Expert Opinion on Drug Metabolism & Toxicology, Volume 4, Issue 9 (2008)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 4, Issue 9 (2008)

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Reviews

Article
Whole body physiologically-based pharmacokinetic models: their use in clinical drug development
Andrea N Edginton PhD, Frank-Peter Theil PhD, Walter Schmitt PhD & Stefan Willmann PhD
Pages: 1143-1152
Published online: 24 Aug 2008
AbstractforWhole body physiologically-based pharmacokinetic models: their use in clinical drug development | Full Text | References | PDF (313.2 KB)
  • 1117 Views
  • 117 CrossRef citations
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Article
Modifications of human carboxylesterase for improved prodrug activation
Jason M Hatfield PhD, Monika Wierdl PhD, Randy M Wadkins PhD & Philip M Potter PhD
Pages: 1153-1165
Published online: 24 Aug 2008
AbstractforModifications of human carboxylesterase for improved prodrug activation | Full Text | References | PDF (689.1 KB)
  • 243 Views
  • 30 CrossRef citations
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Article
In silico prediction of substrate properties for ABC-multidrug transporters
Michael A Demel, R Schwaha, O Krämer, P Ettmayer, Eric EJ Haaksma & Gerhard F Ecker
Pages: 1167-1180
Published online: 24 Aug 2008
AbstractforIn silico prediction of substrate properties for ABC-multidrug transporters | Full Text | References | PDF (916.5 KB)
  • 411 Views
  • 43 CrossRef citations
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Article
Human cytochromes P450 in the metabolism of drugs: new molecular models of enzyme–substrate interactions
David FV Lewis & Yuko Ito
Pages: 1181-1186
Published online: 24 Aug 2008
AbstractforHuman cytochromes P450 in the metabolism of drugs: new molecular models of enzyme–substrate interactions | Full Text | References | PDF (852.2 KB)
  • 209 Views
  • 24 CrossRef citations
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Article
The use of inductively coupled plasma mass spectrometry as a detector in drug metabolism studies
Bente Gammelgaard PhD, Helle Rüsz Hansen PhD, Stefan Stürup PhD & Charlotte Møller MSc
Pages: 1187-1207
Published online: 24 Aug 2008
AbstractforThe use of inductively coupled plasma mass spectrometry as a detector in drug metabolism studies | Full Text | References | PDF (452.5 KB)
  • 227 Views
  • 45 CrossRef citations
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Drug Evaluations

Article
Treatment of leishmaniasis with miltefosine: 2008 status
Jonathan (Josh) Berman MD PhD FAAP
Pages: 1209-1216
Published online: 24 Aug 2008
AbstractforTreatment of leishmaniasis with miltefosine: 2008 status | Full Text | References | PDF (270.2 KB)
  • 172 Views
  • 64 CrossRef citations
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Drug Evaluation

Article
Pentostatin in chronic lymphocytic leukemia
Craig Sauter, Nicole Lamanna & Mark A Weiss
Pages: 1217-1222
Published online: 24 Aug 2008
AbstractforPentostatin in chronic lymphocytic leukemia | Full Text | References | PDF (256.6 KB)
  • 296 Views
  • 19 CrossRef citations
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Article
Riluzole in psychiatry: a systematic review of the literature
Carlos A Zarate Jr & Husseini K Manji
Pages: 1223-1234
Published online: 24 Aug 2008
AbstractforRiluzole in psychiatry: a systematic review of the literature | Full Text | References | PDF (282.1 KB)
  • 362 Views
  • 73 CrossRef citations
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Article
Clinical development of metformin extended-release tablets for type 2 diabetes: an overview
Sherwin L Schwartz MD, Toufigh Gordi PhD, Eddie Hou PhD, Marilou Cramer BS, Michelle Heritier PhD & Verne E Cowles PhD
Pages: 1235-1243
Published online: 24 Aug 2008
AbstractforClinical development of metformin extended-release tablets for type 2 diabetes: an overview | Full Text | References | PDF (326.4 KB)
  • 1132 Views
  • 12 CrossRef citations
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