Expert Opinion on Therapeutic Targets, Volume 19, Issue 6 (2015)

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Expert Opinion on Therapeutic Targets, Volume 19, Issue 6 (2015)

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Editorial

Editorial
Subcellular G-protein coupled receptor signaling hints at greater therapeutic selectivity
Jean-Sébastien Joyal MD PhD, Vikrant K Bhosle & Sylvain Chemtob MD PhD
Pages: 717-721
Published online: 14 May 2015
AbstractforSubcellular G-protein coupled receptor signaling hints at greater therapeutic selectivity | Full Text | References | PDF (271.1 KB)
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Free Access

Original Research

Article
Neutralizations of IL-17A and IL-21 regulate regulatory T cell/T-helper 17 imbalance via T-helper 17-associated signaling pathway in immune thrombocytopenia
Yu Hu, Xiuwen Wang, Shuang Yu, Yu Hou, Daoxin Ma & Ming Hou
Pages: 723-732
Published online: 14 May 2015
AbstractforNeutralizations of IL-17A and IL-21 regulate regulatory T cell/T-helper 17 imbalance via T-helper 17-associated signaling pathway in immune thrombocytopenia | Full Text | References | PDF (788.1 KB) | Supplemental
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Article
Overexpression of pyruvate dehydrogenase kinase supports dichloroacetate as a candidate for cutaneous melanoma therapy
Helena Pópulo, Regina Caldas, José Manuel Lopes, Joana Pardal, Valdemar Máximo & Paula Soares
Pages: 733-745
Published online: 14 May 2015
AbstractforOverexpression of pyruvate dehydrogenase kinase supports dichloroacetate as a candidate for cutaneous melanoma therapy | Full Text | References | PDF (861.2 KB)
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Review

Sleep- and circadian rhythm–associated pathways as therapeutic targets in bipolar disorder
Frank Bellivier MD PhD, Pierre-Alexis Geoffroy MD, Bruno Etain MD PhD & Jan Scott MBBS PhD
Pages: 747-763
Published online: 02 Mar 2015
AbstractforSleep- and circadian rhythm–associated pathways as therapeutic targets in bipolar disorder | Full Text | References | PDF (428.7 KB)
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HIV-1 gp120 as a therapeutic target: navigating a moving labyrinth
Priyamvada Acharya (Research Scientist) PhD, Sabrina Lusvarghi (Research Fellow) PhD, Carole A Bewley (Senior Investigator) PhD & Peter D Kwong (Chief) PhD
Pages: 765-783
Published online: 27 Feb 2015
AbstractforHIV-1 gp120 as a therapeutic target: navigating a moving labyrinth | Full Text | References | PDF (880.8 KB)
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The role for IGF-1-derived small neuropeptides as a therapeutic target for neurological disorders
Jian Guan, Paul Harris, Margaret Brimble, Yang Lei, Jun Lu, Yang Yang & Alistair J Gunn
Pages: 785-793
Published online: 05 Feb 2015
AbstractforThe role for IGF-1-derived small neuropeptides as a therapeutic target for neurological disorders | Full Text | References | PDF (354.3 KB)
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Targeting EGFR-PI3K-AKT-mTOR signaling enhances radiosensitivity in head and neck squamous cell carcinoma
Dominik Horn, Jochen Hess, Kolja Freier, Jürgen Hoffmann & Christian Freudlsperger
Pages: 795-805
Published online: 05 Feb 2015
AbstractforTargeting EGFR-PI3K-AKT-mTOR signaling enhances radiosensitivity in head and neck squamous cell carcinoma | Full Text | References | PDF (511.4 KB)
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Angiogenesis in salivary gland tumors: from clinical significance to treatment
Stamatios Theocharis, George Gribilas, Constantinos Giaginis (Assistant Professor of Human Physiology) , Efstratios Patsouris & Jerzy Klijanienko
Pages: 807-819
Published online: 08 May 2015
AbstractforAngiogenesis in salivary gland tumors: from clinical significance to treatment | Full Text | References | PDF (280.1 KB)
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Breast cancer treatment and sulfotransferase
Xi-Wei Ji, Tian-Yan Zhou, Yuan Lu, Min-Ji Wei, Wei Lu & William C Cho
Pages: 821-834
Published online: 12 Feb 2015
AbstractforBreast cancer treatment and sulfotransferase | Full Text | References | PDF (637.5 KB)
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Targeting the thyroid-stimulating hormone receptor with small molecule ligands and antibodies
Terry F Davies & Rauf Latif
Pages: 835-847
Published online: 13 Mar 2015
AbstractforTargeting the thyroid-stimulating hormone receptor with small molecule ligands and antibodies | Full Text | References | PDF (635.4 KB)
  • 444 Views
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The influence of the telomere-telomerase system on diabetes mellitus and its vascular complications
Wu Qi Nan, Zhang Ling & Chen Bing
Pages: 849-864
Published online: 13 Feb 2015
AbstractforThe influence of the telomere-telomerase system on diabetes mellitus and its vascular complications | Full Text | References | PDF (610.8 KB)
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Further Readings

Related articles
Page: 1
Published online: 14 May 2015
CitationforRelated articles | Full Text | PDF (84.5 KB)
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