Expert Opinion on Investigational Drugs, Volume 31, Issue 8 (2022)

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Expert Opinion on Investigational Drugs, Volume 31, Issue 8 (2022)

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Drug Evaluation

Article
ALZT-OP1: an experimental combination regimen for the treatment of Alzheimer’s disease
Madia Lozupone, Giuseppe Berardino, Anita Mollica, Rodolfo Sardone, Vittorio Dibello, Roberta Zupo, Luisa Lampignano, Fabio Castellana, Ilaria Bortone, Roberta Stallone, Antonio Daniele, Mario Altamura, Antonello Bellomo, Vincenzo Solfrizzi & Francesco Panza
Pages: 759-771
Published online: 29 Jun 2022
AbstractforALZT-OP1: an experimental combination regimen for the treatment of Alzheimer’s disease | Full Text | References | PDF (1.5 MB) | EPUB
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Article
AXS-05: an investigational treatment for Alzheimer’s disease-associated agitation
Kristen Ward & Leslie Citrome
Pages: 773-780
Published online: 06 Jul 2022
AbstractforAXS-05: an investigational treatment for Alzheimer’s disease-associated agitation | Full Text | References | PDF (366.1 KB) | EPUB
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Review

Innate immunity as a target for novel therapeutics in triple negative breast cancer
Theo Borgovan, Niranjan Yanamandra & Hank Schmidt
Pages: 781-794
Published online: 12 Jul 2022
AbstractforInnate immunity as a target for novel therapeutics in triple negative breast cancer | Full Text | References | PDF (1 MB) | EPUB
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Invasive candidiasis: investigational drugs in the clinical development pipeline and mechanisms of action
Martin Hoenigl, Rosanne Sprute, Amir Arastehfar, John R. Perfect, Cornelia Lass-Flörl, Romuald Bellmann, Juergen Prattes, George R. Thompson III, Nathan P. Wiederhold, Mohanad M. Al Obaidi, Birgit Willinger, Maiken C. Arendrup, Philipp Koehler, Matteo Oliverio, Matthias Egger, Ilan S. Schwartz, Oliver A. Cornely, Peter G. Pappas & Robert Krause
Pages: 795-812
Published online: 15 Jun 2022
AbstractforInvasive candidiasis: investigational drugs in the clinical development pipeline and mechanisms of action | Full Text | References | PDF (1.9 MB) | EPUB
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Perspective

Article
Investigational therapeutics for the treatment of progressive supranuclear palsy
David G Coughlin & Irene Litvan
Pages: 813-823
Published online: 13 Jun 2022
AbstractforInvestigational therapeutics for the treatment of progressive supranuclear palsy | Full Text | References | PDF (2.3 MB) | EPUB
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Review

Investigational drugs in early clinical development for portal hypertension
Susana G. Rodrigues, Yuly P. Mendoza & Jaime Bosch
Pages: 825-842
Published online: 05 Jul 2022
AbstractforInvestigational drugs in early clinical development for portal hypertension | Full Text | References | PDF (2.1 MB) | EPUB
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Current emerging and investigational drugs for the treatment of chronic hand eczema
Julia Cheng, Paola Facheris, Benjamin Ungar & Emma Guttman-Yassky
Pages: 843-853
Published online: 17 Jun 2022
AbstractforCurrent emerging and investigational drugs for the treatment of chronic hand eczema | Full Text | References | PDF (362.1 KB) | EPUB
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Perspective

Article
Immunotherapy for triple negative breast cancer: How can pathologic responses to experimental drugs in early-stage disease be enhanced?
Federica Giugliano, Carmine Valenza, Paolo Tarantino & Giuseppe Curigliano
Pages: 855-874
Published online: 06 Jul 2022
AbstractforImmunotherapy for triple negative breast cancer: How can pathologic responses to experimental drugs in early-stage disease be enhanced? | Full Text | References | PDF (4.6 MB) | EPUB
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