Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 28, Issue 2 (2013)

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Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 28, Issue 2 (2013)

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Editorial

Editorial
Carbonic anhydrases: from biomedical applications of the inhibitors and activators to biotechnological use for CO2 capture
Claudiu T. Supuran
Pages: 229-230
Published online: 05 Feb 2013
CitationforCarbonic anhydrases: from biomedical applications of the inhibitors and activators to biotechnological use for CO2 capture | Full Text | References | PDF (569.2 KB)
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Review Article

Review Article
Carbonic anhydrase III: A neglected isozyme is stepping into the limelight
Anna-Kaisa Harju, Fatemeh Bootorabi, Marianne Kuuslahti, Claudiu T. Supuran & Seppo Parkkila
Pages: 231-239
Published online: 18 Jul 2012
AbstractforCarbonic anhydrase III: A neglected isozyme is stepping into the limelight | Full Text | References | PDF (1.1 MB)
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Review Article
Medicinal significance of benzothiazole scaffold: an insight view
Prabodh Chander Sharma, Alka Sinhmar, Archana Sharma, Harish Rajak & Dharam Pal Pathak
Pages: 240-266
Published online: 03 Oct 2012
AbstractforMedicinal significance of benzothiazole scaffold: an insight view | Full Text | References | PDF (9.9 MB)
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Review Article
Structural annotation of human carbonic anhydrases
Mayank Aggarwal, Christopher D. Boone, Bhargav Kondeti & Robert McKenna
Pages: 267-277
Published online: 09 Nov 2012
AbstractforStructural annotation of human carbonic anhydrases | Full Text | References | PDF (1.5 MB)
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Research Article

Article
Heavy metal ion inhibition studies of human, sheep and fish α-carbonic anhydrases
Ramazan Demirdağ, Emrah Yerlikaya, Murat Şentürk, Ö. İrfan Küfrevioğlu & Claudiu T. Supuran
Pages: 278-282
Published online: 07 Dec 2011
AbstractforHeavy metal ion inhibition studies of human, sheep and fish α-carbonic anhydrases | Full Text | References | PDF (625.5 KB)
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Article
Carbonic anhydrase inhibitors: in vitro inhibition of α isoforms (hCA I, hCA II, bCA III, hCA IV) by flavonoids
Derya Ekinci, Lutfi Karagoz, Deniz Ekinci, Murat Senturk & Claudiu T. Supuran
Pages: 283-288
Published online: 14 Dec 2011
AbstractforCarbonic anhydrase inhibitors: in vitro inhibition of α isoforms (hCA I, hCA II, bCA III, hCA IV) by flavonoids | Full Text | References | PDF (671 KB)
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Article
Three new aromatic sulfonamide inhibitors of carbonic anhydrases I, II, IV and XII
C. T. Supuran, A. Maresca, F. Gregáň & M. Remko
Pages: 289-293
Published online: 03 Feb 2012
AbstractforThree new aromatic sulfonamide inhibitors of carbonic anhydrases I, II, IV and XII | Full Text | References | PDF (633.7 KB)
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Article
Secondary/tertiary benzenesulfonamides with inhibitory action against the cytosolic human carbonic anhydrase isoforms I and II
Cemalettin Alp, Alfonso Maresca, Nurdan Alcan Alp, Mehmet Serdar Gültekin, Deniz Ekinci, Andrea Scozzafava & Claudiu T. Supuran
Pages: 294-298
Published online: 01 Mar 2012
AbstractforSecondary/tertiary benzenesulfonamides with inhibitory action against the cytosolic human carbonic anhydrase isoforms I and II | Full Text | References | PDF (693.1 KB)
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Article
Synthesis and carbonic anhydrase inhibitory properties of novel coumarin derivatives
Mert Olgun Karatas, Bülent Alici, Umit Cakir, Engin Cetinkaya, Dudu Demir, Adem Ergün, Nahit Gençer & Oktay Arslan
Pages: 299-304
Published online: 18 Apr 2012
AbstractforSynthesis and carbonic anhydrase inhibitory properties of novel coumarin derivatives | Full Text | References | PDF (656.3 KB) | Supplemental
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Article
2-Amino-3-cyanopyridine derivatives as carbonic anhydrase inhibitors
Selçuk Ayvaz, Murat Çankaya, Ali Atasever & Aliye Altuntas
Pages: 305-310
Published online: 05 Dec 2011
Abstractfor2-Amino-3-cyanopyridine derivatives as carbonic anhydrase inhibitors | Full Text | References | PDF (1.2 MB)
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Article
Synthesis and characterization of metal complexes of heterocyclic sulfonamide as carbonic anhydrase inhibitors
Nurgün Büyükkıdan, Metin Bülbül, Rahmi Kasımoğulları & Bülent Büyükkıdan
Pages: 311-315
Published online: 07 Sep 2012
AbstractforSynthesis and characterization of metal complexes of heterocyclic sulfonamide as carbonic anhydrase inhibitors | Full Text | References | PDF (646.8 KB) | Supplemental
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Article
Inhibition of mammalian carbonic anhydrase isoforms I, II and VI with thiamine and thiamine-like molecules
Zafer Ömer Özdemir, Murat Şentürk & Deniz Ekinci
Pages: 316-319
Published online: 06 Dec 2011
AbstractforInhibition of mammalian carbonic anhydrase isoforms I, II and VI with thiamine and thiamine-like molecules | Full Text | References | PDF (627.3 KB)
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Article
Docking, CoMFA and CoMSIA studies of a series of sulfonamides derivatives as carbonic anhydrase I inhibitors
Jahan B. Ghasemi & Nastaran Meftahi
Pages: 320-327
Published online: 06 Dec 2011
AbstractforDocking, CoMFA and CoMSIA studies of a series of sulfonamides derivatives as carbonic anhydrase I inhibitors | Full Text | References | PDF (834.8 KB) | Supplemental
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Article
Inhibitory effect of novel pyrazole carboxamide derivatives on human carbonic anhydrase enzyme
Elvan Şen, Zuhal Alım, Hatice Duran, Mehmet Mustafa İşgör, Şükrü Beydemir, Rahmi Kasımoğulları & Salim Ok
Pages: 328-336
Published online: 03 Feb 2012
AbstractforInhibitory effect of novel pyrazole carboxamide derivatives on human carbonic anhydrase enzyme | Full Text | References | PDF (762.3 KB)
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Article
Synthesis and characterization of phenolic Mannich bases and effects of these compounds on human carbonic anhydrase isozymes I and II
Nurgün Büyükkıdan, Bülent Büyükkıdan, Metin Bülbül, Salih Özer & Hatice Gonca Yalçın
Pages: 337-342
Published online: 20 Sep 2012
AbstractforSynthesis and characterization of phenolic Mannich bases and effects of these compounds on human carbonic anhydrase isozymes I and II | Full Text | References | PDF (707.7 KB)
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Article
Synthesis of aminocyanopyrazoles via a multi-component reaction and anti-carbonic anhydrase inhibitory activity of their sulfamide derivatives against cytosolic and transmembrane isoforms
Fatma Allouche, Fakher Chabchoub, Fabrizio Carta & Claudiu T. Supuran
Pages: 343-349
Published online: 27 Sep 2012
AbstractforSynthesis of aminocyanopyrazoles via a multi-component reaction and anti-carbonic anhydrase inhibitory activity of their sulfamide derivatives against cytosolic and transmembrane isoforms | Full Text | References | PDF (1.1 MB)
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Article
More effective dithiocarbamate derivatives inhibiting carbonic anhydrases, generated by QSAR and computational design
Speranta Avram, Adina Luminita Milac, Fabrizio Carta & Claudiu T. Supuran
Pages: 350-359
Published online: 01 Nov 2012
AbstractforMore effective dithiocarbamate derivatives inhibiting carbonic anhydrases, generated by QSAR and computational design | Full Text | References | PDF (843.1 KB)
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Article
Inhibition of carbonic anhydrase activity modifies the toxicity of doxorubicin and melphalan in tumour cells in vitro
Roben G. Gieling, Catriona A. Parker, Lisa A. De Costa, Naomi Robertson, Adrian L. Harris, Ian J. Stratford & Kaye J. Williams
Pages: 360-369
Published online: 19 Nov 2012
AbstractforInhibition of carbonic anhydrase activity modifies the toxicity of doxorubicin and melphalan in tumour cells in vitro | Full Text | References | PDF (850.7 KB)
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Article
Kinetic and in silico analysis of thiazolidin-based inhibitors of α-carbonic anhydrase isoenzymes
Deniz Ekinci, İsmail Fidan, Serdar Durdagi, Şeniz Kaban & Claudiu T. Supuran
Pages: 370-374
Published online: 23 Nov 2012
AbstractforKinetic and in silico analysis of thiazolidin-based inhibitors of α-carbonic anhydrase isoenzymes | Full Text | References | PDF (866.8 KB)
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Article
Quinazoline-sulfonamides as potential antitumor agents: synthesis and biological testing
Ahmed M. Alafeefy, Saleh I. Alqasoumi, Abdelkader E. Ashour & Mashael M. Alshebly
Pages: 375-383
Published online: 02 Apr 2012
AbstractforQuinazoline-sulfonamides as potential antitumor agents: synthesis and biological testing | Full Text | References | PDF (790 KB)
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Short Communications

Dihalogenated sulfanilamides and benzolamides are effective inhibitors of the three β-class carbonic anhydrases from Mycobacterium tuberculosis
Alfonso Maresca, Andrea Scozzafava, Daniela Vullo & Claudiu T. Supuran
Pages: 384-387
Published online: 03 Jan 2012
AbstractforDihalogenated sulfanilamides and benzolamides are effective inhibitors of the three β-class carbonic anhydrases from Mycobacterium tuberculosis | Full Text | References | PDF (647.1 KB)
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Inhibition of the alpha- and beta-carbonic anhydrases from the gastric pathogen Helycobacter pylori with anions
Alfonso Maresca, Daniela Vullo, Andrea Scozzafava,Claudiu T. Supuran
Pages: 388-391
Published online: 03 Feb 2012
AbstractforInhibition of the alpha- and beta-carbonic anhydrases from the gastric pathogen Helycobacter pylori with anions | Full Text | References | PDF (582 KB)
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Inhibition of the β-class carbonic anhydrases from Mycobacterium tuberculosis with carboxylic acids
Alfonso Maresca, Daniela Vullo, Andrea Scozzafava, Gheorghe Manole & Claudiu T. Supuran
Pages: 392-396
Published online: 03 Feb 2012
AbstractforInhibition of the β-class carbonic anhydrases from Mycobacterium tuberculosis with carboxylic acids | Full Text | References | PDF (609.8 KB)
  • 980 Views
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Metronidazole-coumarin conjugates and 3-cyano-7-hydroxy-coumarin act as isoform-selective carbonic anhydrase inhibitors
Adeline Bonneau, Alfonso Maresca, Jean-Yves Winum & Claudiu T. Supuran
Pages: 397-401
Published online: 03 Feb 2012
AbstractforMetronidazole-coumarin conjugates and 3-cyano-7-hydroxy-coumarin act as isoform-selective carbonic anhydrase inhibitors | Full Text | References | PDF (625.3 KB)
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(3,4-Dihydroxyphenyl)(2,3,4-trihydroxyphenyl)methanone and its derivatives as carbonic anhydrase isoenzymes inhibitors
Meryem Nar, Yasin Çetinkaya, İlhami Gülçin & Abdullah Menzek
Pages: 402-406
Published online: 02 Apr 2012
Abstractfor(3,4-Dihydroxyphenyl)(2,3,4-trihydroxyphenyl)methanone and its derivatives as carbonic anhydrase isoenzymes inhibitors | Full Text | References | PDF (648.2 KB)
  • 1024 Views
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Dithiocarbamates strongly inhibit the β-class carbonic anhydrases from Mycobacterium tuberculosis
Alfonso Maresca, Fabrizio Carta, Daniela Vullo & Claudiu T. Supuran
Pages: 407-411
Published online: 06 Dec 2011
AbstractforDithiocarbamates strongly inhibit the β-class carbonic anhydrases from Mycobacterium tuberculosis | Full Text | References | PDF (589.6 KB)
  • 1177 Views
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Analysis of saponins and phenolic compounds as inhibitors of α-carbonic anhydrase isoenzymes
Ömer Koz, Deniz Ekinci, Angela Perrone, Sonia Piacente, Özgen Alankuş-Çalışkan, Erdal Bedir & Claudiu T. Supuran
Pages: 412-417
Published online: 03 Feb 2012
AbstractforAnalysis of saponins and phenolic compounds as inhibitors of α-carbonic anhydrase isoenzymes | Full Text | References | PDF (672.9 KB)
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