long and winding road for the development of tasquinimod as an oral second-generation quinoline-3-carboxamide antiangiogenic drug for the treatment of prostate cancer | Full Text | References | PDF (358 KB)

347 Views
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Article

Varespladib methyl in cardiovascular disease

Robert S Rosenson MD, Heather Fraser PhD, Joaquim Trias PhD & Colin Hislop MD

Pages: 1245-1255

Published online: 01 Sep 2010

AbstractforVarespladib methyl in cardiovascular disease | Full Text | References | PDF (270.6 KB)

263 Views
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Article

Asimadoline in the treatment of irritable bowel syndrome

Allen W Mangel MD PhD & Valerie SL Williams

Pages: 1257-1264

Published online: 01 Sep 2010

AbstractforAsimadoline in the treatment of irritable bowel syndrome | Full Text | References | PDF (321.5 KB)

217 Views
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Article

Aliskiren: beyond blood pressure reduction

Graziano Riccioni MD PhD, Nicola Vitulano MD, Alessandra Zanasi MD, Fulvio Bellocci & Nicolantonio d'Orazio

Pages: 1265-1274

Published online: 03 Sep 2010

AbstractforAliskiren: beyond blood pressure reduction | Full Text | References | PDF (294.7 KB)

163 Views
7 CrossRef citations
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Article

High-dose treosulfan in conditioning prior to hematopoietic stem cell transplantation

Franciszek K Główka, Michał Romański MSc & Jacek Wachowiak

Pages: 1275-1295

Published online: 13 Sep 2010

AbstractforHigh-dose treosulfan in conditioning prior to hematopoietic stem cell transplantation | Full Text | References | PDF (430.1 KB)

328 Views
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Article

Berberine: a potential phytochemical with multispectrum therapeutic activities

Parameswara Rao Vuddanda, Subhashis Chakraborty & Sanjay Singh

Pages: 1297-1307

Published online: 13 Sep 2010

AbstractforBerberine: a potential phytochemical with multispectrum therapeutic activities | Full Text | References | PDF (264 KB)

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