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Expert Opinion on Drug Metabolism & Toxicology
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Volume 8, Issue 3

Expert Opinion on Drug Metabolism & Toxicology

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Cover image for Expert Opinion on Drug Metabolism & Toxicology, Volume 8, Issue 3, 2012

Expert Opinion on Drug Metabolism & Toxicology, Volume 8, Issue 3 (2012)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 8, Issue 3 (2012)

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Reviews

Review Article

Is the toxicity of anti-angiogenic drugs predictive of outcome? A review of hypertension and proteinuria as biomarkers of response to anti-angiogenic therapy

Laura Horsley, Kalena Marti & Gordon C. Jayson

Pages: 283-293

Published online: 30 Jan 2012

AbstractforIs the toxicity of anti-angiogenic drugs predictive of outcome? A review of hypertension and proteinuria as biomarkers of response to anti-angiogenic therapy | Full Text | References | PDF (218 KB)

375 Views
26 CrossRef citations
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Review Article

The effect of garlic supplements and phytochemicals on the ADMET properties of drugs

Katja Berginc PhD & Albin Kristl (Professor) PhD

Pages: 295-310

Published online: 08 Feb 2012

AbstractforThe effect of garlic supplements and phytochemicals on the ADMET properties of drugs | Full Text | References | PDF (397.8 KB)

377 Views
11 CrossRef citations
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Review Article

Interactions between antiepileptics and second-generation antipsychotics

Jose de Leon MD, Vincenza Santoro BSc, Concetta D'Arrigo BSc & Edoardo Spina MD, PhD

Pages: 311-334

Published online: 15 Feb 2012

AbstractforInteractions between antiepileptics and second-generation antipsychotics | Full Text | References | PDF (508.7 KB)

1977 Views
59 CrossRef citations
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Review Article

The primary role of hepatic metabolism in idiosyncratic drug-induced liver injury

David E Amacher

Pages: 335-347

Published online: 31 Jan 2012

AbstractforThe primary role of hepatic metabolism in idiosyncratic drug-induced liver injury | Full Text | References | PDF (233.6 KB)

1088 Views
46 CrossRef citations
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Review Article

Genetics or environment in drug transport: the case of organic anion transporting polypeptides and adverse drug reactions

John D Clarke (Post-Doctoral Research Associate) PhD & Nathan J Cherrington (Associate Professor) PhD

Pages: 349-360

Published online: 27 Jan 2012

AbstractforGenetics or environment in drug transport: the case of organic anion transporting polypeptides and adverse drug reactions | Full Text | References | PDF (298 KB)

405 Views
24 CrossRef citations
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Review Article

S2R^Pgrmc1: the cytochrome-related sigma-2 receptor that regulates lipid and drug metabolism and hormone signaling

Ikhlas S A Ahmed (Associate Researcher) PhD, Cora Chamberlain (Associate Researcher) & Rolf J Craven (Associate Professor) PhD

Pages: 361-370

Published online: 01 Feb 2012

AbstractforS2R^Pgrmc1: the cytochrome-related sigma-2 receptor that regulates lipid and drug metabolism and hormone signaling | Full Text | References | PDF (324.3 KB) | Supplemental

694 Views
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Review Article

Cytochrome P450 variations in different ethnic populations

Joseph McGraw (Assistant Professor of Pharmaceutical Sciences) PharmD MPH PhD BCPS & Donald Waller (Professor of Pharmacology and Toxicology) PhD DABT

Pages: 371-382

Published online: 31 Jan 2012

AbstractforCytochrome P450 variations in different ethnic populations | Full Text | References | PDF (319.3 KB)

3243 Views
201 CrossRef citations
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Drug Evaluation

Article

Saxagliptin plus metformin combination in patients with type 2 diabetes and renal impairment

André J Scheen

Pages: 383-394

Published online: 08 Feb 2012

Abstractfor Saxagliptin plus metformin combination in patients with type 2 diabetes and renal impairment | Full Text | References | PDF (260.7 KB)

829 Views
10 CrossRef citations
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