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Volume 8, Issue 5

Expert Opinion on Drug Metabolism & Toxicology

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Expert Opinion on Drug Metabolism & Toxicology, Volume 8, Issue 5 (2012)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 8, Issue 5 (2012)

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Vol 20, 2024 Vol 19, 2023 Vol 18, 2022 Vol 17, 2021 Vol 16, 2020 Vol 15, 2019 Vol 14, 2018 Vol 13, 2017 Vol 12, 2016 Vol 11, 2015 Vol 10, 2014 Vol 9, 2013 Volume 8, 2012 Vol 7, 2011 Vol 6, 2010 Vol 5, 2009 Vol 4, 2008 Vol 3, 2007 Vol 2, 2006 Vol 1, 2005

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Research Article

Article

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Page: 1

Published online: 19 Apr 2012

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Editorial

Predicting and detecting adverse drug reactions in old age: challenges and opportunities

Arduino A Mangoni (Professor of Medicine of Old Age) PhD FRACP FRCP

Pages: 527-530

Published online: 19 Apr 2012

AbstractforPredicting and detecting adverse drug reactions in old age: challenges and opportunities | Full Text | References | PDF (167.7 KB)

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Free Access

Reviews

Review Article

Strategies to minimize CNS toxicity: in vitro high-throughput assays and computational modeling

Travis T Wager, Jennifer L Liras, Scot Mente & Patrick Trapa

Pages: 531-542

Published online: 29 Mar 2012

AbstractforStrategies to minimize CNS toxicity: in vitro high-throughput assays and computational modeling | Full Text | References | PDF (532.3 KB)

701 Views
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Review Article

Metabolic, toxicological, and safety considerations for drugs used to treat ADHD

Sophie Duong BA, Kara Chung BA & Sharon B Wigal PhD

Pages: 543-552

Published online: 13 Mar 2012

AbstractforMetabolic, toxicological, and safety considerations for drugs used to treat ADHD | Full Text | References | PDF (217.5 KB)

1531 Views
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Review Article

Fluoroquinolone disposition: identification of the contribution of renal secretory and reabsorptive drug transporters

Aditi Mulgaonkar B Pharmacy, Jurgen Venitz (Associate Professor and Vice Chairman) MD PhD & Douglas H Sweet (Associate Professor) PhD

Pages: 553-569

Published online: 22 Mar 2012

AbstractforFluoroquinolone disposition: identification of the contribution of renal secretory and reabsorptive drug transporters | Full Text | References | PDF (391.6 KB)

528 Views
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Review Article

Xenobiotic-induced liver injury and fibrosis

Christoph H Österreicher & Michael Trauner (Professor and Chair of Gastroenterology and Hepatology) MD

Pages: 571-580

Published online: 28 Mar 2012

AbstractforXenobiotic-induced liver injury and fibrosis | Full Text | References | PDF (213.7 KB)

490 Views
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Review Article

Pharmacokinetics of recombinant bifunctional fusion proteins

Xiaoying Chen, Jennica L Zaro & Wei-Chiang Shen

Pages: 581-595

Published online: 20 Mar 2012

AbstractforPharmacokinetics of recombinant bifunctional fusion proteins | Full Text | References | PDF (421.7 KB)

509 Views
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Review Article

Role of microRNAs in the regulation of drug metabolizing and transporting genes and the response to environmental toxicants

Igor Koturbash MD PhD, Frederick A Beland & Igor P Pogribny

Pages: 597-606

Published online: 21 Mar 2012

AbstractforRole of microRNAs in the regulation of drug metabolizing and transporting genes and the response to environmental toxicants | Full Text | References | PDF (217.8 KB)

391 Views
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Review Article

Cell-based in vitro models for predicting drug permeability

Bruno Sarmento, Fernanda Andrade, Sara Baptista da Silva, Francisca Rodrigues, José das Neves & Domingos Ferreira

Pages: 607-621

Published online: 18 Mar 2012

AbstractforCell-based in vitro models for predicting drug permeability | Full Text | References | PDF (592.5 KB)

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Drug Evaluations

Article

Perifosine, an oral, anti-cancer agent and inhibitor of the Akt pathway: mechanistic actions, pharmacodynamics, pharmacokinetics, and clinical activity

Paul G Richardson MD, Cathy Eng (Associate Professor, Associate Director of the Colorectal Center) MD FACP, Jill Kolesar PharmD, Teru Hideshima MD & Kenneth C Anderson MD

Pages: 623-633

Published online: 19 Apr 2012

Abstractfor Perifosine, an oral, anti-cancer agent and inhibitor of the Akt pathway: mechanistic actions, pharmacodynamics, pharmacokinetics, and clinical activity | Full Text | References | PDF (321 KB)

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Expert Opinion on Drug Metabolism & Toxicology (Vol.8, Iss.5, 2012)

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