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Expert Opinion on Drug Metabolism & Toxicology

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Expert Opinion on Drug Metabolism & Toxicology, Volume 8, Issue 7 (2012)

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Expert Opinion on Drug Metabolism & Toxicology, Volume 8, Issue 7 (2012)

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Research Article

Article

Page: 1

Published online: 16 Jun 2012

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Reviews

Review Article

The pharmacogenetics of β-adrenergic receptor antagonists in the treatment of hypertension and heart failure

Sze Wa Chan, Miao Hu & Brian Tomlinson (Professor)

Pages: 767-790

Published online: 24 May 2012

AbstractforThe pharmacogenetics of β-adrenergic receptor antagonists in the treatment of hypertension and heart failure | Full Text | References | PDF (409.3 KB)

622 Views
12 CrossRef citations
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Review Article

Web tools for predictive toxicology model building

Nina Jeliazkova PhD

Pages: 791-801

Published online: 12 May 2012

AbstractforWeb tools for predictive toxicology model building | Full Text | References | PDF (239.5 KB)

312 Views
7 CrossRef citations
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Review Article

Role of CAR and PXR in xenobiotic sensing and metabolism

Yue-Ming Wang (Postdoctoral Research Associate) PhD, Su Sien Ong (Postdoctoral Research Associate) PhD, Sergio C Chai (Senior Research Technologist) PhD & Taosheng Chen (Associate Member) PhD

Pages: 803-817

Published online: 03 May 2012

AbstractforRole of CAR and PXR in xenobiotic sensing and metabolism | Full Text | References | PDF (514.3 KB)

1050 Views
174 CrossRef citations
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Review Article

Metabolic and toxicological considerations of botanicals in anticancer therapy

Carmela Fimognari, Lorenzo Ferruzzi, Eleonora Turrini, Giovanni Carulli, Monia Lenzi, Patrizia Hrelia & Giorgio Cantelli-Forti

Pages: 819-832

Published online: 27 Apr 2012

AbstractforMetabolic and toxicological considerations of botanicals in anticancer therapy | Full Text | References | PDF (311.3 KB)

227 Views
14 CrossRef citations
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Review Article

Regioselective biotransformation of CNS drugs and its clinical impact on adverse drug reactions

Yin Cheong Wong BPharm, RPh, Shuai Qian MPhil & Zhong Zuo (Professor) PhD

Pages: 833-854

Published online: 08 May 2012

AbstractforRegioselective biotransformation of CNS drugs and its clinical impact on adverse drug reactions | Full Text | References | PDF (636 KB)

283 Views
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Review Article

Prediction of volume of distribution at steady state in humans: comparison of different approaches

Peng Zou, Nan Zheng, Yongsheng Yang (Senior Pharmacologist, Office of Testing and Research) , Lawrence X Yu (Director for Science, Office of Generic Drugs) & Duxin Sun PhD

Pages: 855-872

Published online: 17 May 2012

AbstractforPrediction of volume of distribution at steady state in humans: comparison of different approaches | Full Text | References | PDF (414.7 KB)

1182 Views
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Drug Evaluations

Article

Oral paliperidone extended-release: chemistry, pharmacodynamics, pharmacokinetics and metabolism, clinical efficacy, safety and tolerability

Leslie Citrome MD MPH

Pages: 873-888

Published online: 25 May 2012

AbstractforOral paliperidone extended-release: chemistry, pharmacodynamics, pharmacokinetics and metabolism, clinical efficacy, safety and tolerability | Full Text | References | PDF (306.8 KB)

872 Views
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Article

Pharmacokinetic evaluation of rivaroxaban for the treatment of acute coronary syndromes

Lakshmi Gopalakrishnan MBBS, Varun Kumar MBBS, Payal Kohli MD, Priyamvada Singh MBBS, Ujjwal Rastogi MBBS & C. Michael Gibson MS MD

Pages: 889-900

Published online: 11 May 2012

AbstractforPharmacokinetic evaluation of rivaroxaban for the treatment of acute coronary syndromes | Full Text | References | PDF (286.3 KB)

573 Views
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Article

Pharmacokinetic evaluation of ulipristal acetate for uterine leiomyoma treatment

Gian Benedetto Melis MD, Bruno Piras MD, Maria Francesca Marotto MD, Marisa Margherita Orru' PhDGiovanni Maricosu MD, Monica Pilloni MD, Stefano Guerriero MD, Marco Angiolucci MD, Stefano Lello MD & Anna Maria Paoletti MD

Pages: 901-908

Published online: 10 Jun 2012

AbstractforPharmacokinetic evaluation of ulipristal acetate for uterine leiomyoma treatment | Full Text | References | PDF (225.6 KB)

372 Views
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Technology Evaluation

Article

The HepaRG cell line: a unique in vitro tool for understanding drug metabolism and toxicology in human

Tommy B Andersson (Senior Principal Scientist) PhD, Kajsa P Kanebratt (Senior Research Scientist) PhD & John Gerry Kenna (Principal Scientist) PhD

Pages: 909-920

Published online: 08 May 2012

AbstractforThe HepaRG cell line: a unique in vitro tool for understanding drug metabolism and toxicology in human | Full Text | References | PDF (551.8 KB)

2633 Views
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