Expert Opinion on Drug Metabolism & Toxicology, Volume 12, Issue 5 (2016)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 12, Issue 5 (2016)

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Editorial

Editorial
New technologies in drug metabolism and toxicity screening: organ-to-organ interaction
Abhinav Bhushan, Nicole J. Martucci, O. Berk Usta & Martin L. Yarmush
Pages: 475-477
Published online: 21 Mar 2016
First Page PreviewforNew technologies in drug metabolism and toxicity screening: organ-to-organ interaction | Full Text | References | PDF (251.3 KB)
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Free Access

Review

Review
CYP3A activity: towards dose adaptation to the individual
Nicolas Hohmann, Walter E. Haefeli & Gerd Mikus
Pages: 479-497
Published online: 26 Mar 2016
AbstractforCYP3A activity: towards dose adaptation to the individual | Full Text | References | PDF (2.1 MB) | Supplemental
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Review
ABC transporters at the blood–brain barrier
Anne Mahringer & Gert Fricker
Pages: 499-508
Published online: 04 Apr 2016
AbstractforABC transporters at the blood–brain barrier | Full Text | References | PDF (813.8 KB)
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Review
Current status and opportunities for therapeutic drug monitoring in the treatment of tuberculosis
Marlanka A. Zuur, Mathieu S. Bolhuis, Richard Anthony, Alice den Hertog, Tridia van der Laan, Bob Wilffert, Wiel de Lange, Dick van Soolingen & Jan-Willem C. Alffenaar
Pages: 509-521
Published online: 24 Mar 2016
AbstractforCurrent status and opportunities for therapeutic drug monitoring in the treatment of tuberculosis | Full Text | References | PDF (1.2 MB)
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Open Access
Review
Use of anticancer agents in gynecological oncology during pregnancy: a systematic review of maternal pharmacokinetics and transplacental transfer
Paul Berveiller, Oriane Marty, François Vialard & Olivier Mir
Pages: 523-531
Published online: 04 Apr 2016
AbstractforUse of anticancer agents in gynecological oncology during pregnancy: a systematic review of maternal pharmacokinetics and transplacental transfer | Full Text | References | PDF (702.8 KB)
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Review
Drug monitoring and individual dose optimization of antimicrobial drugs: oxazolidinones
Dario Cattaneo, Jan-Willem Alffenaar & Michael Neely
Pages: 533-544
Published online: 28 Mar 2016
AbstractforDrug monitoring and individual dose optimization of antimicrobial drugs: oxazolidinones | Full Text | References | PDF (1 MB)
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Review
Therapeutic drug monitoring of mycophenolate in adult solid organ transplant patients: an update
Tony K. L. Kiang & Mary H. H. Ensom
Pages: 545-553
Published online: 07 Apr 2016
AbstractforTherapeutic drug monitoring of mycophenolate in adult solid organ transplant patients: an update | Full Text | References | PDF (688 KB)
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Review
Pharmacogenetic aspects of the use of tacrolimus in renal transplantation: recent developments and ethnic considerations
J.T. Tang, L.M. Andrews, T. van Gelder, Y.Y. Shi, R.H.N. van Schaik, L.L. Wang & D.A. Hesselink
Pages: 555-565
Published online: 07 Apr 2016
AbstractforPharmacogenetic aspects of the use of tacrolimus in renal transplantation: recent developments and ethnic considerations | Full Text | References | PDF (885.1 KB)
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Open Access

Drug Evaluation

Article
Pharmacodynamics and pharmacokinetics of sodium zirconium cyclosilicate [ZS-9] in the treatment of hyperkalemia
David K. Packham & Mikhail Kosiborod
Pages: 567-573
Published online: 05 Apr 2016
AbstractforPharmacodynamics and pharmacokinetics of sodium zirconium cyclosilicate [ZS-9] in the treatment of hyperkalemia | Full Text | References | PDF (876.8 KB)
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Article
Pharmacodynamics, pharmacokinetics and clinical efficacy of apixaban in the treatment of thrombosis
Shiying Silvia Zheng, James J. H. Chong & Beng Hock Chong
Pages: 575-580
Published online: 01 Apr 2016
AbstractforPharmacodynamics, pharmacokinetics and clinical efficacy of apixaban in the treatment of thrombosis | Full Text | References | PDF (506.2 KB)
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Article
Overview of elagolix for the treatment of endometriosis
Gian Benedetto Melis, Manuela Neri, Valentina Corda, Maria Elena Malune, Bruno Piras, Silvia Pirarba, Stefano Guerriero, Marisa Orrù, Maurizio Nicola D’Alterio, Stefano Angioni & Anna Maria Paoletti
Pages: 581-588
Published online: 25 Apr 2016
AbstractforOverview of elagolix for the treatment of endometriosis | Full Text | References | PDF (653.9 KB)
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