Future Medicinal Chemistry, Volume 11, Issue 10 (2019)

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Future Medicinal Chemistry, Volume 11, Issue 10 (2019)

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Editorial

Editorial
Therapeutic Opportunity in Innate Immune Response Induction by Oncogene-Targeted Drugs
Daniel J Sisler & Lynn E Heasley
Pages: 1083-1086
Published online: 14 May 2019
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Free Access

Commentary

Editorial
Use of Organoids in Medicinal Chemistry: Challenges on Ethics and Biosecurity
Teresa Rinaldi & Gianni Colotti
Pages: 1087-1090
Published online: 08 Jul 2019
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Research Article

Article
Synthesis and Biological Evaluation of Aza-Crown Ether–Squaramide Conjugates as Anion/Cation Symporters
Xi-Hui Yu, Xiong-Jie Cai, Xiao-Qiao Hong, Kin Yip Tam, Kun Zhang & Wen-Hua Chen
Pages: 1091-1106
Published online: 08 Jul 2019
AbstractforSynthesis and Biological Evaluation of Aza-Crown Ether–Squaramide Conjugates as Anion/Cation Symporters | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
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Article
Hit Identification of SMYD3 Enzyme Inhibitors Using Structure-Based Pharmacophore Modeling
Soraya M Alnabulsi & Nizar A Al-shar’i
Pages: 1107-1117
Published online: 08 Jul 2019
AbstractforHit Identification of SMYD3 Enzyme Inhibitors Using Structure-Based Pharmacophore Modeling | Full Text | References | PDF (4.9 MB) | EPUB | Supplemental
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Article
Discovery of Novel 1,2,4-triazolo-1,2,4-triazines with Thiomethylpyridine Hinge Binders as Potent c-Met Kinase Inhibitors
Sakineh Dadashpour, Tuba Tüylü Küçükkılınç, Beyza Ayazgök, Seyed Jalal Hosseinimehr, Ann M Chippindale, Alireza Foroumadi & Hamid Irannejad
Pages: 1119-1136
Published online: 08 Jul 2019
AbstractforDiscovery of Novel 1,2,4-triazolo-1,2,4-triazines with Thiomethylpyridine Hinge Binders as Potent c-Met Kinase Inhibitors | Full Text | References | PDF (1.3 MB) | EPUB | Supplemental
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Article
Novel [1,2,3]triazolo[1,5-a]pyridine Derivatives are Trypanocidal by Sterol Biosynthesis Pathway Alteration
Michel Lapier, Rafael Ballesteros-Garrido, Daniela Guzman-Rivera, Fabiola González-Herrera, Benjamin Aguilera-Venegas, Mauricio Moncada-Basualto, Rafael Ballesteros, Belén Abarca, Bárbara Pesce, Ulrike Kemmerling, Claudio Olea-Azar & Juan D Maya
Pages: 1137-1155
Published online: 08 Jul 2019
AbstractforNovel [1,2,3]triazolo[1,5-a]pyridine Derivatives are Trypanocidal by Sterol Biosynthesis Pathway Alteration | Full Text | References | PDF (5.3 MB) | EPUB | Supplemental
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Review

Review Article
Fluorinated MRI Contrast Agents and Their Versatile Applications in the Biomedical Field
Emilie Hequet, Céline Henoumont, Robert N Muller & Sophie Laurent
Pages: 1157-1175
Published online: 08 Jul 2019
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Review Article
Lipophilicity in Drug Design: An Overview of Lipophilicity Descriptors in 3D-QSAR Studies
Tiziana Ginex, Javier Vazquez, Enric Gilbert, Enric Herrero & Francisco J Luque
Pages: 1177-1193
Published online: 25 Feb 2019
AbstractforLipophilicity in Drug Design: An Overview of Lipophilicity Descriptors in 3D-QSAR Studies | Full Text | References | PDF (408.7 KB) | EPUB | Supplemental
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Review Article
Labelled Chemical Probes for Demonstrating Direct Target Engagement in Living Systems
Hugues Prevet & Ian Collins
Pages: 1195-1224
Published online: 08 Jul 2019
AbstractforLabelled Chemical Probes for Demonstrating Direct Target Engagement in Living Systems | Full Text | References | PDF (3.1 MB) | EPUB
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Open Access
Review Article
Exosome Manufacturing Status
William Whitford & Peter Guterstam
Pages: 1225-1236
Published online: 08 Jul 2019
AbstractforExosome Manufacturing Status | Full Text | References | PDF (1.8 MB) | EPUB
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