Leukemia & Lymphoma, Volume 53, Issue 11 (2012)

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Leukemia & Lymphoma, Volume 53, Issue 11 (2012)

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Commentaries on selected articles in this issue

Article Commentary
Interfering with CD40 ligation: a sensitive matter in chronic lymphocytic leukemia
Alessandra Ferrajoli
Pages: 2093-2094
Published online: 21 May 2012
CitationforInterfering with CD40 ligation: a sensitive matter in chronic lymphocytic leukemia | Full Text | References | PDF (129.8 KB) | Supplemental
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Commentary

Article Commentary
Interim response assessment for Hodgkin lymphoma: size matters
Rebecca L. Elstrom
Pages: 2095-2096
Published online: 09 Jul 2012
CitationforInterim response assessment for Hodgkin lymphoma: size matters | Full Text | References | PDF (128.2 KB) | Supplemental
  • 510 Views
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Article Commentary
Back to basics: the complete blood cell count adds to the ability of immunohistochemistry in diffuse large B-cell lymphoma prognosis
Frank Vari & Maher K. Gandhi
Pages: 2097-2098
Published online: 09 Jul 2012
CitationforBack to basics: the complete blood cell count adds to the ability of immunohistochemistry in diffuse large B-cell lymphoma prognosis | Full Text | References | PDF (130 KB) | Supplemental
  • 575 Views
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Article Commentary
Does arsenic trioxide impact fertility?
Eytan M. Stein & Martin S. Tallman
Pages: 2099-2100
Published online: 21 May 2012
CitationforDoes arsenic trioxide impact fertility? | Full Text | References | PDF (126.2 KB) | Supplemental
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Article Commentary
Improving treatment for chronic lymphocytic leukemia by rational use of monoclonal antibodies
Mikołaj Słabicki & Thorsten Zenz
Pages: 2101-2102
Published online: 03 Sep 2012
CitationforImproving treatment for chronic lymphocytic leukemia by rational use of monoclonal antibodies | Full Text | References | PDF (136.8 KB) | Supplemental
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Article Commentary
Lymphoma-associated versus lymphocytic-variant hypereosinophilia
Anita D'Souza, Animesh Pardanani & Ayalew Tefferi
Pages: 2103-2104
Published online: 13 Aug 2012
CitationforLymphoma-associated versus lymphocytic-variant hypereosinophilia | Full Text | References | PDF (131.7 KB) | Supplemental
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Reviews

Review Article
Diagnostic techniques and therapeutic challenges in patients with TP53 dysfunctional chronic lymphocytic leukemia
Giles Best, Philip Thompson & Constantine S. Tam
Pages: 2105-2115
Published online: 31 May 2012
AbstractforDiagnostic techniques and therapeutic challenges in patients with TP53 dysfunctional chronic lymphocytic leukemia | Full Text | References | PDF (381.5 KB) | Supplemental
  • 316 Views
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Review Article

Review Article
Role of p53 family members p73 and p63 in human hematological malignancies
Evguenia M. Alexandrova & Ute M. Moll
Pages: 2116-2129
Published online: 21 May 2012
AbstractforRole of p53 family members p73 and p63 in human hematological malignancies | Full Text | References | PDF (310 KB) | Supplemental
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Review Article
Apoptotic cells in allogeneic hematopoietic stem cell transplantations: “turning trash into gold”
Ilias Pessach, Avichai Shimoni & Arnon Nagler
Pages: 2130-2135
Published online: 04 May 2012
AbstractforApoptotic cells in allogeneic hematopoietic stem cell transplantations: “turning trash into gold” | Full Text | References | PDF (221.7 KB) | Supplemental
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Original Articles: Clinical

Article
Phase I study of the anti-CD40 humanized monoclonal antibody lucatumumab (HCD122) in relapsed chronic lymphocytic leukemia
John C. Byrd, Thomas J. Kipps, Ian W. Flinn, Maureen Cooper, Olatoyosi Odenike, Jennifer Bendiske, John Rediske, Sanela Bilic, Jyotirmoy Dey, Johan Baeck & Susan O’Brien
Pages: 2136-2142
Published online: 12 Jun 2012
AbstractforPhase I study of the anti-CD40 humanized monoclonal antibody lucatumumab (HCD122) in relapsed chronic lymphocytic leukemia | Full Text | References | PDF (185.9 KB) | Supplemental
  • 629 Views
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Research Article

Article
Interim [18F]fluorodeoxyglucose positron emission tomography imaging in stage I–II non-bulky Hodgkin lymphoma: would using combined positron emission tomography and computed tomography criteria better predict response than each test alone?
Lale Kostakoglu, Heiko Schöder, Jeffrey L. Johnson, Nathan C. Hall, Lawrence H. Schwartz, David J. Straus, Ann S. LaCasce, Sin-Ho Jung, Nancy L. Bartlett, George P. Canellos, Bruce D. Cheson & For the Leukemia Group B
Pages: 2143-2150
Published online: 28 Aug 2012
AbstractforInterim [18F]fluorodeoxyglucose positron emission tomography imaging in stage I–II non-bulky Hodgkin lymphoma: would using combined positron emission tomography and computed tomography criteria better predict response than each test alone? | Full Text | References | PDF (300.2 KB) | Supplemental
  • 587 Views
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Article
Effects of erythropoiesis-stimulating agents on survival and other outcomes in patients with lymphoproliferative malignancies: a study-level meta-analysis
Michael Hedenus, Anders Österborg, Dianne Tomita, Chet Bohac & Bertrand Coiffier
Pages: 2151-2158
Published online: 22 May 2012
AbstractforEffects of erythropoiesis-stimulating agents on survival and other outcomes in patients with lymphoproliferative malignancies: a study-level meta-analysis | Full Text | References | PDF (370.3 KB) | Supplemental
  • 1059 Views
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Open Access
Article
Absolute monocyte/lymphocyte count prognostic score is independent of immunohistochemically determined cell of origin in predicting survival in diffuse large B-cell lymphoma
Luis F. Porrata, Kay Ristow, Thomas M. Habermann, Nazan Ozsan, Ahmet Dogan, William Macon, Joseph P. Colgan, Thomas E. Witzig, David J. Inwards, Stephen M. Ansell, Ivana N. Micallef, Patrick B. Johnston, Grzegorz S. Nowakowski, Carrie Thompson & Svetomir N. Markovic
Pages: 2159-2165
Published online: 21 May 2012
AbstractforAbsolute monocyte/lymphocyte count prognostic score is independent of immunohistochemically determined cell of origin in predicting survival in diffuse large B-cell lymphoma | Full Text | References | PDF (386.1 KB) | Supplemental
  • 411 Views
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Article
The Gordian knot of interim 18-fluorodeoxyglucose positron emission tomography for Hodgkin lymphoma: a meta-analysis and commentary on published studies
Panayiotis D. Ziakas, Loukia S. Poulou, Michael Voulgarelis & Loukas Thanos
Pages: 2166-2174
Published online: 22 May 2012
AbstractforThe Gordian knot of interim 18-fluorodeoxyglucose positron emission tomography for Hodgkin lymphoma: a meta-analysis and commentary on published studies | Full Text | References | PDF (382.4 KB) | Supplemental
  • 221 Views
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Article
Rituximab in treatment of primary gastric diffuse large B-cell lymphoma
Jian Zhang, Gang Li, Haiyan Yang, Xiaojian Liu & Junning Cao
Pages: 2175-2181
Published online: 19 Apr 2012
AbstractforRituximab in treatment of primary gastric diffuse large B-cell lymphoma | Full Text | References | PDF (315.3 KB) | Supplemental
  • 281 Views
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Article
P53 deletion is independently associated with increased age and decreased survival in a cohort of Chinese patients with diffuse large B-cell lymphoma
Zhuxia Jia, Jinyuan He, Ling Cen, Wenmin Han, Naike Jiang, Jianhe Yang & Min Zhou
Pages: 2182-2185
Published online: 21 May 2012
AbstractforP53 deletion is independently associated with increased age and decreased survival in a cohort of Chinese patients with diffuse large B-cell lymphoma | Full Text | References | PDF (212.2 KB) | Supplemental
  • 153 Views
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Article
Combination of cytarabine and topotecan in patients treated for acute myeloid leukemia with persistent disease after frontline induction
Thomas Prébet, Estelle Jean, Aurélie Autret, Aude Charbonnier, Jerome Rey, Anne Etienne, Evelyne D'incan, Sabine Fürst, Christine Arnoulet, Didier Blaise & Norbert Vey
Pages: 2186-2191
Published online: 07 Aug 2012
AbstractforCombination of cytarabine and topotecan in patients treated for acute myeloid leukemia with persistent disease after frontline induction | Full Text | References | PDF (198.2 KB) | Supplemental
  • 303 Views
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Article
Parenthood in patients with acute promyelocytic leukemia after treatment with arsenic trioxide: a case series
Shilpa Gupta, Bhausaheb Bagel, Sumeet Gujral, P. G. Subramanian, Navin Khattry, Hari Menon & Reena Nair
Pages: 2192-2194
Published online: 30 Apr 2012
AbstractforParenthood in patients with acute promyelocytic leukemia after treatment with arsenic trioxide: a case series | Full Text | References | PDF (146.2 KB) | Supplemental
  • 460 Views
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Article
WT1 mutations and single nucleotide polymorphism rs16754 analysis of patients with pediatric acute myeloid leukemia in a Chinese population
Xi Chen, Yongchen Yang, Yi Huang, Junjie Tan, Yuanyuan Chen, Jing Yang, Hu Dou, Lin Zou, Jie Yu & Liming Bao
Pages: 2195-2204
Published online: 21 May 2012
AbstractforWT1 mutations and single nucleotide polymorphism rs16754 analysis of patients with pediatric acute myeloid leukemia in a Chinese population | Full Text | References | PDF (279.4 KB) | Supplemental
  • 285 Views
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Article
Immunohistological diagnosis of plasma cell myeloma based on cytoplasmic kappa/lambda ratio of CD138-positive plasma cells
Shoko Nakayama-Ichiyama, Taiji Yokote, Yuji Hirata, Kazuki Iwaki, Toshikazu Akioka, Takuji Miyoshi, Ayami Takayama, Uta Nishiwaki, Yuki Masuda, Yasuichiro Nishimura, Motomu Tsuji & Toshiaki Hanafusa
Pages: 2205-2209
Published online: 21 May 2012
AbstractforImmunohistological diagnosis of plasma cell myeloma based on cytoplasmic kappa/lambda ratio of CD138-positive plasma cells | Full Text | References | PDF (394.2 KB) | Supplemental
  • 514 Views
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Article
JAK2V617F allele burden is associated with transformation to myelofibrosis
Maya Koren-Michowitz, Joseph Landman, Yoram Cohen, Naomi Rahimi-Levene, Ophira Salomon, Maria Michael, Ninette Amariglio & Arnon Nagler
Pages: 2210-2213
Published online: 21 May 2012
AbstractforJAK2V617F allele burden is associated with transformation to myelofibrosis | Full Text | References | PDF (179.6 KB) | Supplemental
  • 332 Views
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Article
Nucleophosmin gene-based monitoring in de novo cytogenetically normal acute myeloid leukemia with nucleophosmin gene mutations: comparison with cytofluorimetric analysis and study of Wilms tumor gene 1 expression
Maurizio Miglino, Nicoletta Colombo, Raffaella Grasso, Carlo Marani, Marino Clavio, Gian Matteo Pica, Filippo Ballerini, Chiara Ghiggi, Paola Minetto, Fabio Guolo, Angelo Michele Carella & Marco Gobbi
Pages: 2214-2217
Published online: 21 May 2012
AbstractforNucleophosmin gene-based monitoring in de novo cytogenetically normal acute myeloid leukemia with nucleophosmin gene mutations: comparison with cytofluorimetric analysis and study of Wilms tumor gene 1 expression | Full Text | References | PDF (197.7 KB) | Supplemental
  • 317 Views
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Original Articles: Research

Article
Complement dependent cytotoxicity in chronic lymphocytic leukemia: ofatumumab enhances alemtuzumab complement dependent cytotoxicity and reveals cells resistant to activated complement
Nisar A. Baig, Ronald P. Taylor, Margaret A. Lindorfer, Amy K. Church, Betsy R. Laplant, Emily S. Pavey, Grzegorz S. Nowakowski & Clive S. Zent
Pages: 2218-2227
Published online: 21 May 2012
AbstractforComplement dependent cytotoxicity in chronic lymphocytic leukemia: ofatumumab enhances alemtuzumab complement dependent cytotoxicity and reveals cells resistant to activated complement | Full Text | References | PDF (398.5 KB) | Supplemental
  • 632 Views
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Research Article

Article
Leukemia among male construction workers in California, 1988–2007
Sara E. Luckhaupt, Dennis Deapen, Rosemary Cress, Pam Schumacher, Rui Shen & Geoffrey M. Calvert
Pages: 2228-2236
Published online: 21 May 2012
AbstractforLeukemia among male construction workers in California, 1988–2007 | Full Text | References | PDF (196.1 KB) | Supplemental
  • 218 Views
  • 6 CrossRef citations
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Article
Biological effects of decreasing RBM15 on chronic myelogenous leukemia cells
Yuxia Yang, Saifeng Wang, Yanju Zhang & Xiaoling Zhu
Pages: 2237-2244
Published online: 12 Apr 2012
AbstractforBiological effects of decreasing RBM15 on chronic myelogenous leukemia cells | Full Text | References | PDF (620 KB) | Supplemental
  • 390 Views
  • 18 CrossRef citations
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Article
MDM2 SNP309 variation contributes to leukemia risk: meta-analyses based on 7259 subjects
Wenlei Zhuo, Liang Zhang, Junjun Ling, Bo Zhu & Zhengtang Chen
Pages: 2245-2252
Published online: 12 Jun 2012
AbstractforMDM2 SNP309 variation contributes to leukemia risk: meta-analyses based on 7259 subjects | Full Text | References | PDF (447.1 KB) | Supplemental
  • 169 Views
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Article
Rapamycin enhances dimethyl sulfoxide-mediated growth arrest in human myelogenous leukemia cells
Hrvoje Lalic, Vesna Lukinovic-Skudar, Hrvoje Banfic & Dora Visnjic
Pages: 2253-2261
Published online: 21 May 2012
AbstractforRapamycin enhances dimethyl sulfoxide-mediated growth arrest in human myelogenous leukemia cells | Full Text | References | PDF (531.8 KB) | Supplemental
  • 278 Views
  • 6 CrossRef citations
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Article
Cytosine arabinoside potentiates the apoptotic effect of bendamustine on several B- and T-cell leukemia/lymphoma cells and cell lines
Silvia Castegnaro, Carlo Visco, Katia Chieregato, Martina Bernardi, Elena Albiero, Cristina Zanon, Domenico Madeo & Francesco Rodeghiero
Pages: 2262-2268
Published online: 21 May 2012
AbstractforCytosine arabinoside potentiates the apoptotic effect of bendamustine on several B- and T-cell leukemia/lymphoma cells and cell lines | Full Text | References | PDF (399.1 KB) | Supplemental
  • 428 Views
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Article
Establishment and characterization of therapy-resistant mantle cell lymphoma cell lines derived from diff erent tissue sites
Adam K. Ahrens, Nagendra K. Chaturvedi, Tara M. Nordgren, Bhavana J. Dave & Shantaram S. Joshi
Pages: 2269-2278
Published online: 13 Jun 2012
AbstractforEstablishment and characterization of therapy-resistant mantle cell lymphoma cell lines derived from diff erent tissue sites | Full Text | References | PDF (519.1 KB) | Supplemental
  • 301 Views
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Letters to the Editor

Letter
A case of systemic anaplastic lymphoma kinase-negative anaplastic large cell lymphoma associated with hypereosinophilia, granulomatous myositis and vasculitis
Penelope A. McKelvie, Shereen Oon, Evange Romas, Harshal Nandurkar & Constantine S. Tam
Pages: 2279-2282
Published online: 21 May 2012
First Page PreviewforA case of systemic anaplastic lymphoma kinase-negative anaplastic large cell lymphoma associated with hypereosinophilia, granulomatous myositis and vasculitis | Full Text | References | PDF (325.5 KB) | Supplemental
  • 248 Views
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Letter

Letter
Progressive multifocal leukoencephalopathy in a patient with Hodgkin lymphoma treated with brentuximab vedotin
Nina D. Wagner-Johnston, Nancy L. Bartlett, Amanda Cashen & Joseph R. Berger
Pages: 2283-2286
Published online: 23 Apr 2012
First Page PreviewforProgressive multifocal leukoencephalopathy in a patient with Hodgkin lymphoma treated with brentuximab vedotin | Full Text | References | PDF (215.1 KB) | Supplemental
  • 467 Views
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Letter
Refractory anemia with ring sideroblasts associated with marked thrombocytosis harboring cytogenetic abnormality dup(2)(p15p22) treated with decitabine
Juwon Kim, Yu Ri Kim & Kyung-A Lee
Pages: 2287-2289
Published online: 16 May 2012
First Page PreviewforRefractory anemia with ring sideroblasts associated with marked thrombocytosis harboring cytogenetic abnormality dup(2)(p15p22) treated with decitabine | Full Text | References | PDF (192.1 KB) | Supplemental
  • 162 Views
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Letter
Rituximab and bendamustine in patients with CD20+ diffuse large B-cell lymphoma not eligible for cyclophosphamide, doxorubicin, vincristine and prednisone-like chemotherapy
Eva Walter, Thomas Schmitt,Sascha Dietrich, Anthony Ho & Mathias Witzens-Harig
Pages: 2290-2292
Published online: 22 May 2012
First Page PreviewforRituximab and bendamustine in patients with CD20+ diffuse large B-cell lymphoma not eligible for cyclophosphamide, doxorubicin, vincristine and prednisone-like chemotherapy | Full Text | References | PDF (139.2 KB) | Supplemental
  • 1030 Views
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Letter
Identification of amylase-binding monoclonal immunoglobulins in multiple myeloma associated with macroamylasemia
Tetsuo Machida, Reiko Shizuka, Shigeki Yabe, Yoshino Kobayashi, Sachie Yomoda, Mamoru Sawamura & Masami Murakami
Pages: 2293-2295
Published online: 30 Apr 2012
First Page PreviewforIdentification of amylase-binding monoclonal immunoglobulins in multiple myeloma associated with macroamylasemia | Full Text | References | PDF (145 KB) | Supplemental
  • 167 Views
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Letter
An acquired factor VIII inhibitor in a myeloproliferative neoplasm presenting with severe retroperitoneal hemorrhage
Claudia Vener, Andrea Artoni, Carla Boschetti, Nicola Stefano Fracchiolla, Umberto Gianelli, Agostino Cortelezzi & Alessandra Iurlo
Pages: 2296-2298
Published online: 07 Aug 2012
First Page PreviewforAn acquired factor VIII inhibitor in a myeloproliferative neoplasm presenting with severe retroperitoneal hemorrhage | Full Text | References | PDF (239.6 KB) | Supplemental
  • 79 Views
  • 2 CrossRef citations
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Letter
Rituximab-induced coagulopathy
Jan Novak, Heidi Mocikova, Petr Pavlicek, Lubica Gaherova & Tomas Kozak
Pages: 2299-2301
Published online: 16 May 2012
First Page PreviewforRituximab-induced coagulopathy | Full Text | References | PDF (137.8 KB) | Supplemental
  • 179 Views
  • 3 CrossRef citations
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Letter
Richter transformation of chronic lymphocytic leukemia into composite diffuse large B-cell and Hodgkin lymphoma
Fotios V. Michelis, Georgia Kourti, Maria Skertsou, Themistokles Karmiris, Dimitra P. Rontogianni & Nikolaos Harhalakis
Pages: 2302-2303
Published online: 23 Apr 2012
CitationforRichter transformation of chronic lymphocytic leukemia into composite diffuse large B-cell and Hodgkin lymphoma | Full Text | References | PDF (237 KB) | Supplemental
  • 292 Views
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Letter
Chronic lymphocytic leukemia associated leukemia cutis presenting as acne rosacea
Elise Ng, Vishal Patel, Danielle Engler & Marc Grossman
Pages: 2304-2306
Published online: 23 Apr 2012
First Page PreviewforChronic lymphocytic leukemia associated leukemia cutis presenting as acne rosacea | Full Text | References | PDF (318.8 KB) | Supplemental
  • 132 Views
  • 3 CrossRef citations
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Letter
Successful reduced-intensity umbilical cord blood transplant for fulminant hemophagocytic syndrome in an adult with pre-existing rheumatoid arthritis and autoimmune hemolytic anemia
Hidekazu Itamura, Noriyasu Fukushima, Seiji Kondo, Chisako Urata, Mariko Tanaka-Yoshimura, Masako Yokoo, Masaru Ide, Takashi Hisatomi, Yasushi Kubota, Eisaburo Sueoka, Tatsuo Ichinohe & Shinya Kimura
Pages: 2307-2309
Published online: 19 Apr 2012
First Page PreviewforSuccessful reduced-intensity umbilical cord blood transplant for fulminant hemophagocytic syndrome in an adult with pre-existing rheumatoid arthritis and autoimmune hemolytic anemia | Full Text | References | PDF (177.2 KB) | Supplemental
  • 119 Views
  • 2 CrossRef citations
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Letter
Imatinib-induced aplastic anemia in a patient with chronic myeloid leukemia
Mohamed Mabed, Ashraf M. Elhefni & Ghazi Damnhouri
Pages: 2310-2311
Published online: 30 Apr 2012
CitationforImatinib-induced aplastic anemia in a patient with chronic myeloid leukemia | Full Text | References | PDF (135.4 KB) | Supplemental
  • 237 Views
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CLL Young Investigators' Meeting 2011

Article
Highlights of the 6th Young Investigators’ Meeting on chronic lymphocytic leukemia
Arnon P. Kater, Tait Shanafelt, Kirsten Fischer & William Wierda
Pages: 2312-2313
Published online: 28 Aug 2012
CitationforHighlights of the 6th Young Investigators’ Meeting on chronic lymphocytic leukemia | Full Text | PDF (566.4 KB) | Supplemental
  • 117 Views
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Research Article

Article
Heat shock protein-90 inhibitor, NVP-AUY922, is effective in combination with fludarabine against chronic lymphocytic leukemia cells cultured on CD40L-stromal layer and inhibits their activated/proliferative phenotype
O. Giles Best & Stephen P. Mulligan
Pages: 2314-2320
Published online: 09 Jul 2012
AbstractforHeat shock protein-90 inhibitor, NVP-AUY922, is effective in combination with fludarabine against chronic lymphocytic leukemia cells cultured on CD40L-stromal layer and inhibits their activated/proliferative phenotype | Full Text | References | PDF (337.8 KB) | Supplemental
  • 327 Views
  • 10 CrossRef citations
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Article
Chronic lymphocytic leukemia specific T-cell subset alterations are clone-size dependent and not present in monoclonal B lymphocytosis
G. Doreen te Raa, Sanne H. Tonino, Ester B. M. Remmerswaal, Arend Jan van Houte, Harry R. Koene, Marinus H. van Oers & Arnon P. Kater
Pages: 2321-2325
Published online: 25 Aug 2012
AbstractforChronic lymphocytic leukemia specific T-cell subset alterations are clone-size dependent and not present in monoclonal B lymphocytosis | Full Text | References | PDF (234.6 KB) | Supplemental
  • 281 Views
  • 10 CrossRef citations
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Article
Chronic lymphocytic leukemia in African Americans
Catherine C. Coombs, Lorenzo Falchi, J. Brice Weinberg, Alessandra Ferrajoli & Mark C. Lanasa
Pages: 2326-2329
Published online: 09 Jul 2012
AbstractforChronic lymphocytic leukemia in African Americans | Full Text | References | PDF (269.1 KB) | Supplemental
  • 359 Views
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