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Volume 22, Issue 6

Expert Opinion on Investigational Drugs

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Expert Opinion on Investigational Drugs, Volume 22, Issue 6 (2013)

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Expert Opinion on Investigational Drugs, Volume 22, Issue 6 (2013)

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Editorial

Protein kinase inhibitors: breakthrough medicines and the next generation

Tomi K Sawyer, Joe C Wu, Jonathon R Sawyer & Jessie M English

Pages: 675-678

Published online: 25 May 2013

AbstractforProtein kinase inhibitors: breakthrough medicines and the next generation | Full Text | References | PDF (220.4 KB)

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Editorial

Overcoming resistance to mTOR inhibition for enhanced strategies in clinical trials

Aung Naing MD FACP

Pages: 679-685

Published online: 30 Apr 2013

First Page PreviewforOvercoming resistance to mTOR inhibition for enhanced strategies in clinical trials | Full Text | References | PDF (336.9 KB)

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Reviews

Review Article

Investigational Janus kinase inhibitors

Constantine S Tam MBBS MD & Srdan Verstovsek MD PhD

Pages: 687-699

Published online: 23 Feb 2013

AbstractforInvestigational Janus kinase inhibitors | Full Text | References | PDF (492.6 KB)

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Article

Therapeutic potential of serum and glucocorticoid inducible kinase inhibition

Florian Lang & Jakob Voelkl

Pages: 701-714

Published online: 19 Mar 2013

AbstractforTherapeutic potential of serum and glucocorticoid inducible kinase inhibition | Full Text | References | PDF (559 KB)

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Review Article

Next generation of mammalian target of rapamycin inhibitors for the treatment of cancer

Valerie Nelson, Jessica K Altman & Leonidas C Platanias

Pages: 715-722

Published online: 02 Apr 2013

AbstractforNext generation of mammalian target of rapamycin inhibitors for the treatment of cancer | Full Text | References | PDF (316.5 KB)

378 Views
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Review Article

Cyclin-dependent kinase inhibitor therapy for hematologic malignancies

Prithviraj Bose, Gary L Simmons & Steven Grant

Pages: 723-738

Published online: 06 May 2013

AbstractforCyclin-dependent kinase inhibitor therapy for hematologic malignancies | Full Text | References | PDF (387.2 KB)

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Review Article

Phase I/II RAF kinase inhibitors in cancer therapy

Samra Turajlic, Zohra Ali, Nadia Yousaf & James Larkin

Pages: 739-749

Published online: 06 May 2013

AbstractforPhase I/II RAF kinase inhibitors in cancer therapy | Full Text | References | PDF (346.6 KB)

439 Views
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Review Article

Tyrosine kinase inhibitors as novel drugs for the treatment of diabetes

Patricia O Prada & Mario JA Saad

Pages: 751-763

Published online: 25 May 2013

AbstractforTyrosine kinase inhibitors as novel drugs for the treatment of diabetes | Full Text | References | PDF (676.9 KB)

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Drug Evaluations

Article

Axitinib for the treatment of advanced non-small-cell lung cancer

Judy W King MRCP PhD & Siow-Ming Lee FRCP PhD

Pages: 765-773

Published online: 01 Mar 2013

Abstractfor Axitinib for the treatment of advanced non-small-cell lung cancer | Full Text | References | PDF (255.1 KB)

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Article

Targeting the JAK-STAT pathway in lymphoma: a focus on pacritinib

Enrico Derenzini MD & Anas Younes MD

Pages: 775-785

Published online: 26 Feb 2013

AbstractforTargeting the JAK-STAT pathway in lymphoma: a focus on pacritinib | Full Text | References | PDF (611.3 KB)

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Review Article

Imatinib and prostate cancer: lessons learned from targeting the platelet-derived growth factor receptor

Aaron Rosenberg MD & Paul Mathew MD

Pages: 787-794

Published online: 01 Apr 2013

Abstractfor Imatinib and prostate cancer: lessons learned from targeting the platelet-derived growth factor receptor | Full Text | References | PDF (309.2 KB)

461 Views
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Review Article

Dasatinib: a novel therapy for breast cancer?

Kevin S Scher MD MBA & George Somlo MD

Pages: 795-801

Published online: 18 Apr 2013

Abstractfor Dasatinib: a novel therapy for breast cancer? | Full Text | References | PDF (226.4 KB)

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Research Article

Article

Page: i

Published online: 25 May 2013

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