Expert Opinion on Investigational Drugs, Volume 30, Issue 12 (2021)

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Expert Opinion on Investigational Drugs, Volume 30, Issue 12 (2021)

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Drug Evaluation

Article
Ritlecitinib: an investigational drug for the treatment of moderate to severe alopecia areata
Samantha Eisman & Rodney Sinclair
Pages: 1169-1174
Published online: 20 Dec 2021
AbstractforRitlecitinib: an investigational drug for the treatment of moderate to severe alopecia areata | Full Text | References | PDF (369.6 KB) | EPUB | Supplemental
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Perspective

Article
What have we learned from past failures of investigational drugs for Alzheimer’s disease?
Bruno P. Imbimbo & Mark Watling
Pages: 1175-1182
Published online: 20 Dec 2021
AbstractforWhat have we learned from past failures of investigational drugs for Alzheimer’s disease? | Full Text | References | PDF (299 KB) | EPUB
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Review

COVID-related fibrosis: insights into potential drug targets
Giacomo Sgalla, Alessia Comes, Marialessia Lerede & Luca Richeldi
Pages: 1183-1195
Published online: 01 Dec 2021
AbstractforCOVID-related fibrosis: insights into potential drug targets | Full Text | References | PDF (364.5 KB) | EPUB
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Carbonic anhydrase inhibitors: an update on experimental agents for the treatment and imaging of hypoxic tumors
Claudiu T. Supuran
Pages: 1197-1208
Published online: 13 Dec 2021
AbstractforCarbonic anhydrase inhibitors: an update on experimental agents for the treatment and imaging of hypoxic tumors | Full Text | References | PDF (581 KB) | EPUB
  • 375 Views
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Investigational therapies targeting CD3 for prevention and treatment of type 1 diabetes
Carmen Mignogna, Ernesto Maddaloni, Luca D’Onofrio & Raffaella Buzzetti
Pages: 1209-1219
Published online: 10 Jan 2022
AbstractforInvestigational therapies targeting CD3 for prevention and treatment of type 1 diabetes | Full Text | References | PDF (1.3 MB) | EPUB
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Combination therapies in clinical trials for renal cell carcinoma: how could they impact future treatments?
Will Ince & Tim Eisen
Pages: 1221-1229
Published online: 04 Jan 2022
AbstractforCombination therapies in clinical trials for renal cell carcinoma: how could they impact future treatments? | Full Text | References | PDF (1.5 MB) | EPUB
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Original Research

Article
Quantitative evaluation of drug efficacy in the treatment of myasthenia gravis
Rui Chen, Ningyuan Zhang, Lili Gao, Ying Zhong, Ling Xu, Hongxia Liu, Qingshan Zheng & Lujin Li
Pages: 1231-1240
Published online: 06 Dec 2021
AbstractforQuantitative evaluation of drug efficacy in the treatment of myasthenia gravis | Full Text | References | PDF (3.6 MB) | EPUB | Supplemental
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Article
Safety, tolerability, pharmacodynamics, and pharmacokinetics of CJC-1134-PC in healthy Chinese subjects and type-2 diabetic subjects
Yanhua Ding, Hong Zhang, Xiaoxue Zhu, Min Wu, Lizhi Yang, Zhiwen Yao, Qiang Xie, Xiping Liu & Cuiyun Li
Pages: 1241-1248
Published online: 29 Nov 2021
AbstractforSafety, tolerability, pharmacodynamics, and pharmacokinetics of CJC-1134-PC in healthy Chinese subjects and type-2 diabetic subjects | Full Text | References | PDF (536.8 KB) | EPUB
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