Hemoglobin, Volume 32, Issue 1-2 (2008)

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Hemoglobin, Volume 32, Issue 1-2 (2008)

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PROCEEDINGS 16TH ICOC Limassol, Cyprus, October 2006

Article
Ethical Issues and Risk/Benefit Assessment of Iron Chelation Therapy: Advances with Deferiprone/Deferoxamine Combinations and Concerns about the Safety, Efficacy and Costs of Deferasirox
George J. Kontoghiorghes
Pages: 1-15
Published online: 07 Jul 2009
AbstractforEthical Issues and Risk/Benefit Assessment of Iron Chelation Therapy: Advances with Deferiprone/Deferoxamine Combinations and Concerns about the Safety, Efficacy and Costs of Deferasirox | Full Text | References | PDF (114.6 KB)
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Original

Article
Myocyte Damage and Loss of Myofibers is the Potential Mechanism of Iron Overload Toxicity in Congestive Cardiac Failure in Thalassemia. Complete Reversal of the Cardiomyopathy and Normalization of Iron Load by Deferiprone
Annita Kolnagou, Yiannis Michaelides, Christos Kontos, Kyriacos Kyriacou & George J. Kontoghiorghes
Pages: 17-28
Published online: 07 Jul 2009
AbstractforMyocyte Damage and Loss of Myofibers is the Potential Mechanism of Iron Overload Toxicity in Congestive Cardiac Failure in Thalassemia. Complete Reversal of the Cardiomyopathy and Normalization of Iron Load by Deferiprone | Full Text | References | PDF (564.3 KB)
  • 107 Views
  • 30 CrossRef citations
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Article
Effects of Combined Deferiprone and Deferoxamine Chelation Therapy on Iron Load Indices in β-Thalassemia
Maria Tsironi, George Assimakopoulos, Katerina Polonofi, Kalliopi Rigaki & Athanassios Aessopos
Pages: 29-34
Published online: 07 Jul 2009
AbstractforEffects of Combined Deferiprone and Deferoxamine Chelation Therapy on Iron Load Indices in β-Thalassemia | Full Text | References | PDF (69.4 KB)
  • 80 Views
  • 8 CrossRef citations
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Article
Immune and Neural Status of Thalassemic Patients Receiving Deferiprone or Combined Deferiprone and Deferoxamine Chelation Treatment
Natalie Tourkantoni, Miranda Athanassiou-Metaxa, Dimitrios Zafiriou, Vassiliki Tzimouli, Marina Economou, Antonia Taparkou, Vassilios Perifanis & Florendia Kanakoudi-Tsakalidou
Pages: 35-40
Published online: 07 Jul 2009
AbstractforImmune and Neural Status of Thalassemic Patients Receiving Deferiprone or Combined Deferiprone and Deferoxamine Chelation Treatment | Full Text | References | PDF (64.7 KB)
  • 76 Views
  • 3 CrossRef citations
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Article
Long Term Comparative Studies in Thalassemia Patients Treated with Deferoxamine or a Deferoxamine/Deferiprone Combination. Identification of Effective Chelation Therapy Protocols
Annita Kolnagou, Charalambos Economides, Eleni Eracleous & George J. Kontoghiorghes
Pages: 41-47
Published online: 07 Jul 2009
AbstractforLong Term Comparative Studies in Thalassemia Patients Treated with Deferoxamine or a Deferoxamine/Deferiprone Combination. Identification of Effective Chelation Therapy Protocols | Full Text | References | PDF (63.7 KB)
  • 108 Views
  • 45 CrossRef citations
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Article
Effects of Chelation Therapy on Cardiac Function Improvement in Thalassemia Patients: Literature Review and the Taiwanese Experience
Ching-Tien Peng, Chang-Hai Tsai & Kang-Hsi Wu
Pages: 49-62
Published online: 07 Jul 2009
AbstractforEffects of Chelation Therapy on Cardiac Function Improvement in Thalassemia Patients: Literature Review and the Taiwanese Experience | Full Text | References | PDF (2.2 MB)
  • 76 Views
  • 15 CrossRef citations
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Article
Congestive Heart Failure and Treatment in Thalassemia Major
Athanassios Aessopos, Maria Kati & Maria Tsironi
Pages: 63-73
Published online: 07 Jul 2009
AbstractforCongestive Heart Failure and Treatment in Thalassemia Major | Full Text | References | PDF (301.4 KB)
  • 153 Views
  • 9 CrossRef citations
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Article
The Uses and Differences of R2 and R2* in the Determination of Iron Overload in Iron Loaded Thalassemia Patients
Efstathios D. Gotsis
Pages: 75-83
Published online: 07 Jul 2009
AbstractforThe Uses and Differences of R2 and R2* in the Determination of Iron Overload in Iron Loaded Thalassemia Patients | Full Text | References | PDF (302.3 KB)
  • 65 Views
  • 4 CrossRef citations
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Article
Magnetic Resonance Imaging Assessment of Excess Iron in Thalassemia, Sickle Cell Disease and Other Iron Overload Diseases
John C. Wood & Nilesh Ghugre
Pages: 85-96
Published online: 07 Jul 2009
AbstractforMagnetic Resonance Imaging Assessment of Excess Iron in Thalassemia, Sickle Cell Disease and Other Iron Overload Diseases | Full Text | References | PDF (667.4 KB)
  • 371 Views
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Article
Standardized T2* Map of a Normal Human Heart to Correct T2* Segmental Artefacts; Myocardial Iron Overload and Fibrosis in Thalassemia Intermedia Versus Thalassemia Major Patients and Electrocardiogram Changes in Thalassemia Major Patients
Anna Ramazzotti, Alessia Pepe, Vincenzo Positano, Barbara Scattini, Maria F. Santarelli, Luigi Landini, Daniele De Marchi, Petra Keilberg, Giorgio Derchi, Francesco Formisano, Marcello Pili, Maria E. Lai, Gianluca Forni, Aldo Filosa, Luciano Prossomariti, Marcello Capra, Lorella Pitrolo, Caterina Borgna-Pignatti, Paolo Cianciulli, Aurelio Maggio & Massimo Lombardi
Pages: 97-107
Published online: 07 Jul 2009
AbstractforStandardized T2* Map of a Normal Human Heart to Correct T2* Segmental Artefacts; Myocardial Iron Overload and Fibrosis in Thalassemia Intermedia Versus Thalassemia Major Patients and Electrocardiogram Changes in Thalassemia Major Patients | Full Text | References | PDF (343.3 KB)
  • 93 Views
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Article
Insights on Regulation and Function of the Iron Regulatory Protein 1 (IRP1)
Jian Wang, Guohua Chen, Carine Filebeen & Kostas Pantopoulos
Pages: 109-115
Published online: 07 Jul 2009
AbstractforInsights on Regulation and Function of the Iron Regulatory Protein 1 (IRP1) | Full Text | References | PDF (615.8 KB)
  • 159 Views
  • 9 CrossRef citations
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Article
Iron Out-of-Balance: A Risk Factor for Acute and Chronic Diseases
Eugene D. Weinberg
Pages: 117-122
Published online: 07 Jul 2009
AbstractforIron Out-of-Balance: A Risk Factor for Acute and Chronic Diseases | Full Text | References | PDF (65.8 KB)
  • 133 Views
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Article
Can Iron Chelators Influence the Progression of Atherosclerosis?
Joannes J.M. Marx, Apriliana E.R. Kartikasari & Niki A. Georgiou
Pages: 123-134
Published online: 07 Jul 2009
AbstractforCan Iron Chelators Influence the Progression of Atherosclerosis? | Full Text | References | PDF (281.9 KB)
  • 126 Views
  • 11 CrossRef citations
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Article
The Role of Zinc, Copper and Iron in the Pathogenesis of Diabetes and Diabetic Complications: Therapeutic Effects by Chelators
Yang Zheng, Xiao-Kun Li, Yuehui Wang & Lu Cai
Pages: 135-145
Published online: 07 Jul 2009
AbstractforThe Role of Zinc, Copper and Iron in the Pathogenesis of Diabetes and Diabetic Complications: Therapeutic Effects by Chelators | Full Text | References | PDF (214.7 KB)
  • 858 Views
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Article
A New Approach for Potential Combined Chelation Therapy Using Mono- and Bis-Hydroxypyridinones
M. Amélia Santos, Sofia Gama, Marco Gil & Lurdes Gano
Pages: 147-156
Published online: 07 Jul 2009
AbstractforA New Approach for Potential Combined Chelation Therapy Using Mono- and Bis-Hydroxypyridinones | Full Text | References | PDF (222.8 KB)
  • 99 Views
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Article
Variable Inhibitory Effects on the Formation of Dinitrosyl Iron Complexes by Deferoxamine and Salicylaldehyde Isonicotinoyl Hydrazone in K562 Cells
Sylwia Meczynska, Hanna Lewandowska, Barbara Sochanowicz, Jaroslaw Sadlo & Marcin Kruszewski
Pages: 157-163
Published online: 07 Jul 2009
AbstractforVariable Inhibitory Effects on the Formation of Dinitrosyl Iron Complexes by Deferoxamine and Salicylaldehyde Isonicotinoyl Hydrazone in K562 Cells | Full Text | References | PDF (279.8 KB)
  • 71 Views
  • 13 CrossRef citations
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Article
Iron Chelators and Free Radical Scavengers in Naturally Occurring Polyhydroxylated 1,4-Naphthoquinones
Alexander V. Lebedev, Marina V. Ivanova & Dmitri O. Levitsky
Pages: 165-179
Published online: 07 Jul 2009
AbstractforIron Chelators and Free Radical Scavengers in Naturally Occurring Polyhydroxylated 1,4-Naphthoquinones | Full Text | References | PDF (537.6 KB)
  • 116 Views
  • 38 CrossRef citations
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Article
Therapeutic Effects of an Oral Chelator Targeting Skeletal Tissue Damage in Experimental Postmenopausal Osteoporosis in Rats
Gang Liu, Ping Men, Gerry H. Kenner & Scott C. Miller
Pages: 181-190
Published online: 07 Jul 2009
AbstractforTherapeutic Effects of an Oral Chelator Targeting Skeletal Tissue Damage in Experimental Postmenopausal Osteoporosis in Rats | Full Text | References | PDF (169.3 KB)
  • 96 Views
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Article
The Effects of Bicarbonate and its Combination with Chelating Agents Used for the Removal of Depleted Uranium in Rats
Satoshi Fukuda, Mizuyo Ikeda, Mariko Nakamura, Akira Katoh, Xueming Yan, Yuyuan Xie & George J. Kontoghiorghes
Pages: 191-198
Published online: 07 Jul 2009
AbstractforThe Effects of Bicarbonate and its Combination with Chelating Agents Used for the Removal of Depleted Uranium in Rats | Full Text | References | PDF (216.9 KB)
  • 66 Views
  • 17 CrossRef citations
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Article
Diethylene-Triamine-Penta-Acetate Administration Protocol for Radiological Emergency Medicine in Nuclear Fuel Reprocessing Plants
Yutaka Jin
Pages: 199-206
Published online: 07 Jul 2009
AbstractforDiethylene-Triamine-Penta-Acetate Administration Protocol for Radiological Emergency Medicine in Nuclear Fuel Reprocessing Plants | Full Text | References | PDF (562.7 KB)
  • 22 Views
  • 0 CrossRef citations
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Article
Pyridoxal Isonicotinoyl Hydrazone (PIH) and its Analogs as Protectants Against Anthracycline-Induced Cardiotoxicity
Tomas Simunek, Martin Sterba, Olga Popelova, Helena Kaiserova, Anna Potacova, Michaela Adamcova, Yvona Mazurova, Premysl Ponka & Vladimir Gersl
Pages: 207-215
Published online: 07 Jul 2009
AbstractforPyridoxal Isonicotinoyl Hydrazone (PIH) and its Analogs as Protectants Against Anthracycline-Induced Cardiotoxicity | Full Text | References | PDF (183.9 KB)
  • 67 Views
  • 7 CrossRef citations
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Article
Chelators Controlling Metal Metabolism and Toxicity Pathways: Applications in Cancer Prevention, Diagnosis and Treatment
George J. Kontoghiorghes, Aglaia Efstathiou, Stella Ioannou-Loucaides & Annita Kolnagou
Pages: 217-227
Published online: 07 Jul 2009
AbstractforChelators Controlling Metal Metabolism and Toxicity Pathways: Applications in Cancer Prevention, Diagnosis and Treatment | Full Text | References | PDF (287.2 KB)
  • 303 Views
  • 29 CrossRef citations
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Original Article

Article
Pharmacogenomics and Therapeutics of Hemoglobinopathies
George P. Patrinos & Frank G. Grosveld
Pages: 229-236
Published online: 07 Jul 2009
AbstractforPharmacogenomics and Therapeutics of Hemoglobinopathies | Full Text | References | PDF (69.5 KB)
  • 171 Views
  • 25 CrossRef citations
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