Leukemia & Lymphoma, Volume 60, Issue 12 (2019)

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Leukemia & Lymphoma, Volume 60, Issue 12 (2019)

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Commentary

Article Commentary
Lymphoblastic leukemia following MDS or MDS/MPN: clinical evidence for stem cell origins of these disorders
Sandeep Gurbuxani
Pages: 2847-2848
Published online: 26 Sep 2019
CitationforLymphoblastic leukemia following MDS or MDS/MPN: clinical evidence for stem cell origins of these disorders | Full Text | References | PDF (346.6 KB) | EPUB
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Article Commentary
Methotrexate and asparaginase: not so simple
Paul S. Gaynon
Pages: 2849-2850
Published online: 26 Sep 2019
CitationforMethotrexate and asparaginase: not so simple | Full Text | References | PDF (236.4 KB) | EPUB
  • 183 Views
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Article Commentary
Mold-active prophylaxis in acute leukemia: not enough of a good thing?
Emma Paige, Karin Thursky & Monica Slavin
Pages: 2851-2853
Published online: 23 Jul 2019
First Page PreviewforMold-active prophylaxis in acute leukemia: not enough of a good thing? | Full Text | References | PDF (585.1 KB) | EPUB
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Review

Review
A single-center multidisciplinary approach to managing the global Erwinia asparaginase shortage
Bernard L. Marini, Julia Brown, Lydia Benitez, Emily Walling, Raymond J. Hutchinson, Rajen Mody, Rama Jasty Rao, Lynn Slagle, Lauren Bishop, Kristen Pettit, Dale L. Bixby, Patrick W. Burke & Anthony J. Perissinotti
Pages: 2854-2868
Published online: 17 May 2019
AbstractforA single-center multidisciplinary approach to managing the global Erwinia asparaginase shortage | Full Text | References | PDF (1.3 MB) | EPUB
  • 1517 Views
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Article
Hairy cell leukemia: present and future directions
Robert J. Kreitman
Pages: 2869-2879
Published online: 09 May 2019
AbstractforHairy cell leukemia: present and future directions | Full Text | References | PDF (896.3 KB) | EPUB
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Original Article

Article
Clinicopathologic correlates of MYD88 L265P mutation and programmed cell death (PD-1) pathway in primary central nervous system lymphoma
Tarsheen K. Sethi, Alexandra E. Kovach, Natalie S. Grover, Li-Ching Huang, Laura A. Lee, Samuel M. Rubinstein, Yang Wang, David S. Morgan, John P. Greer, Steven I. Park, Mary Ann Thompson-Arildsen, Ashwini Yenamandra, Cindy L. Vnencak-Jones & Nishitha M. Reddy
Pages: 2880-2889
Published online: 11 Jun 2019
AbstractforClinicopathologic correlates of MYD88 L265P mutation and programmed cell death (PD-1) pathway in primary central nervous system lymphoma | Full Text | References | PDF (1.8 MB) | EPUB | Supplemental
  • 478 Views
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Article
Bleomycin, vinblastine and dacarbazine combined with nonpegylated liposomal doxorubicin (MBVD) in elderly (≥70 years) or cardiopathic patients with Hodgkin lymphoma: a phase-II study from Fondazione Italiana Linfomi (FIL)
Flavia Salvi, Stefano Luminari, Alessandra Tucci, Stefania Massidda, Anna Marina Liberati, Caterina Stelitano, Manuela Zanni, Alessandro Re, Riccardo Centurioni, Roberto Freilone, Gerardo Musuraca, Luca Nassi, Caterina Patti, Annalisa Arcari, Monica Tani, Alessandro Pulsoni, Vincenzo Pavone, Stefano Volpetti, Annalisa Peli, Andrea Evangelista, Michele Spina, Marco Ladetto & Francesco Merli
Pages: 2890-2898
Published online: 08 Jul 2019
AbstractforBleomycin, vinblastine and dacarbazine combined with nonpegylated liposomal doxorubicin (MBVD) in elderly (≥70 years) or cardiopathic patients with Hodgkin lymphoma: a phase-II study from Fondazione Italiana Linfomi (FIL) | Full Text | References | PDF (739.2 KB) | EPUB
  • 419 Views
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Article
The association between HLA and non-Hodgkin lymphoma subtypes, among a transplant-indicated population
Charlie Zhong, Loren Gragert, Martin Maiers, Brian T. Hill, Jean Garcia-Gomez, Ketevan Gendzekhadze, David Senitzer, Joo Song, Dennis Weisenburger, Leanne Goldstein & Sophia S. Wang
Pages: 2899-2908
Published online: 19 Jun 2019
AbstractforThe association between HLA and non-Hodgkin lymphoma subtypes, among a transplant-indicated population | Full Text | References | PDF (1.2 MB) | EPUB | Supplemental
  • 2165 Views
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Open Access
Article
Peripheral blood lymphocyte subsets of newly diagnosed DLBCL patients and their dynamic changes with rituximab based immunochemotherapy
Zhiluo Yang, Wei Yu, Shuguo Wang, Xia Zhou, Shuangshuang Liu & Shupei Ma
Pages: 2909-2916
Published online: 23 May 2019
AbstractforPeripheral blood lymphocyte subsets of newly diagnosed DLBCL patients and their dynamic changes with rituximab based immunochemotherapy | Full Text | References | PDF (962.2 KB) | EPUB
  • 228 Views
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Article
A phase I trial of palbociclib plus bortezomib in previously treated mantle cell lymphoma
Peter Martin, Jia Ruan, Richard Furman, Sarah Rutherford, John Allan, Zhengming Chen, Xiangao Huang, Maurizio DiLiberto, Selina Chen-Kiang & John P. Leonard
Pages: 2917-2921
Published online: 23 May 2019
AbstractforA phase I trial of palbociclib plus bortezomib in previously treated mantle cell lymphoma | Full Text | References | PDF (604.2 KB) | EPUB
  • 451 Views
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Article
Prevalence and clinical significance of hypercalcemia at diagnosis in diffuse large B-cell lymphoma
Uri Abadi, Lee Peled, Ronit Gurion, Pnina Rotman-Pikielny, Pia Raanani, Martin H. Ellis & Uri Rozovski
Pages: 2922-2926
Published online: 06 Jun 2019
AbstractforPrevalence and clinical significance of hypercalcemia at diagnosis in diffuse large B-cell lymphoma | Full Text | References | PDF (504.8 KB) | EPUB
  • 366 Views
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Article
Effect of leucovorin administration on mucositis and skin reactions in patients with peripheral T-cell lymphoma or cutaneous T-cell lymphoma treated with pralatrexate*
Francine M. Foss, Terri L. Parker, Michael Girardi & Anlong Li
Pages: 2927-2930
Published online: 23 May 2019
AbstractforEffect of leucovorin administration on mucositis and skin reactions in patients with peripheral T-cell lymphoma or cutaneous T-cell lymphoma treated with pralatrexate* | Full Text | References | PDF (363.1 KB) | EPUB
  • 479 Views
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Article
Phase 1 study of lenalidomide, bendamustine, and rituximab in previously untreated patients with chronic lymphocytic leukemia
Jacob D. Soumerai, Matthew S. Davids, Lillian Werner, David C. Fisher, Philippe Armand, Philip C. Amrein, Donna Neuberg, Ephraim P. Hochberg, Jennifer R. Brown & Jeremy S. Abramson
Pages: 2931-2938
Published online: 10 May 2019
AbstractforPhase 1 study of lenalidomide, bendamustine, and rituximab in previously untreated patients with chronic lymphocytic leukemia | Full Text | References | PDF (729.4 KB) | EPUB
  • 261 Views
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Article
Safety and efficacy analysis of long-term follow up real-world data with ibrutinib monotherapy in 58 patients with CLL treated in a single-center in Greece
Maria Dimou, Theodoros Iliakis, Vasileios Pardalis, Catherin Bitsani, Theodoros P. Vassilakopoulos, Maria Angelopoulou, Panayiotis Tsaftaridis, Paraskevi Papaioannou, Aspasia Koudouna, Sotiria Kalyva, Marie-Christine Kyrtsonis & Panayiotis Panayiotidis
Pages: 2939-2945
Published online: 11 Jun 2019
AbstractforSafety and efficacy analysis of long-term follow up real-world data with ibrutinib monotherapy in 58 patients with CLL treated in a single-center in Greece | Full Text | References | PDF (693.3 KB) | EPUB
  • 518 Views
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Article
Pharmacologic inhibition of the ubiquitin-activating enzyme induces ER stress and apoptosis in chronic lymphocytic leukemia and ibrutinib-resistant mantle cell lymphoma cells
Scott Best, Tingting Liu, Nur Bruss, Adam Kittai, Allison Berger & Alexey V. Danilov
Pages: 2946-2950
Published online: 21 May 2019
AbstractforPharmacologic inhibition of the ubiquitin-activating enzyme induces ER stress and apoptosis in chronic lymphocytic leukemia and ibrutinib-resistant mantle cell lymphoma cells | Full Text | References | PDF (801 KB) | EPUB
  • 485 Views
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Article
Cost-effectiveness analysis on binary/triple therapy on the basis of ixazomib or bortezomib for refractory or relapsed multiple myeloma
Hongfu Cai, Longfeng Zhang, Na Li, Bin Zheng & Maobai Liu
Pages: 2951-2959
Published online: 04 Jun 2019
AbstractforCost-effectiveness analysis on binary/triple therapy on the basis of ixazomib or bortezomib for refractory or relapsed multiple myeloma | Full Text | References | PDF (1.4 MB) | EPUB
  • 595 Views
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Article
Development of thrombocytopenia during first-line treatment and survival outcomes in newly diagnosed multiple myeloma
Patrick W. Mellors, Moritz Binder, Francis K. Buadi, Martha Q. Lacy, Morie A. Gertz, Angela Dispenzieri, Suzanne R. Hayman, Prashant Kapoor, Wilson I. Gonsalves, Yi L. Hwa, Amie Fonder, Miriam Hobbs, Taxiarchis Kourelis, Rahma Warsame, Steven R. Zeldenrust, John A. Lust, Nelson Leung, Ronald S. Go, Robert A. Kyle, S. Vincent Rajkumar & Shaji K. Kumar
Pages: 2960-2967
Published online: 16 May 2019
AbstractforDevelopment of thrombocytopenia during first-line treatment and survival outcomes in newly diagnosed multiple myeloma | Full Text | References | PDF (2.2 MB) | EPUB
  • 304 Views
  • 4 CrossRef citations
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Article
Smoldering multiple myeloma: the role of different scoring systems in identifying high-risk patients in real-life practice
Federica Cocito, Silvia Mangiacavalli, Virginia Valeria Ferretti, Claudio Salvatore Cartia, Maya Ganzetti, Pietro Benveuti, Alessandra Pompa, Martina Catalano, Elena Fugazza, Benedetta Landini, Luca Arcaini & Alessandro Corso
Pages: 2968-2974
Published online: 06 Jun 2019
AbstractforSmoldering multiple myeloma: the role of different scoring systems in identifying high-risk patients in real-life practice | Full Text | References | PDF (573.6 KB) | EPUB
  • 452 Views
  • 5 CrossRef citations
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Article
Impact of prior bortezomib therapy on the incidence of lenalidomide-induced skin rash in multiple myeloma: a propensity score-matched multi-institutional cohort study
Satoshi Dote, Kaori Ito, Shoji Itakura, Takeo Yasu, Daiki Hira, Satoshi Noda, Shigeki Yamada, Yuka Kobayashi & Tomohiro Terada
Pages: 2975-2981
Published online: 03 May 2019
AbstractforImpact of prior bortezomib therapy on the incidence of lenalidomide-induced skin rash in multiple myeloma: a propensity score-matched multi-institutional cohort study | Full Text | References | PDF (947.5 KB) | EPUB | Supplemental
  • 368 Views
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Article
Management of cardiovascular health in acute leukemia: a national survey
Michelle Durand, Katie Lacaria, Margaret Sidsworth, Margot K. Davis & David Sanford
Pages: 2982-2992
Published online: 21 May 2019
AbstractforManagement of cardiovascular health in acute leukemia: a national survey | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
  • 167 Views
  • 2 CrossRef citations
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Article
Lymphoblastic leukemia following myelodysplastic syndromes or myelodysplastic/myeloproliferative neoplasms
Wei Xie, Zhining Chen, Sa A. Wang, Shimin Hu, Shaoying Li, Roberto N. Miranda, L. Jeffrey Medeiros & Guiling Tang
Pages: 2993-3001
Published online: 24 Apr 2019
AbstractforLymphoblastic leukemia following myelodysplastic syndromes or myelodysplastic/myeloproliferative neoplasms | Full Text | References | PDF (2.2 MB) | EPUB | Supplemental
  • 229 Views
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Article
The effect of asparaginase therapy on methotrexate toxicity and efficacy in children with acute lymphoblastic leukemia
Robin Q. H. Kloos, Rob Pieters, Cor van den Bos, Natasha K. A. van Eijkelenburg, Robert de Jonge & Inge M. van der Sluis
Pages: 3002-3010
Published online: 23 May 2019
AbstractforThe effect of asparaginase therapy on methotrexate toxicity and efficacy in children with acute lymphoblastic leukemia | Full Text | References | PDF (843.6 KB) | EPUB
  • 4566 Views
  • 10 CrossRef citations
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Open Access
Article
C-terminal BRE inhibits cellular proliferation and increases sensitivity to chemotherapeutic drugs of MLL-AF9 acute myeloid leukemia cells
Charmaine Cheuk-Man Pun, Kenneth Ka-Ho Lee & Yiu-Loon Chui
Pages: 3011-3019
Published online: 21 May 2019
AbstractforC-terminal BRE inhibits cellular proliferation and increases sensitivity to chemotherapeutic drugs of MLL-AF9 acute myeloid leukemia cells | Full Text | References | PDF (2.1 MB) | EPUB
  • 224 Views
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Article
Clinical applicability of proposed algorithm for identifying individuals at risk for hereditary hematologic malignancies
Maggie Clifford, Sarah Bannon, Erica M. Bednar, Jennifer Czerwinski, Jessica Davis, Leslie Dunnington, S. Shahrukh Hashmi & Courtney D. DiNardo
Pages: 3020-3027
Published online: 05 Jul 2019
AbstractforClinical applicability of proposed algorithm for identifying individuals at risk for hereditary hematologic malignancies | Full Text | References | PDF (880.3 KB) | EPUB
  • 330 Views
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Article
Infections in children with acute myeloid leukemia: increased mortality in relapsed/refractory patients
Olga Zając-Spychała, Jolanta Skalska-Sadowska, Jacek Wachowiak, Anna Szmydki-Baran, Łukasz Hutnik, Michał Matysiak, Filip Pierlejewski, Wojciech Młynarski, Krzysztof Czyżewski, Magdalena Dziedzic, Mariusz Wysocki, Patrycja Zalas-Więcek, Magdalena Bartnik, Tomasz Ociepa, Tomasz Urasiński, Zofia Małas, Wanda Badowska, Zuzanna Gamrot-Pyka, Mariola Woszczyk, Renata Tomaszewska, Tomasz Szczepański, Nina Irga-Jaworska, Elżbieta Drożyńska, Agnieszka Urbanek-Dądela, Grażyna Karolczyk, Marcin Płonowski, Maryna Krawczuk-Rybak, Jowita Frączkiewicz, Malgorzata Salamonowicz, Alicja Chybicka, Weronika Stolpa, Grazyna Sobol-Milejska, Liliana Chełmecka-Wiktorczyk, Walentyna Balwierz, Iwona Zak, Olga Gryniewicz–Kwiatkowska, Aneta Gietka, Bozenna Dembowska-Bagińska, Katarzyna Semczuk, Katarzyna Dzierżanowska-Fangrat, Jakub Musiał, Radoslaw Chaber, Jerzy Kowalczyk & Jan Styczyński
Pages: 3028-3035
Published online: 28 May 2019
AbstractforInfections in children with acute myeloid leukemia: increased mortality in relapsed/refractory patients | Full Text | References | PDF (963.2 KB) | EPUB | Supplemental
  • 443 Views
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Article
MMP-10 and TIMP-1 as indicators of severe sepsis in adult hematological patients with febrile neutropenia
Stefan Becker, Sini Korpelainen, Miika Arvonen, Sari Hämäläinen, Esa Jantunen, Marika Lappalainen, Kari Pulkki, Pekka Riikonen & Auni Juutilainen
Pages: 3036-3043
Published online: 24 May 2019
AbstractforMMP-10 and TIMP-1 as indicators of severe sepsis in adult hematological patients with febrile neutropenia | Full Text | References | PDF (1 MB) | EPUB
  • 165 Views
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Article
Invasive pulmonary aspergillosis in acute leukemia: a still frequent condition with a negative impact on the overall treatment outcome
Chiara Cattaneo, Doriana Gramegna, Michele Malagola, Chiara Pagani, Erika Borlenghi, Elisa Cerqui, Angela Passi, Margherita Sciumé, Simona Bernardi, Claudia Crippa, Daniela Dalceggio, Cecilia Carbone, Anna Maria Pelizzari, Alessandro Re, Domenico Russo & Giuseppe Rossi
Pages: 3044-3050
Published online: 23 May 2019
AbstractforInvasive pulmonary aspergillosis in acute leukemia: a still frequent condition with a negative impact on the overall treatment outcome | Full Text | References | PDF (672.1 KB) | EPUB
  • 340 Views
  • 17 CrossRef citations
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Article
Clinical characteristics and prognostic significance of chronic myeloid leukemia with rare BCR-ABL1 transcripts
Mengxing Xue, Qinrong Wang, Li Huo, Lijun Wen, Xiaofei Yang, Qian Wu, Jinlan Pan, Jiannong Cen, Changgeng Ruan, Depei Wu & Suning Chen
Pages: 3051-3057
Published online: 01 Jul 2019
AbstractforClinical characteristics and prognostic significance of chronic myeloid leukemia with rare BCR-ABL1 transcripts | Full Text | References | PDF (759.9 KB) | EPUB
  • 262 Views
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Letter to the Editor

Letter
Cardiac and genetic predictors of cardiovascular risk in patients with myelodysplastic syndromes
Evan C. Chen, Lillian Werner, Gabriela S. Hobbs, Rupa Narayan, Philip C. Amrein, Amir T. Fathi & Andrew M. Brunner
Pages: 3058-3062
Published online: 23 May 2019
First Page PreviewforCardiac and genetic predictors of cardiovascular risk in patients with myelodysplastic syndromes | Full Text | References | PDF (726.1 KB) | EPUB
  • 120 Views
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Letter
Induction of apoptosis by MCL-1 inhibitors in chronic lymphocytic leukemia cells
Lisa S. Chen, Michael J. Keating, William G. Wierda & Varsha Gandhi
Pages: 3063-3066
Published online: 04 Jun 2019
First Page PreviewforInduction of apoptosis by MCL-1 inhibitors in chronic lymphocytic leukemia cells | Full Text | References | PDF (623.7 KB) | EPUB | Supplemental
  • 275 Views
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Letter
Insights into the cellular pharmacological properties of the BET-inhibitor OTX015/MK-8628 (birabresib), alone and in combination, in leukemia models
Lucile Astorgues-Xerri, Ramiro Vázquez, Elodie Odore, Keyvan Rezai, Carmen Kahatt, Sarah Mackenzie, Mohamed Bekradda, Marie-Magdelaine Coudé, Herve Dombret, Claude Gardin, Francois Lokiec, Eric Raymond, Kay Noel, Esteban Cvitkovic, Patrice Herait, Francesco Bertoni & María E. Riveiro
Pages: 3067-3070
Published online: 17 Jun 2019
First Page PreviewforInsights into the cellular pharmacological properties of the BET-inhibitor OTX015/MK-8628 (birabresib), alone and in combination, in leukemia models | Full Text | References | PDF (1 MB) | EPUB | Supplemental
  • 208 Views
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Letter
Anti-leukemia effect of vitamin K3 is mediated through mitochondrial complexes I and II
Medhat Ibrahim, Nilmini Mendis, Alessia Roma, Preethi Jayanth, Mark D. Minden & Paul A. Spagnuolo
Pages: 3071-3074
Published online: 04 Jun 2019
First Page PreviewforAnti-leukemia effect of vitamin K3 is mediated through mitochondrial complexes I and II | Full Text | References | PDF (477.7 KB) | EPUB
  • 125 Views
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Letter
Reduced intensity alemtuzumab-containing allogeneic stem cell transplantation for relapsed/refractory low grade lymphoma: reflections on a single center experience
Claire Horgan, Shereef Elmoamly, Graham McIlroy, David Davies, Maria Kaparou, Hannah Giles, Evgenia Xenou, Bhuvan Kishore, Richard Lovell, Emmanouil Nikolousis, Paneesha Shankara & Alexandros Kanellopoulos
Pages: 3075-3077
Published online: 13 May 2019
First Page PreviewforReduced intensity alemtuzumab-containing allogeneic stem cell transplantation for relapsed/refractory low grade lymphoma: reflections on a single center experience | Full Text | References | PDF (295.8 KB) | EPUB
  • 90 Views
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Letter
Remission of acquired von Willebrand syndrome in a patient with chronic lymphocytic leukemia treated with venetoclax
Idanna Innocenti, Francesca Morelli, Francesco Autore, Annamaria Tomasso, Andrea Corbingi, Silvia Bellesi, Tommaso Za, Valerio De Stefano & Luca Laurenti
Pages: 3078-3080
Published online: 20 May 2019
First Page PreviewforRemission of acquired von Willebrand syndrome in a patient with chronic lymphocytic leukemia treated with venetoclax | Full Text | References | PDF (618.3 KB) | EPUB
  • 131 Views
  • 2 CrossRef citations
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Letter to theEditor

Letter
Cytomegalovirus DNAemia in patients with de novo acute myeloid leukemia undergoing cytotoxic chemotherapy
Mar Tormo, Estela Giménez, Marisa Calabuig, Alberto Talaya, Blanca Navarro, Paula Amat, Iván Martín, Eliseo Albert, Carlos Solano & David Navarro
Pages: 3081-3083
Published online: 21 May 2019
First Page PreviewforCytomegalovirus DNAemia in patients with de novo acute myeloid leukemia undergoing cytotoxic chemotherapy | Full Text | References | PDF (409.7 KB) | EPUB
  • 93 Views
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Letter to the Editor

Letter
Lenalidomide-induced tubulointerstitial nephritis in Hodgkin lymphoma
Alex Dinh, Matthew B. Palmer, Jakub Svoboda & Jonathan J. Hogan
Pages: 3084-3086
Published online: 24 May 2019
First Page PreviewforLenalidomide-induced tubulointerstitial nephritis in Hodgkin lymphoma | Full Text | References | PDF (724.7 KB) | EPUB
  • 135 Views
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Letter
Successful desensitization to pomalidomide in a patient with POEMS syndrome with delayed-type hypersensitivity to immunomodulatory imid drugs
Francesco Grandoni, Grégoire Stalder, Amélie Borgeat Kaeser, Camillo Ribi, Anne Cairoli & Sabine Blum
Pages: 3087-3089
Published online: 04 Jun 2019
First Page PreviewforSuccessful desensitization to pomalidomide in a patient with POEMS syndrome with delayed-type hypersensitivity to immunomodulatory imid drugs | Full Text | References | PDF (510.7 KB) | EPUB
  • 482 Views
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Letter
Blast crisis of chronic myeloid leukemia with plasmacytoid dendritic cell phenotype associated with a rare fusion transcript, e13a3 BCR–ABL1
Danmei Xu, Simone Claudiani, Kikkeri Naresh, Stuart Mucklow, Pratap Neelakantan, Eva Yebra, Jane F. Apperley, Jamshid Khorashad & Dragana Milojkovic
Pages: 3090-3091
Published online: 11 Jun 2019
CitationforBlast crisis of chronic myeloid leukemia with plasmacytoid dendritic cell phenotype associated with a rare fusion transcript, e13a3 BCR–ABL1 | Full Text | References | PDF (852.6 KB) | EPUB
  • 127 Views
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Letter
Plasma exchange following mogamulizumab therapy before bone marrow transplantation in refractory adult T-cell leukemia–lymphoma
Yutaka Shimazu & Masaharu Nohgawa
Pages: 3092-3093
Published online: 20 May 2019
CitationforPlasma exchange following mogamulizumab therapy before bone marrow transplantation in refractory adult T-cell leukemia–lymphoma | Full Text | References | PDF (347.7 KB) | EPUB
  • 76 Views
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