Future Medicinal Chemistry, Volume 8, Issue 7 (2016)

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Future Medicinal Chemistry, Volume 8, Issue 7 (2016)

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Editorial

Editorial
Targeting Autophagy in Antitumor Agent Design: Furthering the ‘Lysosomal Love’ Strategy
Sumit Sahni, Zaklina Kovacevic, Danuta S Kalinowski, Michael Huang, Sharleen Menezes, Sukriti Krishan, Darius JR Lane, Patric J Jansson & Des R Richardson
Pages: 727-729
Published online: 05 May 2016
First Page PreviewforTargeting Autophagy in Antitumor Agent Design: Furthering the ‘Lysosomal Love’ Strategy | Full Text | References | PDF (820.6 KB)
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Research Article

Article
1,3-Diphenylpropan-1-Ones as Allosteric Modulators of α7 Nach Receptors with Analgesic and Antioxidant Properties
Manuel Criado, Beatriz Balsera, José Mulet, Salvador Sala, Francisco Sala, Roberto de la Torre-Martínez, Asia Fernández-Carvajal, Antonio Ferrer-Montiel, Silvia Moreno-Fernández, Marta Miguel, María Jesús Pérez de Vega & Rosario González-Muñiz
Pages: 731-749
Published online: 10 May 2016
Abstractfor1,3-Diphenylpropan-1-Ones as Allosteric Modulators of α7 Nach Receptors with Analgesic and Antioxidant Properties | Full Text | References | PDF (1.3 MB) | Supplemental
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Article
Study on 2-Arylthio-5-Iodo Pyrimidine Derivatives as Novel Nonnucleoside Inhibitors Against Hepatitis B Virus DNA Replication
Jianxiong Zhao, Jing Tu, Ningning Fan, Xiangmei Chen, Fengmin Lu, Yu Zhang, Liang Zhang, Chao Tian, Zhili Zhang, Junyi Liu & Xiaowei Wang
Pages: 751-763
Published online: 13 May 2016
AbstractforStudy on 2-Arylthio-5-Iodo Pyrimidine Derivatives as Novel Nonnucleoside Inhibitors Against Hepatitis B Virus DNA Replication | Full Text | References | PDF (1.7 MB)
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Review

Review Article
Progress in the Mechanism and Drug Development of Castration-Resistant Prostate Cancer
Minzan Zuo, Xi Xu, Tinghan Li, Raoling Ge & Zhiyu Li
Pages: 765-788
Published online: 05 May 2016
AbstractforProgress in the Mechanism and Drug Development of Castration-Resistant Prostate Cancer | Full Text | References | PDF (3.1 MB)
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Review Article
The Shifting Landscape of KAtp Channelopathies and the Need for ‘Sharper’ Therapeutics
Sujay V Kharade, Colin Nichols & Jerod S Denton
Pages: 789-802
Published online: 10 May 2016
AbstractforThe Shifting Landscape of KAtp Channelopathies and the Need for ‘Sharper’ Therapeutics | Full Text | References | PDF (3 MB)
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Review Article
Small-Molecule Approaches Toward the Targeting of Oncogenic Mirnas: Roadmap for the Discovery of Rna Modulators
Audrey Di Giorgio, Thi Phuong Anh Tran & Maria Duca
Pages: 803-816
Published online: 05 May 2016
AbstractforSmall-Molecule Approaches Toward the Targeting of Oncogenic Mirnas: Roadmap for the Discovery of Rna Modulators | Full Text | References | PDF (1.1 MB)
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Review Article
Store-Operated Crac Channel Inhibitors: Opportunities and Challenges
Chengsen Tian, Lupei Du, Yubin Zhou & Minyong Li
Pages: 817-832
Published online: 05 May 2016
AbstractforStore-Operated Crac Channel Inhibitors: Opportunities and Challenges | Full Text | References | PDF (1.5 MB)
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