Expert Opinion on Therapeutic Targets, Volume 15, Issue 12 (2011)

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Expert Opinion on Therapeutic Targets, Volume 15, Issue 12 (2011)

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Original Research

Article
Thymus peptides regulate activity of RAW 264.7 macrophage cells: inhibitory analysis and a role of signal cascades
Sergey M. Lunin, Olga V. Glushkova, Maxim O. Khrenov, Svetlana B. Parfenyuk, Tatyana V. Novoselova, Evgeny E. Fesenko & Elena G. Novoselova
Pages: 1337-1346
Published online: 09 Dec 2011
AbstractforThymus peptides regulate activity of RAW 264.7 macrophage cells: inhibitory analysis and a role of signal cascades | Full Text | References | PDF (488.5 KB)
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Article
Relationships of osteoprotegerin with albuminuria and asymmetric dimethylarginine in essential hypertension: integrating vascular dysfunction
Costas Tsioufis, Athanasios Aggelis, Kyriakos Dimitriadis, Costas Thomopoulos, Alexandros Kasiakogias, Vanessa Tzamou, Stella-Maria Kyvelou, Dimitri P. Mikhailidis, Vasilios Papademetriou & Christodoulos Stefanadis
Pages: 1347-1353
Published online: 03 Dec 2011
AbstractforRelationships of osteoprotegerin with albuminuria and asymmetric dimethylarginine in essential hypertension: integrating vascular dysfunction | Full Text | References | PDF (255.2 KB)
  • 62 Views
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Reviews

Review Article
Are we moving in the right direction with osteoarthritis drug discovery?
Jan Bondeson MD PhD
Pages: 1355-1368
Published online: 16 Nov 2011
AbstractforAre we moving in the right direction with osteoarthritis drug discovery? | Full Text | References | PDF (437.8 KB)
  • 566 Views
  • 20 CrossRef citations
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Review Article
Therapies using anti-angiogenic peptide mimetics of thrombospondin-1
Jack Henkin PhD & Olga V Volpert PhD
Pages: 1369-1386
Published online: 05 Dec 2011
AbstractforTherapies using anti-angiogenic peptide mimetics of thrombospondin-1 | Full Text | References | PDF (504.5 KB) | Supplemental
  • 884 Views
  • 42 CrossRef citations
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Review Article
Convergent mechanisms in etiologically-diverse dystonias
Valerie B Thompson PhD, H A Jinnah MD PhD & Ellen J Hess PhD
Pages: 1387-1403
Published online: 03 Dec 2011
AbstractforConvergent mechanisms in etiologically-diverse dystonias | Full Text | References | PDF (363.6 KB)
  • 220 Views
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Review Article
Advances in the design and synthesis of prazosin derivatives over the last ten years
Andreas Desiniotis & Natasha Kyprianou
Pages: 1405-1418
Published online: 13 Dec 2011
AbstractforAdvances in the design and synthesis of prazosin derivatives over the last ten years | Full Text | References | PDF (428 KB)
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Key Paper Evaluation

Article
Lemur tyrosine kinase-3 (LMTK3) as a target in oestrogen positive breast cancer
Evaluation of Giamas G, Filipović A, Jacob J, et al. Kinome screening for regulators of the estrogen receptor identifies LMTK3 as a new therapeutic target in breast cancer. Nat Med 2011;17:715-19, and Stebbing J, Filipovic A, Ellis IO, et al. LMTK3 expression in breast cancer: association with tumour phenotype and clinical outcome. Breast Cancer Res Treat 2011. [Epub ahead of print]
Sheila A Doggrell PhD DSc
Pages: 1419-1422
Published online: 28 Oct 2011
AbstractforLemur tyrosine kinase-3 (LMTK3) as a target in oestrogen positive breast cancer | Full Text | References | PDF (165.5 KB)
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Letter to the Editor

Letter
Ketamine may exert antidepressant effects via mediating the kynurenine pathway
Chun Yang, Zhiqiang Zhou, Jinyun Shi & Jianjun Yang
Pages: 1423-1424
Published online: 30 Nov 2011
CitationforKetamine may exert antidepressant effects via mediating the kynurenine pathway | Full Text | References | PDF (141.3 KB)
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