Expert Opinion on Investigational Drugs, Volume 33, Issue 3 (2024)

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Expert Opinion on Investigational Drugs, Volume 33, Issue 3 (2024)

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Special Report

Report
KIT/PDGFRA inhibitors for the treatment of gastrointestinal stromal tumors: getting to the gist of the problem
Carlo María Cicala, Iván Olivares-Rivas, Jon Ander Aguirre-Carrillo & César Serrano
Pages: 159-170
Published online: 14 Feb 2024
AbstractforKIT/PDGFRA inhibitors for the treatment of gastrointestinal stromal tumors: getting to the gist of the problem | Full Text | References | PDF (1.4 MB) | EPUB
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Report
Deterministic reprogramming and signaling activation following targeted therapy in non-small cell lung cancer driven by mutations or oncogenic fusions
Rafael Rosell, Carlos Pedraz-Valdunciel, Anisha Jain, Chandan Shivamallu & Andrés Aguilar
Pages: 171-182
Published online: 23 Feb 2024
AbstractforDeterministic reprogramming and signaling activation following targeted therapy in non-small cell lung cancer driven by mutations or oncogenic fusions | Full Text | References | PDF (5.7 MB) | EPUB
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Perspective

Comment
GPR119 agonists for type 2 diabetes: past failures and future hopes for preclinical and early phase candidates
Deanne H Hryciw, Rhiannon K Patten, Raymond J Rodgers, Joseph Proietto, Dana S Hutchinson & Andrew J McAinch
Pages: 183-190
Published online: 23 Feb 2024
AbstractforGPR119 agonists for type 2 diabetes: past failures and future hopes for preclinical and early phase candidates | Full Text | References | PDF (279.9 KB) | EPUB
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Review

Review Article
Kallikrein inhibitors for angioedema: the progress of preclinical and early phase studies
Henriette Farkas & Zsuzsanna Balla
Pages: 191-200
Published online: 26 Feb 2024
AbstractforKallikrein inhibitors for angioedema: the progress of preclinical and early phase studies | Full Text | References | PDF (829.7 KB) | EPUB
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Review Article
Duchenne muscular dystrophy: promising early-stage clinical trials to watch
Annie Tang & Toshifumi Yokota
Pages: 201-217
Published online: 06 Feb 2024
AbstractforDuchenne muscular dystrophy: promising early-stage clinical trials to watch | Full Text | References | PDF (3.1 MB) | EPUB
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Review Article
Drugs of the future for diarrhea-predominant irritable bowel syndrome: an overview of current investigational drugs
Shilan Mozaffari, Shekoufeh Nikfar & Mohammad Abdollahi
Pages: 219-228
Published online: 23 Feb 2024
AbstractforDrugs of the future for diarrhea-predominant irritable bowel syndrome: an overview of current investigational drugs | Full Text | References | PDF (313.5 KB) | EPUB
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Review Article
Enhancing anti-CD274 (PD-L1) targeting through combinatorial immunotherapy with bispecific antibodies and fusion proteins: from preclinical to phase II clinical trials
Dominik Kiem, Matthias Ocker, Richard Greil, Daniel Neureiter & Thomas Melchardt
Pages: 229-242
Published online: 23 Feb 2024
AbstractforEnhancing anti-CD274 (PD-L1) targeting through combinatorial immunotherapy with bispecific antibodies and fusion proteins: from preclinical to phase II clinical trials | Full Text | References | PDF (1.6 MB) | EPUB
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Review Article
Investigational pharmacological agents for the treatment of ARDS
Katyayini Aribindi, Michelle Lim, Satyan Lakshminrusimha & Timothy Albertson
Pages: 243-277
Published online: 27 Feb 2024
AbstractforInvestigational pharmacological agents for the treatment of ARDS | Full Text | References | PDF (3.9 MB) | EPUB
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Review Article
A modest proposal: targeting αv integrin-mediated activation of latent TGFbeta as a novel therapeutic approach to treat scleroderma fibrosis
Andrew Leask, Asmaa Fadl & Angha Naik
Pages: 279-285
Published online: 26 Feb 2024
AbstractforA modest proposal: targeting αv integrin-mediated activation of latent TGFbeta as a novel therapeutic approach to treat scleroderma fibrosis | Full Text | References | PDF (1.3 MB) | EPUB
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