Leukemia & Lymphoma, Volume 62, Issue 5 (2021)

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Leukemia & Lymphoma, Volume 62, Issue 5 (2021)

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Commentary

Article Commentary
Idelalisib in indolent NHL – has it finally found its niche?
Aswin Sekar & Matthew S. Davids
Pages: 1029-1030
Published online: 19 Oct 2020
CitationforIdelalisib in indolent NHL – has it finally found its niche? | Full Text | References | PDF (242.8 KB) | EPUB
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Reviews

Genetic complexity of chronic myelomonocytic leukemia
Ami B. Patel & Michael W. Deininger
Pages: 1031-1045
Published online: 18 Dec 2020
AbstractforGenetic complexity of chronic myelomonocytic leukemia | Full Text | References | PDF (1.8 MB) | EPUB
  • 577 Views
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Evolving management strategies for lymphomas during the COVID-19 pandemic
Noemie Lang & John Kuruvilla
Pages: 1046-1056
Published online: 25 Dec 2020
AbstractforEvolving management strategies for lymphomas during the COVID-19 pandemic | Full Text | References | PDF (931.1 KB) | EPUB
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Nodular lymphocyte predominant Hodgkin lymphoma: executive summary of the American radium society appropriate use criteria
Leslie K. Ballas, Monika L. Metzger, Sarah A. Milgrom, Ranjana Advani, Richard L. Bakst, Bouthaina S. Dabaja, Christopher R. Flowers, Chul S. Ha, Bradford S. Hoppe, David B. Mansur, Chelsea C. Pinnix, John P. Plastaras, Kenneth B. Roberts, Sonali M. Smith, Stephanie A. Terezakis & Louis S. Constine
Pages: 1057-1065
Published online: 04 Dec 2020
AbstractforNodular lymphocyte predominant Hodgkin lymphoma: executive summary of the American radium society appropriate use criteria | Full Text | References | PDF (749.4 KB) | EPUB | Supplemental
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Emerging Drug Profile

Article
Acalabrutinib: a highly selective, potent Bruton tyrosine kinase inhibitor for the treatment of chronic lymphocytic leukemia
Paolo Ghia, Monika Dlugosz-Danecka, Lydia Scarfò & Wojciech Jurczak
Pages: 1066-1076
Published online: 11 Jan 2021
AbstractforAcalabrutinib: a highly selective, potent Bruton tyrosine kinase inhibitor for the treatment of chronic lymphocytic leukemia | Full Text | References | PDF (1.6 MB) | EPUB
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Original Articles

Article
Outcomes of patients with up to 6 years of follow-up from a phase 2 study of idelalisib for relapsed indolent lymphomas
Nina D. Wagner-Johnston, Stephen J. Schuster, Sven deVos, Gilles Salles, Wojciech J. Jurczak, Christopher R. Flowers, Andreas Viardot, Ian W. Flinn, Peter Martin, Guan Xing, Nishanthan Rajakumaraswamy & Ajay K. Gopal
Pages: 1077-1087
Published online: 10 Dec 2020
AbstractforOutcomes of patients with up to 6 years of follow-up from a phase 2 study of idelalisib for relapsed indolent lymphomas | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
  • 546 Views
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Article
SUVmax-based assessment of PET response shows a superior specificity to Deauville criteria for predicting recurrence in Hodgkin’s lymphoma
Edgar Texte, Justine Lequesne, Hervé Tilly, Fabrice Jardin, Pierre Vera, Aspasia Stamatoullas & Stéphanie Becker
Pages: 1088-1097
Published online: 08 Dec 2020
AbstractforSUVmax-based assessment of PET response shows a superior specificity to Deauville criteria for predicting recurrence in Hodgkin’s lymphoma | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
  • 270 Views
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Article
Prognostic impact of the psoas muscle index, a parameter of sarcopenia, in patients with diffuse large B-cell lymphoma treated with rituximab-based chemoimmunotherapy
Utku Iltar, Hasan Sözel, Yıldız Kılar Sözel, Ünal Ataş, Orhan Kemal Yücel, Ozan Salim, Funda Aydin & Levent Undar
Pages: 1098-1106
Published online: 10 Dec 2020
AbstractforPrognostic impact of the psoas muscle index, a parameter of sarcopenia, in patients with diffuse large B-cell lymphoma treated with rituximab-based chemoimmunotherapy | Full Text | References | PDF (961.5 KB) | EPUB
  • 489 Views
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Article
Identification of a miRNA based model to detect prognostic subgroups in patients with aggressive B-cell lymphoma
Carmen Nordmo, Gunther Glehr, Michael Altenbuchinger, Rainer Spang, Marita Ziepert, Heike Horn, Annette M. Staiger, German Ott, Norbert Schmitz, Gerhard Held, Hermann Einsele, Max Topp, Andreas Rosenwald & Hilka Rauert-Wunderlich
Pages: 1107-1115
Published online: 22 Dec 2020
AbstractforIdentification of a miRNA based model to detect prognostic subgroups in patients with aggressive B-cell lymphoma | Full Text | References | PDF (949.7 KB) | EPUB | Supplemental
  • 188 Views
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Article
Expression of germinal center cell markers by extranodal marginal zone lymphomas of MALT type within colonized follicles, a diagnostic pitfall with follicular lymphoma
Julio Poveda, Daniel P. Cassidy, Yi Zhou, Juan Pablo Alderuccio, Izidore S. Lossos, Francisco Vega & Jennifer Chapman
Pages: 1116-1122
Published online: 07 Dec 2020
AbstractforExpression of germinal center cell markers by extranodal marginal zone lymphomas of MALT type within colonized follicles, a diagnostic pitfall with follicular lymphoma | Full Text | References | PDF (2.8 MB) | EPUB
  • 533 Views
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Article
Reduction of immunosuppression for post-transplant lymphoproliferative disorder (PTLD): a single-center experience of allograft survival outcomes
Kelsey Pan, Aaron J. Franke, William Paul Skelton IV, Rohit Bishnoi, Chintan Shah, Nam H. Dang & Kawther Alquadan
Pages: 1123-1128
Published online: 16 Dec 2020
AbstractforReduction of immunosuppression for post-transplant lymphoproliferative disorder (PTLD): a single-center experience of allograft survival outcomes | Full Text | References | PDF (1.1 MB) | EPUB
  • 341 Views
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Article
Expression of BCL2 alternative proteins and association with outcome in CLL patients treated with venetoclax
Mario L. Marques-Piubelli, Ellen J. Schlette, Joseph D. Khoury, Fateeha Furqan, Francisco Vega, Luisa M. Solis Soto, Ignacio I. Wistuba, William G. Wierda, Marina Konopleva, Alessandra Ferrajoli & Paolo Strati
Pages: 1129-1135
Published online: 17 Dec 2020
AbstractforExpression of BCL2 alternative proteins and association with outcome in CLL patients treated with venetoclax | Full Text | References | PDF (1.2 MB) | EPUB | Supplemental
  • 421 Views
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Article
Epidemiology, longitudinal treatment patterns and outcomes of chronic lymphocytic leukemia in Israel
Clara Weil, Gabriel Chodick, Varda Shalev, Inna Kan, Ran Afik, Raanan Cohen, Kavita Sail & Yair Herishanu
Pages: 1136-1145
Published online: 11 Dec 2020
AbstractforEpidemiology, longitudinal treatment patterns and outcomes of chronic lymphocytic leukemia in Israel | Full Text | References | PDF (1.4 MB) | EPUB | Supplemental
  • 358 Views
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Article
Tellurium compound provides pro-apoptotic signaling in drug resistant multiple myeloma
Eti Zigman-Hoffman, Benjamin Sredni, Benjamin Meilik, Ella Naparstek & Boris Tartakovsky
Pages: 1146-1156
Published online: 17 Dec 2020
AbstractforTellurium compound provides pro-apoptotic signaling in drug resistant multiple myeloma | Full Text | References | PDF (1.5 MB) | EPUB | Supplemental
  • 128 Views
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Article
In-vitro modeling of TKI resistance in the high-risk B-cell acute lymphoblastic leukemia fusion gene RANBP2-ABL1 - implications for targeted therapy
Susan L. Heatley, Kartini Asari, Caitlin E. Schutz, Tamara M. Leclercq, Barbara J. McClure, Laura N. Eadie, Timothy P. Hughes, David T. Yeung & Deborah L. White
Pages: 1157-1166
Published online: 02 Jan 2021
AbstractforIn-vitro modeling of TKI resistance in the high-risk B-cell acute lymphoblastic leukemia fusion gene RANBP2-ABL1 - implications for targeted therapy | Full Text | References | PDF (2.1 MB) | EPUB | Supplemental
  • 497 Views
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Article
CXCR4 allows T cell acute lymphoblastic leukemia to escape from JAK1/2 and BCL2 inhibition through CNS infiltration
Kirsti L. Walker, Sean P. Rinella, Nicholas J. Hess, David P. Turicek, Sabrina A. Kabakov, Fen Zhu, Myriam N. Bouchlaka, Sydney L. Olson, Monica M. Cho, Aicha E. Quamine, Arika S. Feils, Tara B. Gavcovich, Lixin Rui & Christian M. Capitini
Pages: 1167-1177
Published online: 11 Apr 2021
AbstractforCXCR4 allows T cell acute lymphoblastic leukemia to escape from JAK1/2 and BCL2 inhibition through CNS infiltration | Full Text | References | PDF (2.8 MB) | EPUB | Supplemental
  • 578 Views
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Article
Genetic biomarkers identify a subgroup of high-risk patients within low-risk NPM1-mutated acute myeloid leukemia
Diego Carbonell, Julia Suárez-González, María Chicano, Cristina Andrés-Zayas, Miriam Díez-Díez, Gabriela Rodríguez-Macías, Paula Muñiz, Mi Kwon, Javier Anguita, José Luis Díez-Martín, Ismael Buño & Carolina Martínez-Laperche
Pages: 1178-1186
Published online: 29 Dec 2020
AbstractforGenetic biomarkers identify a subgroup of high-risk patients within low-risk NPM1-mutated acute myeloid leukemia | Full Text | References | PDF (1.7 MB) | EPUB | Supplemental
  • 186 Views
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Article
Phase 1 study of belinostat (PXD-101) and bortezomib (Velcade, PS-341) in patients with relapsed or refractory acute leukemia and myelodysplastic syndrome
Beata Holkova, Danielle Shafer, Victor Yazbeck, Sandeep Dave, Prithviraj Bose, Mary Beth Tombes, Ellen Shrader, Wen Wan, Dipankar Bandyopadhyay, Caryn Weir, Elizabeth B. Collins, Amanda Garnett, Maciej Kmieciak, John D. Roberts, Guillermo Garcia-Manero & Steven Grant
Pages: 1187-1194
Published online: 28 Dec 2020
AbstractforPhase 1 study of belinostat (PXD-101) and bortezomib (Velcade, PS-341) in patients with relapsed or refractory acute leukemia and myelodysplastic syndrome | Full Text | References | PDF (888.5 KB) | EPUB | Supplemental
  • 254 Views
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Article
High dose cyclophosphamide for cytoreduction in patients with acute myeloid leukemia with hyperleukocytosis or leukostasis
Jennifer Zhao, Jan Philipp Bewersdorf, Sara Jaszczur, Andrew Kowalski, Sarah Perreault, Molly Schiffer, Steven Gore, Nikolai Podoltsev, Thomas Prebet, Rory Shallis & Amer M. Zeidan
Pages: 1195-1202
Published online: 16 Dec 2020
AbstractforHigh dose cyclophosphamide for cytoreduction in patients with acute myeloid leukemia with hyperleukocytosis or leukostasis | Full Text | References | PDF (936.6 KB) | EPUB
  • 642 Views
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Article
Adverse events among chronic myelogenous leukemia patients treated with tyrosine kinase inhibitors: a real-world analysis of health plan enrollees
Eric J. Chow, David R. Doody, Jennifer J. Wilkes, Laura K. Becker, Shasank Chennupati, Pamela E. Morin, Lena E. Winestone, Henry J. Henk & Gary H. Lyman
Pages: 1203-1210
Published online: 07 Dec 2020
AbstractforAdverse events among chronic myelogenous leukemia patients treated with tyrosine kinase inhibitors: a real-world analysis of health plan enrollees | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
  • 346 Views
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Article
Exploring the determinants that influence hospital costs of induction therapy for acute myeloid leukemia
Liqing Ning, Dengju Li, Pingfan Lu & Yimei Que
Pages: 1211-1218
Published online: 10 Dec 2020
AbstractforExploring the determinants that influence hospital costs of induction therapy for acute myeloid leukemia | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
  • 58 Views
  • 1 CrossRef citations
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Article
Nanopore sequencing sheds a light on the FLT3 gene mutations complexity in acute promyelocytic leukemia
Cosimo Cumbo, Paola Orsini, Luisa Anelli, Antonella Zagaria, Crescenzio Francesco Minervini, Nicoletta Coccaro, Giuseppina Tota, Luciana Impera, Elisa Parciante, Maria Rosa Conserva, Immacolata Redavid, Paola Carluccio, Francesco Tarantini, Giorgina Specchia, Pellegrino Musto & Francesco Albano
Pages: 1219-1225
Published online: 08 Dec 2020
AbstractforNanopore sequencing sheds a light on the FLT3 gene mutations complexity in acute promyelocytic leukemia | Full Text | References | PDF (1.9 MB) | EPUB | Supplemental
  • 284 Views
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Article
Comparison of myeloid blast counts and variant allele frequencies of gene mutations in myelodysplastic syndrome with excess blasts and secondary acute myeloid leukemia
Xueyan Chen, Megan Othus, Brent L. Wood, Roland B. Walter, Pamela S. Becker, Mary-Elizabeth Percival, Janis L. Abkowitz, Frederick R. Appelbaum & Elihu H. Estey
Pages: 1226-1233
Published online: 19 Dec 2020
AbstractforComparison of myeloid blast counts and variant allele frequencies of gene mutations in myelodysplastic syndrome with excess blasts and secondary acute myeloid leukemia | Full Text | References | PDF (940.7 KB) | EPUB
  • 471 Views
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Letters to the Editor

Disseminated ALK-positive histiocytosis with KIF5B-ALK fusion in an adult
Lianqun Qiu, Steven P. Weitzman, Loretta J. Nastoupil, Michelle D. Williams, L. Jeffrey Medeiros & Francisco Vega
Pages: 1234-1238
Published online: 22 Dec 2020
First Page PreviewforDisseminated ALK-positive histiocytosis with KIF5B-ALK fusion in an adult | Full Text | References | PDF (1.2 MB) | EPUB
  • 442 Views
  • 2 CrossRef citations
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Evaluation of two CE-IVD tests for BCR-ABL1 transcript monitoring of chronic myeloid leukemia patients
Adam Folta, Tomas Jurcek, Blanka Kubesova, Daniela Zackova, Lukas Semerad, Jiri Mayer & Ivana Jeziskova
Pages: 1239-1242
Published online: 25 Dec 2020
First Page PreviewforEvaluation of two CE-IVD tests for BCR-ABL1 transcript monitoring of chronic myeloid leukemia patients | Full Text | References | PDF (1.3 MB) | EPUB
  • 176 Views
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Ixazomib with lenalidomide and dexamethasone for patients with relapsed multiple myeloma: impact of 17p deletion and sensitivity to proteasome inhibitors from a real world data-set
Monica Ziff, Gabrielle Lawson, Dunnya De-Silva, Simon Cheesman, Charalampia Kyriakou, Shameem Mahmood, Xenofon Papanikolaou, Neil Rabin, Sajitha Sachchithananthan, Jonathan Sive, Ashutosh Wechalekar, Kwee Yong & Rakesh Popat
Pages: 1243-1246
Published online: 13 Jan 2021
First Page PreviewforIxazomib with lenalidomide and dexamethasone for patients with relapsed multiple myeloma: impact of 17p deletion and sensitivity to proteasome inhibitors from a real world data-set | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
  • 365 Views
  • 1 CrossRef citations
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Changes in nutritional status and serum proteins in children with acute lymphoblastic leukemia during induction therapy: a single-centre report from China
Jie Huang, Jian Pan, Xiaoyan Sun, Rong Wang, Xuemei Guo, Yaping Wang, Poning Liu & Yongjun Fang
Pages: 1247-1250
Published online: 28 Dec 2020
First Page PreviewforChanges in nutritional status and serum proteins in children with acute lymphoblastic leukemia during induction therapy: a single-centre report from China | Full Text | References | PDF (1.1 MB) | EPUB | Supplemental
  • 170 Views
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A case of acute myeloid leukemia with unusual germline CEBPA mutation: lessons learned about mutation detection, location, and penetrance
Hadrian Mendoza, Po-Han Chen, Alexander B. Pine, Alexa J. Siddon, Allen E. Bale, Lohith Gowda, Amy Killie, Jonica Richards, Camille Varin-Tremblay, Robert Kloss & Nikolai A. Podoltsev
Pages: 1251-1254
Published online: 19 Dec 2020
First Page PreviewforA case of acute myeloid leukemia with unusual germline CEBPA mutation: lessons learned about mutation detection, location, and penetrance | Full Text | References | PDF (881 KB) | EPUB | Supplemental
  • 334 Views
  • 4 CrossRef citations
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An analysis of the RUNX1p.(Leu56Ser) variant in a cohort of individuals with myeloid neoplasms; suggests it is a benign germline variant
David Palmer & Elisabeth Nacheva
Pages: 1255-1258
Published online: 21 Dec 2020
First Page PreviewforAn analysis of the RUNX1p.(Leu56Ser) variant in a cohort of individuals with myeloid neoplasms; suggests it is a benign germline variant | Full Text | References | PDF (684.5 KB) | EPUB
  • 95 Views
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Letter
Development of BCR-ABL1-positive ɤδ T-cell leukemia after treatment for thymoma type B1
Toshiki Terao, Hiroya Ashimine, Naoko Tsuyama, Daisuke Ikeda, Ayumi Kuzume, Rikako Tabata, Takafumi Tsushima, Daisuke Miura, Kentaro Narita, Masami Takeuchi, Kengo Takeuchi & Kosei Matsue
Pages: 1259-1262
Published online: 07 Dec 2020
First Page PreviewforDevelopment of BCR-ABL1-positive ɤδ T-cell leukemia after treatment for thymoma type B1 | Full Text | References | PDF (1.3 MB) | EPUB
  • 104 Views
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Letter
Intraperitoneal bleeding as the initial presentation of Randall-type monoclonal immunoglobulin deposition disease with hepatic involvement
Vasiliki Gkalea, Xavier Amiot, Thierry Jo Molina, Laurent Frenzel & Claude Bachmeyer
Pages: 1263-1266
Published online: 10 Dec 2020
First Page PreviewforIntraperitoneal bleeding as the initial presentation of Randall-type monoclonal immunoglobulin deposition disease with hepatic involvement | Full Text | References | PDF (1.1 MB) | EPUB
  • 75 Views
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Letter
Arsenic trioxide and all-trans retinoic acid in the treatment of children with newly diagnosed acute promyelocytic leukemia
Shuang-Yue Li, Ying Lu, Hsiao-Chuan Liu, Eun Ji Gang, Jing Le, Su-Ying Qian, Shan-Hao Tang, Ting Si & Ren-Zhi Pei
Pages: 1267-1270
Published online: 13 Jan 2021
First Page PreviewforArsenic trioxide and all-trans retinoic acid in the treatment of children with newly diagnosed acute promyelocytic leukemia | Full Text | References | PDF (711.5 KB) | EPUB
  • 209 Views
  • 1 CrossRef citations
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Letter
Hepatitis B reverse seroconversion despite entecavir prophylaxis in a myeloma patient on multiple novel agents: a case report and review of the literature
Gemma Reynolds, Tamasine Stewart, Simon J. Harrison, Andrew Spencer & Benjamin W. Teh
Pages: 1271-1274
Published online: 04 Dec 2020
First Page PreviewforHepatitis B reverse seroconversion despite entecavir prophylaxis in a myeloma patient on multiple novel agents: a case report and review of the literature | Full Text | References | PDF (474.8 KB) | EPUB
  • 190 Views
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Letter
Novel BRCA2 c.8434_8435insTT (p. Gly2812Valfs*10) mutation in a family with multiple hematologic malignancies and solid tumors
Faye Yin, Ben Kosewski & Maria R. Baer
Pages: 1275-1277
Published online: 21 Dec 2020
First Page PreviewforNovel BRCA2 c.8434_8435insTT (p. Gly2812Valfs*10) mutation in a family with multiple hematologic malignancies and solid tumors | Full Text | References | PDF (487.7 KB) | EPUB
  • 109 Views
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Flow cytometry is superior to conventional cytology in the surveillance evaluation of paucicellular cerebrospinal fluids
Yu Yang, Domos Kellermayer, Amanda Calleroz, Natalia Golardi, Christie Finch, Vijayalakshmi Padmanabhan, Marwan Yared & Reka Szigeti
Pages: 1278-1280
Published online: 21 Dec 2020
First Page PreviewforFlow cytometry is superior to conventional cytology in the surveillance evaluation of paucicellular cerebrospinal fluids | Full Text | References | PDF (411.8 KB) | EPUB
  • 87 Views
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