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Volume 19, Issue 7

Expert Opinion on Therapeutic Targets

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Expert Opinion on Therapeutic Targets, Volume 19, Issue 7 (2015)

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Expert Opinion on Therapeutic Targets, Volume 19, Issue 7 (2015)

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Editorial

Is there potential to target FOXM1 for ‘undruggable’ lung cancers?

Vladimir V Kalinichenko & Tanya V Kalin

Pages: 865-867

Published online: 04 May 2015

AbstractforIs there potential to target FOXM1 for ‘undruggable’ lung cancers? | Full Text | References | PDF (129.5 KB)

1941 Views
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Free Access

Review

Novel therapeutic targets of metformin: metabolic syndrome and cardiovascular disease

Ricardo Ladeiras-Lopes MD, Ricardo Fontes-Carvalho MD, Nuno Bettencourt MD PhD, Francisco Sampaio MD PhD, Vasco Gama MD & Adelino Leite-Moreira MD PhD

Pages: 869-877

Published online: 11 Mar 2015

AbstractforNovel therapeutic targets of metformin: metabolic syndrome and cardiovascular disease | Full Text | References | PDF (434.7 KB)

906 Views
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Non-NMDAR neuronal Ca²⁺–permeable channels in delayed neuronal death and as potential therapeutic targets for ischemic brain damage

Chaokun Li, Li Meng, Xin Li, Dongliang Li & Lin-Hua Jiang

Pages: 879-892

Published online: 02 Mar 2015

AbstractforNon-NMDAR neuronal Ca²⁺–permeable channels in delayed neuronal death and as potential therapeutic targets for ischemic brain damage | Full Text | References | PDF (430.9 KB)

336 Views
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Leptin signaling as a therapeutic target of obesity

Neira Sáinz, Carlos J González-Navarro, J Alfredo Martínez & Maria J Moreno-Aliaga

Pages: 893-909

Published online: 01 Mar 2015

AbstractforLeptin signaling as a therapeutic target of obesity | Full Text | References | PDF (475.5 KB)

764 Views
23 CrossRef citations
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Are big potassium-type Ca²⁺-activated potassium channels a viable target for the treatment of epilepsy?

Antonio Leo, Rita Citraro, Andrew Constanti, Giovambattista De Sarro (Professor, Chair of Pharmacology) MD & Emilio Russo

Pages: 911-926

Published online: 03 Apr 2015

AbstractforAre big potassium-type Ca²⁺-activated potassium channels a viable target for the treatment of epilepsy? | Full Text | References | PDF (433.8 KB)

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Homocysteine as a potential biomarker in bipolar disorders: a critical review and suggestions for improved studies

Ahmad Ghanizadeh (Psychiatrist) MD, Ajeet B Singh MBBS MPsych MD FRANZCP, Michael Berk (Psychiatrist) MBBCh MMed (Psych) FF(Psych)SA PhD FRANZCP & Mohammad Torabi-Nami MD PhD

Pages: 927-939

Published online: 16 Apr 2015

AbstractforHomocysteine as a potential biomarker in bipolar disorders: a critical review and suggestions for improved studies | Full Text | References | PDF (312.5 KB)

326 Views
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Receptor tyrosine kinase-like orphan receptor 1: a novel target for cancer immunotherapy

Mahdi Shabani PhD, Jila Naseri MD & Fazel Shokri PhD

Pages: 941-955

Published online: 02 Apr 2015

AbstractforReceptor tyrosine kinase-like orphan receptor 1: a novel target for cancer immunotherapy | Full Text | References | PDF (504.7 KB)

1325 Views
31 CrossRef citations
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The centrosome: a prospective entrant in cancer therapy

Jubina B Venghateri, Bhavya Jindal & Dulal Panda

Pages: 957-972

Published online: 18 Mar 2015

AbstractforThe centrosome: a prospective entrant in cancer therapy | Full Text | References | PDF (782.8 KB)

396 Views
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Novel therapeutic targets and predictive markers for hepatocellular carcinoma

Stephen L Chan, Anthony WH Chan & Winnie Yeo

Pages: 973-983

Published online: 24 Apr 2015

AbstractforNovel therapeutic targets and predictive markers for hepatocellular carcinoma | Full Text | References | PDF (516.8 KB)

489 Views
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Original Research

Article

Decrease of phosphorylated proto-oncogene CREB at Ser 133 site inhibits growth and metastatic activity of renal cell cancer

Xue Wang, Yu Ren, Haihui Zhuang, Xiangyu Meng, Shuaishuai Huang, Yanyuan Li, Michael Hehir & Ping Wang

Pages: 985-995

Published online: 03 Jun 2015

AbstractforDecrease of phosphorylated proto-oncogene CREB at Ser 133 site inhibits growth and metastatic activity of renal cell cancer | Full Text | References | PDF (931.9 KB)

259 Views
15 CrossRef citations
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Article

Polydatin protects hepatocytes against mitochondrial injury in acute severe hemorrhagic shock via SIRT1-SOD₂ pathway

Pengyun Li, Xingmin Wang, Ming Zhao MD, Rui Song MD PhD & Ke-seng Zhao

Pages: 997-1010

Published online: 15 Jun 2015

AbstractforPolydatin protects hepatocytes against mitochondrial injury in acute severe hemorrhagic shock via SIRT1-SOD₂ pathway | Full Text | References | PDF (1.3 MB) | Supplemental

275 Views
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