Leukemia & Lymphoma, Volume 53, Issue 12 (2012)

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Leukemia & Lymphoma, Volume 53, Issue 12 (2012)

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Commentaries on selected articles in this issue

Article Commentary
Maintenance rituximab revisited: is it worth the cost?
Sonali M. Smith
Pages: 2331-2332
Published online: 09 Jul 2012
CitationforMaintenance rituximab revisited: is it worth the cost? | Full Text | References | PDF (132.9 KB) | Supplemental
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Commentary

Article Commentary
Advancing therapeutics in human immunodeficiency virus-associated lymphoma: where to go from here?
Kieron Dunleavy
Pages: 2333-2334
Published online: 17 Aug 2012
CitationforAdvancing therapeutics in human immunodeficiency virus-associated lymphoma: where to go from here? | Full Text | References | PDF (134.9 KB) | Supplemental
  • 391 Views
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Article Commentary
Total ambulatory hemato-oncological care: a myth or reality?
Chezi Ganzel & Jacob M. Rowe
Pages: 2335-2336
Published online: 09 Jul 2012
CitationforTotal ambulatory hemato-oncological care: a myth or reality? | Full Text | References | PDF (126.1 KB) | Supplemental
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Article Commentary
Activation of hypoxia signaling is marker of poor prognosis in myelodysplasia
Harold Elias & Amit Verma
Pages: 2337-2338
Published online: 17 Aug 2012
CitationforActivation of hypoxia signaling is marker of poor prognosis in myelodysplasia | Full Text | References | PDF (128.4 KB) | Supplemental
  • 501 Views
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Article Commentary
The BRAF-V600E mutation in hematological malignancies: a new player in hairy cell leukemia and Langerhans cell histiocytosis
Tamar Tadmor, Enrico Tiacci, Brunangelo Falini & Aaron Polliack
Pages: 2339-2340
Published online: 13 Aug 2012
CitationforThe BRAF-V600E mutation in hematological malignancies: a new player in hairy cell leukemia and Langerhans cell histiocytosis | Full Text | References | PDF (136.3 KB) | Supplemental
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Reviews

Review Article
Diagnosis and management of rare gastrointestinal lymphomas
Eliza A. Hawkes, Andrew Wotherspoon & David Cunningham
Pages: 2341-2350
Published online: 21 Jun 2012
AbstractforDiagnosis and management of rare gastrointestinal lymphomas | Full Text | References | PDF (356.2 KB) | Supplemental
  • 889 Views
  • 17 CrossRef citations
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Review Article

Review Article
Off-target effects of BCR–ABL1 inhibitors and their potential long-term implications in patients with chronic myeloid leukemia
Juan Luis Steegmann, Francisco Cervantes, Philipp le Coutre, Kimmo Porkka & Giuseppe Saglio
Pages: 2351-2361
Published online: 18 Jun 2012
AbstractforOff-target effects of BCR–ABL1 inhibitors and their potential long-term implications in patients with chronic myeloid leukemia | Full Text | References | PDF (269.3 KB) | Supplemental
  • 1746 Views
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Review Article
Targeting the B cell receptor pathway in chronic lymphocytic leukemia
Matthew S. Davids & Jennifer R. Brown
Pages: 2362-2370
Published online: 23 May 2012
AbstractforTargeting the B cell receptor pathway in chronic lymphocytic leukemia | Full Text | References | PDF (243.4 KB) | Supplemental
  • 1346 Views
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Original Articles: Clinical

Article
Cost-effectiveness of rituximab as maintenance therapy in patients with follicular non-Hodgkin lymphoma after responding to first-line rituximab plus chemotherapy
John Hornberger, Rebecca Chien, Mark Friedmann, Leona Han, Ashwini Shewade, Sacha Satram-Hoang & Carolina Reyes
Pages: 2371-2377
Published online: 12 Jun 2012
AbstractforCost-effectiveness of rituximab as maintenance therapy in patients with follicular non-Hodgkin lymphoma after responding to first-line rituximab plus chemotherapy | Full Text | References | PDF (342.2 KB) | Supplemental
  • 797 Views
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Research Article

Article
Prognosis in primary effusion lymphoma is associated with the number of body cavities involved
Jorge J. Castillo, Helen Shum, Majid Lahijani, Eric S. Winer & James N. Butera
Pages: 2378-2382
Published online: 13 Jun 2012
AbstractforPrognosis in primary effusion lymphoma is associated with the number of body cavities involved | Full Text | References | PDF (228.6 KB) | Supplemental
  • 304 Views
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Article
Outcome of patients with relapsed/refractory acquired immune deficiency syndrome-related lymphoma diagnosed 1999–2008 and treated with curative intent in the AIDS Malignancy Consortium
Ulas D. Bayraktar, Juan Carlos Ramos, Adam Petrich, Neel Gupta, Shelly Lensing, P. C. Moore, Erin G. Reid, David M. Aboulafia, Lee Ratner, Ronald Mitsuyasu, Timothy Cooley, David H. Henry, Paul Barr & Ariela Noy
Pages: 2383-2389
Published online: 09 Jul 2012
AbstractforOutcome of patients with relapsed/refractory acquired immune deficiency syndrome-related lymphoma diagnosed 1999–2008 and treated with curative intent in the AIDS Malignancy Consortium | Full Text | References | PDF (208.6 KB) | Supplemental
  • 249 Views
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Article
Incidence, predictors and significance of severe toxicity in patients with human immunodeficiency virus-associated Hodgkin lymphoma
Hatoon M. Ezzat, Matthew C. Cheung, Lisa K. Hicks, Jordana Boro, Julio S. G. Montaner, Viviane Dias Lima, Marianne Harris & Heather A. Leitch
Pages: 2390-2396
Published online: 18 Jun 2012
AbstractforIncidence, predictors and significance of severe toxicity in patients with human immunodeficiency virus-associated Hodgkin lymphoma | Full Text | References | PDF (186.6 KB) | Supplemental
  • 364 Views
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Article
Hotel-based ambulatory care for complex cancer patients: a review of the University College London Hospital experience
Jonathan Sive, Kirit M. Ardeshna, Simon Cheesman, Franel le Grange, Stephen Morris, Claire Nicholas, Karl Peggs, Paula Statham & Anthony H. Goldstone
Pages: 2397-2404
Published online: 13 Jun 2012
AbstractforHotel-based ambulatory care for complex cancer patients: a review of the University College London Hospital experience | Full Text | References | PDF (246.5 KB) | Supplemental
  • 530 Views
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Article
Neuroleukemiosis: an unusual cause of peripheral neuropathy
Chandan G. Reddy, Michelle L. Mauermann, Benjamin M. Solomon, Michael D. Ringler, Nivedita U. Jerath, Kebede H. Begna, Kimberly K. Amrami & Robert J. Spinner
Pages: 2405-2411
Published online: 28 May 2012
AbstractforNeuroleukemiosis: an unusual cause of peripheral neuropathy | Full Text | References | PDF (334.1 KB) | Supplemental
  • 733 Views
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Article
Hypoxia-inducible factor-1α expression indicates poor prognosis in myelodysplastic syndromes
Hongyan Tong, Chao Hu, Zhengping Zhuang, Lijun Wang & Jie Jin
Pages: 2412-2418
Published online: 18 Jun 2012
AbstractforHypoxia-inducible factor-1α expression indicates poor prognosis in myelodysplastic syndromes | Full Text | References | PDF (328.8 KB) | Supplemental
  • 485 Views
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Article
Childhood leukemia and its impact on graduation and having children: results from a national survey
Anne Zynda, Simone Reinmuth, Constanze Pfitzer, Cynthia Hohmann, Thomas Keil & Anja Borgmann-Staudt
Pages: 2419-2422
Published online: 05 Jun 2012
AbstractforChildhood leukemia and its impact on graduation and having children: results from a national survey | Full Text | References | PDF (205 KB) | Supplemental
  • 298 Views
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Article
Potential application of IDH1 and IDH2 mutations as prognostic indicators in non-promyelocytic acute myeloid leukemia: a meta-analysis
Kuang-Guo Zhou, Li-Jun Jiang, Zhen Shang, Jue Wang, Liang Huang & Jian-Feng Zhou
Pages: 2423-2429
Published online: 18 Jun 2012
AbstractforPotential application of IDH1 and IDH2 mutations as prognostic indicators in non-promyelocytic acute myeloid leukemia: a meta-analysis | Full Text | References | PDF (459.7 KB) | Supplemental
  • 578 Views
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Article
Chronic myeloid leukemia in children and adolescents: results of treatment with imatinib mesylate
K. C. Lakshmaiah, Rohan Bhise, Samit Purohit, Linu J. Abraham, D. Lokanatha, T. M. Suresh, L. Appaji, B. S. Arunakumari & K. Govindbabu
Pages: 2430-2433
Published online: 18 May 2012
AbstractforChronic myeloid leukemia in children and adolescents: results of treatment with imatinib mesylate | Full Text | References | PDF (180.3 KB) | Supplemental
  • 319 Views
  • 17 CrossRef citations
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Article
New recurrent chromosome change in pediatric therapy-related myelodysplastic syndrome: unbalanced translocation 1/6 with cryptic duplication of short arm of chromosome 6
Elisa Tassano, Elisa Tavella, Roberto Valli, Concetta Micalizzi, Cristina Cuoco, Emanuela Maserati, Francesco Pasquali & Cristina Morerio
Pages: 2434-2438
Published online: 13 Jun 2012
AbstractforNew recurrent chromosome change in pediatric therapy-related myelodysplastic syndrome: unbalanced translocation 1/6 with cryptic duplication of short arm of chromosome 6 | Full Text | References | PDF (342.2 KB) | Supplemental
  • 132 Views
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Article
Prognostic features of patients with myelodysplastic syndromes aged < 50 years: update of a single-institution experience
Massimo Breccia, Paola Finsinger, Giuseppina Loglisci, Michelina Santopietro, Adriano Salaroli, Alessandra Serrao, Roberto Latagliata, Paola Volpicelli, Luigi Petrucci, Mauro Nanni & Giuliana Alimena
Pages: 2439-2443
Published online: 09 Jul 2012
AbstractforPrognostic features of patients with myelodysplastic syndromes aged < 50 years: update of a single-institution experience | Full Text | References | PDF (161.9 KB) | Supplemental
  • 201 Views
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Article
Association of age with fluorescence in situ hybridization abnormalities in multiple myeloma reveals higher rate of IGH translocations among older patients
Charles Butler, Daynna J. Wolff, Yubin Kang, Robert K. Stuart & Luciano J. Costa
Pages: 2444-2448
Published online: 31 May 2012
AbstractforAssociation of age with fluorescence in situ hybridization abnormalities in multiple myeloma reveals higher rate of IGH translocations among older patients | Full Text | References | PDF (306.9 KB) | Supplemental
  • 175 Views
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Original Articles: Research

Article
Recurrent breakpoints in 14q32.13/TCL1A region in mature B-cell neoplasms with villous lymphocytes
Helena Urbankova, Mathijs Baens, Lucienne Michaux, Thomas Tousseyn, Katrina Rack, Beata Katrincsakova, Julio Finalet Ferreiro, Peter van Loo, Wim de Kelver, Daan Dierickx, Hilde Demuynck, André Delannoy, Johan Verschuere, Marie Jarošová, Chris de Wolf-Peeters, Peter Vandenberghe & Iwona Wlodarska
Pages: 2449-2455
Published online: 04 May 2012
AbstractforRecurrent breakpoints in 14q32.13/TCL1A region in mature B-cell neoplasms with villous lymphocytes | Full Text | References | PDF (496.5 KB) | Supplemental
  • 301 Views
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Research Article

Article
Novel function of scutellarin in inhibiting cell proliferation and inducing cell apoptosis of human Burkitt lymphoma Namalwa cells
Yizhong Feng, Shasha Zhang, Jian Tu, Zhifei Cao, Yanyan Pan, Bingxue Shang, Ruifang Liu, Meimei Bao, Pengda Guo & Quansheng Zhou
Pages: 2456-2464
Published online: 07 Jun 2012
AbstractforNovel function of scutellarin in inhibiting cell proliferation and inducing cell apoptosis of human Burkitt lymphoma Namalwa cells | Full Text | References | PDF (482.7 KB) | Supplemental
  • 234 Views
  • 41 CrossRef citations
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Article
Aberrant microRNA-182 expression is associated with glucocorticoid resistance in lymphoblastic malignancies
Apeng Yang, Jiexian Ma, Min Wu, Wenming Qin, Botao Zhao, Yi Shi, Youxin Jin & Yanhui Xie
Pages: 2465-2473
Published online: 18 Jun 2012
AbstractforAberrant microRNA-182 expression is associated with glucocorticoid resistance in lymphoblastic malignancies | Full Text | References | PDF (480 KB) | Supplemental
  • 323 Views
  • 25 CrossRef citations
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Article
Chronic myeloid leukemia stem cells display alterations in expression of genes involved in oxidative phosphorylation
Krzysztof Flis, David Irvine, Mhairi Copland, Ravi Bhatia & Tomasz Skorski
Pages: 2474-2478
Published online: 18 Jun 2012
AbstractforChronic myeloid leukemia stem cells display alterations in expression of genes involved in oxidative phosphorylation | Full Text | References | PDF (766.7 KB) | Supplemental
  • 607 Views
  • 25 CrossRef citations
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Article
Detection of JAK2 mutations in paraffin marrow biopsies by high resolution melting analysis: identification of L611S alone and in cis with V617F in polycythemia vera
Roberto H. Nussenzveig, Tatiana Burjanivova, Mohamed E. Salama, Natalie W. Ogilvie, Juraj Marcinek, Lukas Plank, Archana M. Agarwal, Sherrie L. Perkins & Josef T. Prchal
Pages: 2479-2486
Published online: 09 Jul 2012
AbstractforDetection of JAK2 mutations in paraffin marrow biopsies by high resolution melting analysis: identification of L611S alone and in cis with V617F in polycythemia vera | Full Text | References | PDF (439.3 KB) | Supplemental
  • 266 Views
  • 10 CrossRef citations
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Article
Synergistic/additive interaction of valproic acid with bortezomib on proliferation and apoptosis of acute myeloid leukemia cells
Danian Nie, Kezhi Huang, Songmei Yin, Yiqing Li, Shuangfeng Xie, Liping Ma, Xiuju Wang, Yudan Wu & Jie Xiao
Pages: 2487-2495
Published online: 18 Jun 2012
AbstractforSynergistic/additive interaction of valproic acid with bortezomib on proliferation and apoptosis of acute myeloid leukemia cells | Full Text | References | PDF (509.1 KB) | Supplemental
  • 317 Views
  • 18 CrossRef citations
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Letters to the Editor

Letter
Absence of BRAF V600E mutation in a cohort of 402 patients with various chronic and acute myeloid neoplasms
Adrian P. Trifa, Radu A. Popp, Andrei Cucuianu, Camelia A. Coadă, Laura G. Urian, Mariela S. Militaru, Claudia Bănescu, Delia Dima, Marius F. Farcaş, Tania O. Crişan, Ljubomir Petrov, Cristina Gug & Ioan V. Pop
Pages: 2496-2497
Published online: 18 Apr 2012
CitationforAbsence of BRAF V600E mutation in a cohort of 402 patients with various chronic and acute myeloid neoplasms | Full Text | References | PDF (146.9 KB) | Supplemental
  • 237 Views
  • 14 CrossRef citations
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Letter

Letter
Absence of BRAF V600E mutation in hematologic malignancies excluding hairy-cell leukemia
Nana Ping, Qinrong Wang, Qian Wang, Shasha Dong, Lili Wu, Yongquan Xue, Changgeng Ruan, Depei Wu & Suning Chen
Pages: 2498-2499
Published online: 09 Jul 2012
CitationforAbsence of BRAF V600E mutation in hematologic malignancies excluding hairy-cell leukemia | Full Text | References | PDF (149 KB) | Supplemental
  • 308 Views
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Letter
1q21 amplification with additional genetic abnormalities but not isolated 1q21 gain is a negative prognostic factor in newly diagnosed patients with multiple myeloma treated with thalidomide-based regimens
Norbert Grzasko, Marek Hus, Sylwia Chocholska, Andrzej Pluta, Roman Hajek & Anna Dmoszynska
Pages: 2500-2503
Published online: 22 May 2012
First Page Previewfor1q21 amplification with additional genetic abnormalities but not isolated 1q21 gain is a negative prognostic factor in newly diagnosed patients with multiple myeloma treated with thalidomide-based regimens | Full Text | References | PDF (250.7 KB) | Supplemental
  • 362 Views
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Letter
Epstein–Barr virus-associated B-cell lymphoma of the spleen resembling infectious mononucleosis morphologically
Masaru Kojima, Masahiro Noro, Yoshimasa Nakazato, Bunshiro Akikusa, Jun-ichi Tamaru, Nobuhide Masawa & Makoto Kashimura
Pages: 2504-2506
Published online: 21 May 2012
First Page PreviewforEpstein–Barr virus-associated B-cell lymphoma of the spleen resembling infectious mononucleosis morphologically | Full Text | References | PDF (325.4 KB) | Supplemental
  • 112 Views
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Letter
High-dose melphalan with bortezomib as conditioning regimen for autologous stem cell transplant in patients with newly diagnosed multiple myeloma who exhibited at least very good partial response to bortezomib-based induction therapy
Wenrong Huang, Jian Li, Honghua Li, Wenying Kang, Jian Bo, Yu Zhao, Chunji Gao, Daobin Zhou & Li Yu
Pages: 2507-2510
Published online: 22 May 2012
First Page PreviewforHigh-dose melphalan with bortezomib as conditioning regimen for autologous stem cell transplant in patients with newly diagnosed multiple myeloma who exhibited at least very good partial response to bortezomib-based induction therapy | Full Text | References | PDF (171.7 KB) | Supplemental
  • 379 Views
  • 10 CrossRef citations
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Letter
Myeloid sarcoma of the heart
Raya Mawad, David Wu, Janis L. Abkowitz & Roland B. Walter
Pages: 2511-2514
Published online: 21 May 2012
First Page PreviewforMyeloid sarcoma of the heart | Full Text | References | PDF (737.6 KB) | Supplemental
  • 211 Views
  • 5 CrossRef citations
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Letter
Panhypopituitarism and diabetes insipidus in a patient with primary central nervous system lymphoma
Olivier Malaise, Nicolas Frusch, Emmanuel Beck, Sophie Servais, Jo Caers, Jo Caers, Bernard de Prijck, Daniela Betea & Yves Beguin
Pages: 2515-2516
Published online: 21 May 2012
CitationforPanhypopituitarism and diabetes insipidus in a patient with primary central nervous system lymphoma | Full Text | References | PDF (147.6 KB) | Supplemental
  • 111 Views
  • 3 CrossRef citations
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Letter
MicroRNA profiling in pediatric acute lymphoblastic leukemia: novel prognostic tools
Neda Mosakhani, Virinder Kaur Sarhadi, Anu Usvasalo, Marja-Liisa Karjalainen-Lindsberg, Leo Lahti, Katja Tuononen, Ulla M. Saarinen-Pihkala & Sakari Knuutila
Pages: 2517-2520
Published online: 22 May 2012
First Page PreviewforMicroRNA profiling in pediatric acute lymphoblastic leukemia: novel prognostic tools | Full Text | References | PDF (283.9 KB) | Supplemental
  • 208 Views
  • 7 CrossRef citations
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Letter
A hemodialysis patient with higher-risk myelodysplastic syndrome treated with standard-dose azacitidine
Johanna C. Ham, Judith M. Hoogendijk-van den Akker & Leo F. Verdonck
Pages: 2521-2522
Published online: 21 May 2012
CitationforA hemodialysis patient with higher-risk myelodysplastic syndrome treated with standard-dose azacitidine | Full Text | References | PDF (127.8 KB) | Supplemental
  • 1046 Views
  • 6 CrossRef citations
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Letter
Negative impact of FLT3-ITD mutation on expression of MDR-1 mRNA in adult acute myeloid leukemia
Barbara Nasiłowska-Adamska & Iwona Solarska
Pages: 2523-2526
Published online: 16 May 2012
First Page PreviewforNegative impact of FLT3-ITD mutation on expression of MDR-1 mRNA in adult acute myeloid leukemia | Full Text | References | PDF (210.4 KB) | Supplemental
  • 92 Views
  • 2 CrossRef citations
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Letter
Bortezomib and dexamethasone as first-line therapy for a patient with newly diagnosed polyneuropathy, organomegaly, endocrinopathy, M protein and skin changes syndrome complicated by renal failure
Jian Li, Wei Zhang, Wen-Ying Kang, Xin-Xin Cao, Ming-Hui Duan & Dao-Bin Zhou
Pages: 2527-2529
Published online: 12 Jun 2012
First Page PreviewforBortezomib and dexamethasone as first-line therapy for a patient with newly diagnosed polyneuropathy, organomegaly, endocrinopathy, M protein and skin changes syndrome complicated by renal failure | Full Text | References | PDF (183.4 KB) | Supplemental
  • 244 Views
  • 15 CrossRef citations
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Letter
First case of donor transmitted non-leukemic promyelocytic sarcoma
Travis Williams, Omar S. Aljitawi, Ronnie Moussa, Sarah McHugh, Reginald Dusing, Joseph Abraha & Sri G. Yarlagadda
Pages: 2530-2534
Published online: 09 Jul 2012
First Page PreviewforFirst case of donor transmitted non-leukemic promyelocytic sarcoma | Full Text | References | PDF (366.1 KB) | Supplemental
  • 133 Views
  • 5 CrossRef citations
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