Future Medicinal Chemistry, Volume 11, Issue 4 (2019)

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Future Medicinal Chemistry, Volume 11, Issue 4 (2019)

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Editorial

Editorial
Multitarget-directed Ligands for Neurodegenerative Diseases: Real Opportunity Or Blurry mirage?
Mohamed Benchekroun & Samuele Maramai
Pages: 261-263
Published online: 14 Feb 2019
First Page PreviewforMultitarget-directed Ligands for Neurodegenerative Diseases: Real Opportunity Or Blurry mirage? | Full Text | References | PDF (168.6 KB) | EPUB
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Free Access

Commentary

Editorial
Designing Influenza Polymerase Acidic Endonuclease Inhibitors Via ‘privileged scaffold’ re-evolution/refining Strategy
Han Ju, Peng Zhan & Xinyong Liu
Pages: 265-268
Published online: 14 Feb 2019
First Page PreviewforDesigning Influenza Polymerase Acidic Endonuclease Inhibitors Via ‘privileged scaffold’ re-evolution/refining Strategy | Full Text | References | PDF (182.5 KB) | EPUB
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Research Article

Article
NBGNU: a hypoxia-activated Tripartite combi-nitrosourea Prodrug Overcoming AGT-mediated Chemoresistance
Yao Ge, Xinxin Lai, Jintao Li, Ran Yu, Zhuochen Zhuang, Guohui Sun, Xin Cui, Na Zhang, Lijiao Zhao, Pramod Upadhyaya & Rugang Zhong
Pages: 269-284
Published online: 18 Dec 2018
AbstractforNBGNU: a hypoxia-activated Tripartite combi-nitrosourea Prodrug Overcoming AGT-mediated Chemoresistance | Full Text | References | PDF (4.4 MB) | EPUB | Supplemental
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Open Access
Article
Benzodifurans for Biomedical Applications: BZ4, a Selective anti-proliferative and anti-amyloid Lead Compound
Caterina Vicidomini, Federica Cioffi, Kerensa Broersen, Valentina Roviello, Claudia Riccardi, Daniela Montesarchio, Domenica Capasso, Sonia Di Gaetano, Domenica Musumeci & Giovanni N Roviello
Pages: 285-302
Published online: 25 Feb 2019
AbstractforBenzodifurans for Biomedical Applications: BZ4, a Selective anti-proliferative and anti-amyloid Lead Compound | Full Text | References | PDF (5.2 MB) | EPUB | Supplemental
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Article
Improving the Accuracy of Predicting protein–ligand binding-free Energy With Semiempirical Quantum Chemistry Charge
Cheng Peng, Jinan Wang, Yuqi Yu, Guimin Wang, Zhaoqiang Chen, Zhijian Xu, Tingting Cai, Qiang Shao, Jiye Shi & Weiliang Zhu
Pages: 303-321
Published online: 25 Feb 2019
AbstractforImproving the Accuracy of Predicting protein–ligand binding-free Energy With Semiempirical Quantum Chemistry Charge | Full Text | References | PDF (8.8 MB) | EPUB | Supplemental
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Review

Review Article
Gaseous Signaling Molecules and Their Application in Resistant Cancer Treatment: From Invisible to Visible
Qingbin Cui, Yuqi Yang, Ning Ji, Jing-Quan Wang, Liang Ren, Dong-Hua Yang & Zhe-Sheng Chen
Pages: 323-336
Published online: 25 Feb 2019
AbstractforGaseous Signaling Molecules and Their Application in Resistant Cancer Treatment: From Invisible to Visible | Full Text | References | PDF (2.1 MB) | EPUB
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Review Article
How to Replace the Lost keys? Strategies Toward Safer KV7 Channel Openers
Christian Bock & Andreas Link
Pages: 337-355
Published online: 25 Feb 2019
AbstractforHow to Replace the Lost keys? Strategies Toward Safer KV7 Channel Openers | Full Text | References | PDF (3.2 MB) | EPUB
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Review Article
Hydroxylation of Protein Constituents of the Human Translation System: Structural Aspects and Functional Assignments
Dmitri Graifer, Alexey Malygin & Galina Karpova
Pages: 357-369
Published online: 25 Feb 2019
AbstractforHydroxylation of Protein Constituents of the Human Translation System: Structural Aspects and Functional Assignments | Full Text | References | PDF (3.2 MB) | EPUB
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