Expert Opinion on Therapeutic Targets, Volume 25, Issue 12 (2021)

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Expert Opinion on Therapeutic Targets, Volume 25, Issue 12 (2021)

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Editorial

Editorial
Anti-cataract therapies: is there a need for a new approach based on targeting of aquaporins?
Barbara K. Pierscionek
Pages: 1027-1031
Published online: 30 Dec 2021
First Page PreviewforAnti-cataract therapies: is there a need for a new approach based on targeting of aquaporins? | Full Text | References | PDF (197.1 KB) | EPUB
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Review

PNPLA3 as a therapeutic target for fatty liver disease: the evidence to date
Alessandro Cherubini, Elia Casirati, Melissa Tomasi & Luca Valenti
Pages: 1033-1043
Published online: 22 Dec 2021
AbstractforPNPLA3 as a therapeutic target for fatty liver disease: the evidence to date | Full Text | References | PDF (2.8 MB) | EPUB
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Potential of IDH mutations as immunotherapeutic targets in gliomas: a review and meta-analysis
Nazareno Gonzalez, Antonela S. Asad, José Gómez Escalante, Jorge A. Peña Agudelo, Alejandro J. Nicola Candia, Matías García Fallit, Adriana Seilicovich & Marianela Candolfi
Pages: 1045-1060
Published online: 04 Jan 2022
AbstractforPotential of IDH mutations as immunotherapeutic targets in gliomas: a review and meta-analysis | Full Text | References | PDF (10 MB) | EPUB
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Novel therapeutic targets for diabetes-related wounds or ulcers: an update on preclinical and clinical research
Jonathan Golledge & Shivshankar Thanigaimani
Pages: 1061-1075
Published online: 22 Dec 2021
AbstractforNovel therapeutic targets for diabetes-related wounds or ulcers: an update on preclinical and clinical research | Full Text | References | PDF (1.5 MB) | EPUB
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Glycometabolic rearrangements–aerobic glycolysis in pancreatic ductal adenocarcinoma (PDAC): roles, regulatory networks, and therapeutic potential
Zhong Zhang & Hai-Jun Zhang
Pages: 1077-1093
Published online: 20 Dec 2021
AbstractforGlycometabolic rearrangements–aerobic glycolysis in pancreatic ductal adenocarcinoma (PDAC): roles, regulatory networks, and therapeutic potential | Full Text | References | PDF (4.6 MB) | EPUB
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Original Research

Article
Molecular characterization of extrahepatic cholangiocarcinoma: perihilar and distal tumors display divergent genomic and transcriptomic profiles
Michele Simbolo, Samantha Bersani, Caterina Vicentini, Sergio V. Taormina, Chiara Ciaparrone, Fabio Bagante, Borislav Rusev, Giovanni Centonze, Marina Montresor, Matteo Brunelli, Serena Pedron, Andrea Mafficini, Gaetano Paolino, Paola Mattiolo, Simone Conci, Massimo Milione, Alfredo Guglielmi, Andrea Ruzzenente, Aldo Scarpa & Claudio Luchini
Pages: 1095-1105
Published online: 22 Dec 2021
AbstractforMolecular characterization of extrahepatic cholangiocarcinoma: perihilar and distal tumors display divergent genomic and transcriptomic profiles | Full Text | References | PDF (4.9 MB) | EPUB | Supplemental
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