Pharmaceutical Development and Technology, Volume 22, Issue 7 (2017)

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Pharmaceutical Development and Technology, Volume 22, Issue 7 (2017)

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Issue Theme: Pharmaceutical QbD, statistical analysis and experimental design optimization

Research Article

Article
Development and experimental design of a novel controlled-release matrix tablet formulation for indapamide hemihydrate
Packa Antovska, Sonja Ugarkovic, Gjorgji Petruševski, Bosilka Stefanova, Blagica Manchevska, Rumenka Petkovska & Petre Makreski
Pages: 851-859
Published online: 24 Sep 2015
AbstractforDevelopment and experimental design of a novel controlled-release matrix tablet formulation for indapamide hemihydrate | Full Text | References | PDF (1.2 MB)
  • 232 Views
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Article
Nanoparticulate fingolimod delivery system based on biodegradable poly (3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV): design, optimization, characterization and in-vitro evaluation
Leila Rezaie Shirmard, Nika Bahari Javan, Mohammad Reza Khoshayand, Abbas Kebriaee-zadeh, Rassoul Dinarvand & Farid A. Dorkoosh
Pages: 860-870
Published online: 11 Nov 2015
AbstractforNanoparticulate fingolimod delivery system based on biodegradable poly (3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV): design, optimization, characterization and in-vitro evaluation | Full Text | References | PDF (2.1 MB)
  • 328 Views
  • 19 CrossRef citations
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Article
In vitro/in vivo correlation and modeling of emitted dose and lung deposition of inhaled salbutamol from metered dose inhalers with different types of spacers in noninvasively ventilated patients
Raghda R. S. Hussein, Ahmed M. A. Ali, Heba F. Salem, Maha M. Abdelrahman, Amira S. A. Said & Mohamed E. A. Abdelrahim
Pages: 871-880
Published online: 25 Nov 2015
AbstractforIn vitro/in vivo correlation and modeling of emitted dose and lung deposition of inhaled salbutamol from metered dose inhalers with different types of spacers in noninvasively ventilated patients | Full Text | References | PDF (1.2 MB)
  • 391 Views
  • 33 CrossRef citations
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Article
Quality by design approach: antioxidant activity of the tablets containing cornelian cherry fruits in relation to their composition and physical properties
Slavomír Kurhajec, Aleš Franc, Petr Doležel & Dana Sabadková
Pages: 881-888
Published online: 13 Jan 2016
AbstractforQuality by design approach: antioxidant activity of the tablets containing cornelian cherry fruits in relation to their composition and physical properties | Full Text | References | PDF (942.1 KB)
  • 220 Views
  • 4 CrossRef citations
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Article
An integrated, quality by design (QbD) approach for design, development and optimization of orally disintegrating tablet formulation of carbamazepine
Saurabh M. Mishra & Bhagwan D. Rohera
Pages: 889-903
Published online: 27 Jun 2016
AbstractforAn integrated, quality by design (QbD) approach for design, development and optimization of orally disintegrating tablet formulation of carbamazepine | Full Text | References | PDF (3.9 MB)
  • 884 Views
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Article
Determination of process variables affecting drug particle attrition within multi-component blends during powder feed transmission
John F. Gamble, Andrew B. Dennis, Paul Hutchins, John W. Jones, Pauline Musembi & Mike Tobyn
Pages: 904-909
Published online: 27 Jun 2016
AbstractforDetermination of process variables affecting drug particle attrition within multi-component blends during powder feed transmission | Full Text | References | PDF (722.5 KB)
  • 287 Views
  • 9 CrossRef citations
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Article
Experimental design-based optimization of lipid nanocarrier as delivery system against Mycobacterium species: in vitro and in vivo evaluation
Afzal Hussain, Sandeep Kumar Singh, Priya Ranjan Prasad Verma, Neeru Singh & Farhan Jalees Ahmad
Pages: 910-927
Published online: 02 Aug 2016
AbstractforExperimental design-based optimization of lipid nanocarrier as delivery system against Mycobacterium species: in vitro and in vivo evaluation | Full Text | References | PDF (4.8 MB)
  • 92 Views
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Article
Multiple response optimization of processing and formulation parameters of Eudragit RL/RS-based matrix tablets for sustained delivery of diclofenac
Ehab M. Elzayat, Ali A. Abdel-Rahman, Sayed M. Ahmed, Fars K. Alanazi, Walid A. Habib & Adel Sakr
Pages: 928-938
Published online: 28 Jul 2016
AbstractforMultiple response optimization of processing and formulation parameters of Eudragit RL/RS-based matrix tablets for sustained delivery of diclofenac | Full Text | References | PDF (2.5 MB)
  • 125 Views
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Article
Optimization of thermoreversible poloxamer gel system using QbD principle
Eunmi Ban, Dong-Jin Jang, Su-Jin Kim, Mijung Park & Aeri Kim
Pages: 939-945
Published online: 01 Sep 2016
AbstractforOptimization of thermoreversible poloxamer gel system using QbD principle | Full Text | References | PDF (1.1 MB)
  • 301 Views
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