Xenobiotica, Volume 37, Issue 2 (2007)

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Xenobiotica, Volume 37, Issue 2 (2007)

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Research Article

Article
Effect of valerian, valerian/hops extracts, and valerenic acid on glucuronidation in vitro
K. M. Alkharfy & R. F. Frye
Pages: 113-123
Published online: 22 Sep 2008
AbstractforEffect of valerian, valerian/hops extracts, and valerenic acid on glucuronidation in vitro | Full Text | References | PDF (103 KB)
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Article
Attenuating pregnane X receptor (PXR) activation: A molecular modelling approach
Y.-D. Gao, S. H. Olson, J. M. Balkovec, Y. Zhu, I. Royo, J. Yabut, R. Evers, E. Y. Tan, W. Tang, D. P. Hartley & R. T. Mosley
Pages: 124-138
Published online: 22 Sep 2008
AbstractforAttenuating pregnane X receptor (PXR) activation: A molecular modelling approach | Full Text | References | PDF (288.2 KB)
  • 801 Views
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Article
Drug–drug interactions in the metabolism of imidafenacin: Role of the human cytochrome P450 enzymes and UDP-glucuronic acid transferases, and potential of imidafenacin to inhibit human cytochrome P450 enzymes
N. Kanayama, C. Kanari, Y. Masuda, S. Ohmori & T. Ooie
Pages: 139-154
Published online: 22 Sep 2008
AbstractforDrug–drug interactions in the metabolism of imidafenacin: Role of the human cytochrome P450 enzymes and UDP-glucuronic acid transferases, and potential of imidafenacin to inhibit human cytochrome P450 enzymes | Full Text | References | PDF (104 KB)
  • 205 Views
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Article
Comparative modelling of the human UDP-glucuronosyltransferases: Insights into structure and mechanism
C. W. Locuson & T. S. Tracy
Pages: 155-168
Published online: 22 Sep 2008
AbstractforComparative modelling of the human UDP-glucuronosyltransferases: Insights into structure and mechanism | Full Text | References | PDF (756.9 KB)
  • 496 Views
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Article
Identification of human cytochrome P450 enzymes involved in the major metabolic pathway of fluvoxamine
M. Miura & T. Ohkubo
Pages: 169-179
Published online: 22 Sep 2008
AbstractforIdentification of human cytochrome P450 enzymes involved in the major metabolic pathway of fluvoxamine | Full Text | References | PDF (83.8 KB)
  • 385 Views
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Article
Induction of cytochrome P450 enzymes in rat liver by two conazoles, myclobutanil and triadimefon
G. Sun, R. D. Grindstaff, S.-F. Thai, G. R. Lambert, D. B. Tully, D. J. Dix & S. Nesnow
Pages: 180-193
Published online: 22 Sep 2008
AbstractforInduction of cytochrome P450 enzymes in rat liver by two conazoles, myclobutanil and triadimefon | Full Text | References | PDF (116.3 KB)
  • 193 Views
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Article
Metabolism of (−)-fenchone by CYP2A6 and CYP2B6 in human liver microsomes
M. Miyazawa & K. Gyoubu
Pages: 194-204
Published online: 22 Sep 2008
AbstractforMetabolism of (−)-fenchone by CYP2A6 and CYP2B6 in human liver microsomes | Full Text | References | PDF (155.8 KB)
  • 151 Views
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Article
Characterization of benzimidazole and other oxidative and conjugative metabolites of brimonidine in vitro and in rats in vivo using on-line H/D exchange LC-MS/MS and stable-isotope tracer techniques
J. Ni, J. Rowe, T. Heidelbaugh, S. Sinha & A. Acheampong
Pages: 205-220
Published online: 22 Sep 2008
AbstractforCharacterization of benzimidazole and other oxidative and conjugative metabolites of brimonidine in vitro and in rats in vivo using on-line H/D exchange LC-MS/MS and stable-isotope tracer techniques | Full Text | References | PDF (211.7 KB)
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