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Volume 32, Issue 11

Expert Opinion on Investigational Drugs

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Expert Opinion on Investigational Drugs, Volume 32, Issue 11 (2023)

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Expert Opinion on Investigational Drugs, Volume 32, Issue 11 (2023)

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Vol 33, 2024 Volume 32, 2023 Vol 31, 2022 Vol 30, 2021 Vol 29, 2020 Vol 28, 2019 Vol 27, 2018 Vol 26, 2017 Vol 25, 2016 Vol 24, 2015 Vol 23, 2014 Vol 22, 2013 Vol 21, 2012 Vol 20, 2011 Vol 19, 2010 Vol 18, 2009 Vol 17, 2008 Vol 16, 2007 Vol 15, 2006 Vol 14, 2005 Vol 13, 2004 Vol 12, 2003 Vol 11, 2002 Vol 10, 2001 Vol 9, 2000 Vol 8, 1999 Vol 7, 1998 Vol 6, 1997 Vol 5, 1996 Vol 4, 1995 Vol 3, 1994

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Editorial

Experimental drugs for Friedrich’s ataxia: progress and setbacks in clinical trials

Sylvia Boesch & Elisabetta Indelicato

Pages: 967-969

Published online: 24 Nov 2023

First Page PreviewforExperimental drugs for Friedrich’s ataxia: progress and setbacks in clinical trials | Full Text | References | PDF (164.4 KB) | EPUB

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Free Access

Drug Evaluation

Review Article

Bepirovirsen (GSK3228836) in chronic hepatitis B infection: an evaluation of phase II progress

Lung-Yi Mak, Rex Wan-Hin Hui, James Fung, Wai-Kay Seto & Man-Fung Yuen

Pages: 971-983

Published online: 24 Nov 2023

AbstractforBepirovirsen (GSK3228836) in chronic hepatitis B infection: an evaluation of phase II progress | Full Text | References | PDF (5.5 MB) | EPUB

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Review Article

Evaluating phase II results of Baxdrostat, an aldosterone synthase inhibitor for hypertension

Ayoola Awosika, Yoonje Cho, Ujjal Bose, Adekunle E. Omole & Uzochukwu Adabanya

Pages: 985-995

Published online: 24 Nov 2023

AbstractforEvaluating phase II results of Baxdrostat, an aldosterone synthase inhibitor for hypertension | Full Text | References | PDF (2 MB) | EPUB

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Key Paper Evaluation

Review Article

Retatrutide showing promise in obesity (and type 2 diabetes)

Sheila A Doggrell

Pages: 997-1001

Published online: 24 Nov 2023

AbstractforRetatrutide showing promise in obesity (and type 2 diabetes) | Full Text | References | PDF (190.8 KB) | EPUB

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Special Report

Report

Retatrutide: a triple incretin receptor agonist for obesity management

Avik Ray

Pages: 1003-1008

Published online: 24 Nov 2023

AbstractforRetatrutide: a triple incretin receptor agonist for obesity management | Full Text | References | PDF (550.2 KB) | EPUB

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Review

Review Article

Investigational drugs inhibiting complement for the treatment of geographic atrophy

Lorenzo Ferro Desideri, Dmitri Artemiev, Enrico Bernardi, Karin Paschon, Souska Zandi, Martin Zinkernagel & Rodrigo Anguita

Pages: 1009-1016

Published online: 24 Nov 2023

AbstractforInvestigational drugs inhibiting complement for the treatment of geographic atrophy | Full Text | References | PDF (682.7 KB) | EPUB

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Review Article

Prostaglandin FP receptor agonists in the treatment of glaucoma and ocular hypertension: a literature review

Sophia Moshegov & Nathan Mitchell Kerr

Pages: 1017-1023

Published online: 24 Nov 2023

AbstractforProstaglandin FP receptor agonists in the treatment of glaucoma and ocular hypertension: a literature review | Full Text | References | PDF (241 KB) | EPUB

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Review Article

Emerging pharmacotherapies for the treatment of pulmonary arterial hypertension

Roger Auth & James R. Klinger

Pages: 1025-1042

Published online: 24 Nov 2023

AbstractforEmerging pharmacotherapies for the treatment of pulmonary arterial hypertension | Full Text | References | PDF (2.9 MB) | EPUB

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Review Article

Inhibition of KIT for chronic urticaria: a status update on drugs in early clinical development

Bettina Wedi

Pages: 1043-1054

Published online: 24 Nov 2023

AbstractforInhibition of KIT for chronic urticaria: a status update on drugs in early clinical development | Full Text | References | PDF (708.9 KB) | EPUB

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Review Article

Hepatic encephalopathy: investigational drugs in preclinical and early phase development

Tiziano Balzano, Marta Llansola, Yaiza M. Arenas, Paula Izquierdo-Altarejos & Vicente Felipo

Pages: 1055-1069

Published online: 24 Nov 2023

AbstractforHepatic encephalopathy: investigational drugs in preclinical and early phase development | Full Text | References | PDF (1.7 MB) | EPUB

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Review Article

Developments and challenges for new and emergent preparations for male hypogonadism treatment

Giovanni Corona, Clotilde Sparano, Giulia Rastrelli, Linda Vignozzi & Mario Maggi

Pages: 1071-1084

Published online: 24 Nov 2023

AbstractforDevelopments and challenges for new and emergent preparations for male hypogonadism treatment | Full Text | References | PDF (1.8 MB) | EPUB

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Original Research

Article

First-in-human trial of SAR107375E, a novel small molecule anticoagulant with dual inhibition of factor Xa and factor IIa

Shuanzhi Wu, Tenghua Wang, Jieyun Li, Zhixin Zhang, Chen Li, Shuangshuang Xiao, Jin He, Xuan Wang, Zhiqin Hu, Xiaole Wang, Sichao Zheng, Xintong Liang, Guiying Chen, Yongmei Li, Xianbo Li, Yaoxuan Zhan, Qinwen Zou, Hongliang Jiang, Qingshan Zheng, Li Ban, Haiyan Liu & Yi Fang

Pages: 1085-1094

Published online: 24 Nov 2023

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